Exposure of Lung Epithelial Cells to Photochemically Aged Secondary Organic Aerosol Shows Increased Toxic Effects DOI
Pratiti Home Chowdhury, Quanfu He,

Tatyana Lasitza Male

et al.

Environmental Science & Technology Letters, Journal Year: 2018, Volume and Issue: 5(7), P. 424 - 430

Published: June 11, 2018

Adverse health effects due to exposure particulate matter (PM) are among the most important global environmental risks. However, of secondary organic aerosols (SOA), a major component aerosol, largely unknown. Here we exposed lung epithelial cells (A549) fresh and aged SOA particles investigated effect atmospheric aging on cell viability gene expression. Naphthalene- α-pinene-derived were formed in an oxidation flow reactor that simulates formation dominated by OH radical under NOx-free conditions. The mass chemical composition characterized on-line using scanning mobility particle sizer aerosol spectrometer. Fresh directed air–liquid interface system. Aged naphthalene- somewhat more toxic than SOA. naphthalene contained peroxide levels higher those level induction Nrf2 signaling increased following Given prevalence its observed toxicity, this study calls for studies aimed at understanding underlying mechanics.

Language: Английский

Air Pollution and Cardiovascular Disease DOI Creative Commons
Sanjay Rajagopalan, Sadeer Al‐Kindi, Robert D. Brook

et al.

Journal of the American College of Cardiology, Journal Year: 2018, Volume and Issue: 72(17), P. 2054 - 2070

Published: Oct. 1, 2018

Language: Английский

Citations

993

Emission of trace gases and aerosols from biomass burning – an updated assessment DOI Creative Commons
Meinrat O. Andreae

Atmospheric chemistry and physics, Journal Year: 2019, Volume and Issue: 19(13), P. 8523 - 8546

Published: July 4, 2019

Abstract. Since the publication of compilation biomass burning emission factors by Andreae and Merlet (2001), a large number studies have greatly expanded amount available data on emissions from various types burning. Using essentially same methodology as this paper presents an updated factors. The over 370 published were critically evaluated integrated into consistent format. Several new categories added, species for which are presented was increased 93 to 121. Where field still insufficient, estimates based appropriate extrapolation techniques proposed. For key species, compared with previously values. Based these global activity estimates, I derived pyrogenic important released

Language: Английский

Citations

854

Sources of particulate-matter air pollution and its oxidative potential in Europe DOI

Kaspar R. Daellenbach,

Gaëlle Uzu, Jianhui Jiang

et al.

Nature, Journal Year: 2020, Volume and Issue: 587(7834), P. 414 - 419

Published: Nov. 18, 2020

Language: Английский

Citations

646

Indoor Air Pollution, Related Human Diseases, and Recent Trends in the Control and Improvement of Indoor Air Quality DOI Open Access
Vinh Van Tran, Duckshin Park, Young‐Chul Lee

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2020, Volume and Issue: 17(8), P. 2927 - 2927

Published: April 23, 2020

Indoor air pollution (IAP) is a serious threat to human health, causing millions of deaths each year. A plethora pollutants can result in IAP; therefore, it very important identify their main sources and concentrations devise strategies for the control enhancement indoor quality (IAQ). Herein, we provide critical review evaluation major pollutant emissions, health effects, issues related IAP-based illnesses, including sick building syndrome (SBS) building-related illness (BRI). In addition, approaches reduction are pointed out, recent trends efforts resolve improve IAQ, with respective advantages potentials, summarized. It predicted that development novel materials sensors, IAQ-monitoring systems, smart homes promising strategy IAQ future.

Language: Английский

Citations

564

Recent Insights into Particulate Matter (PM2.5)-Mediated Toxicity in Humans: An Overview DOI Open Access
Prakash Thangavel, Duckshin Park, Young‐Chul Lee

et al.

International Journal of Environmental Research and Public Health, Journal Year: 2022, Volume and Issue: 19(12), P. 7511 - 7511

Published: June 19, 2022

Several epidemiologic and toxicological studies have commonly viewed ambient fine particulate matter (PM2.5), defined as particles having an aerodynamic diameter of less than 2.5 µm, a significant potential danger to human health. PM2.5 is mostly absorbed through the respiratory system, where it can infiltrate lung alveoli reach bloodstream. In reactive oxygen or nitrogen species (ROS, RNS) oxidative stress stimulate generation mediators pulmonary inflammation begin promote numerous illnesses. According most recent data, matter, PM2.5, responsible for nearly 4 million deaths globally from cardiopulmonary illnesses such heart disease, infections, chronic cancers, preterm births, other There has been increased worry in years about negative impacts this worldwide danger. The causal associations between health, toxic effects mechanisms molecular pathways described review.

Language: Английский

Citations

446

Real-time sensing of bioaerosols: Review and current perspectives DOI Creative Commons
J. A. Huffman, A. E. Perring, Nicole Savage

et al.

Aerosol Science and Technology, Journal Year: 2019, Volume and Issue: 54(5), P. 465 - 495

Published: Sept. 12, 2019

Detection of bioaerosols, or primary biological aerosol particles (PBAPs), has become increasingly important for a wide variety research communities and scientific questions. In particular, real-time (RT) techniques autonomous, online detection characterization PBAP properties in both outdoor indoor environments are becoming more commonplace have opened avenues research. With advances technology, however, come challenges to standardize practices so that results reliable comparable across technologies users. Here, we present critical review major RT instrument classes been applied research, especially with respect environmental science, allergy monitoring, agriculture, public health, national security. Eight covered, including the following: (i) fluorescence spectroscopy, (ii) elastic scattering, microscopy, holography, (iii) Raman (iv) mass spectrometry, (v) breakdown (vi) remote sensing, (vii) microfluidic techniques, (viii) paired aqueous techniques. For each class technology technical limitations, misconceptions, pitfalls, also summarize best operation, analysis, reporting. The final section article presents pressing questions grand sensing as well recommendations future work encourage high-quality increased cross-community collaboration.

Language: Английский

Citations

248

Anthropogenic enhancements to production of highly oxygenated molecules from autoxidation DOI Open Access
Havala O. T. Pye, Emma L. D’Ambro, Ben H. Lee

et al.

Proceedings of the National Academy of Sciences, Journal Year: 2019, Volume and Issue: 116(14), P. 6641 - 6646

Published: March 18, 2019

Atmospheric oxidation of natural and anthropogenic volatile organic compounds (VOCs) leads to secondary aerosol (SOA), which constitutes a major often dominant component atmospheric fine particulate matter (PM2.5). Recent work demonstrates that rapid autoxidation peroxy radicals (RO2) formed during VOC results in highly oxygenated molecules (HOM) efficiently form SOA. As NOx emissions decrease, the chemical regime atmosphere changes one RO2 becomes increasingly important, potentially increasing PM2.5, while oxidant availability driving formation rates simultaneously declines, possibly slowing regional PM2.5 formation. Using suite situ aircraft observations laboratory studies HOM, together with detailed molecular mechanism, we show although an archetypal biogenic system more competitive as decreases, absolute HOM production decrease due reductions, leading overall positive coupling between localized SOA from autoxidation. This effect is observed Atlanta, Georgia, urban plume where enhanced presence elevated NO, predictions for Guangzhou, China, HOM-RO2 coincides increases NO 1990 2010. These suggest added benefits abatement strategies come emission reductions have implications aerosol-climate interactions global resulting since preindustrial era.

Language: Английский

Citations

184

Possible environmental effects on the spread of COVID-19 in China DOI Open Access

Hao Xu,

Chonghuai Yan, Qingyan Fu

et al.

The Science of The Total Environment, Journal Year: 2020, Volume and Issue: 731, P. 139211 - 139211

Published: May 7, 2020

Language: Английский

Citations

178

Impacts of atmospheric particulate matter pollution on environmental biogeochemistry of trace metals in soil-plant system: A review DOI
Xiao‐San Luo, Haijian Bing, Zhuanxi Luo

et al.

Environmental Pollution, Journal Year: 2019, Volume and Issue: 255, P. 113138 - 113138

Published: Sept. 12, 2019

Language: Английский

Citations

174

Secondary organic aerosol association with cardiorespiratory disease mortality in the United States DOI Creative Commons
Havala O. T. Pye, Cavin Ward‐Caviness, Benjamin N. Murphy

et al.

Nature Communications, Journal Year: 2021, Volume and Issue: 12(1)

Published: Dec. 16, 2021

Abstract Fine particle pollution, PM 2.5 , is associated with increased risk of death from cardiorespiratory diseases. A multidecadal shift in the United States (U.S.) composition towards organic aerosol as well advances predictive algorithms for secondary (SOA) allows novel examinations role components on mortality. Here we show SOA strongly county-level rates U.S. independent total mass association largest associations located southeastern Compared to variability across 3.5× greater per capita On a basis, 6.5× higher rate mortality than and biogenic anthropogenic carbon sources both play overall Our results suggest reducing health impacts requires consideration SOA.

Language: Английский

Citations

170