Breaking the pH Limitation of Nanozymes: Mechanisms, Methods, and Applications

Advanced Materials, Journal Year: 2024, Volume and Issue: 36(31)

Published: April 14, 2024

Although nanozymes have drawn great attention over the past decade, activities of peroxidase-like, oxidase-like, and catalase-like are often pH dependent with elusive mechanism, which largely restricts their application. Therefore, a systematical discussion on pH-related catalytic mechanisms together methods to overcome this limitation is in need. In review, various exhibiting pH-dependent collected root causes for dependence comprehensively analyzed. Subsequently, regulatory concepts including environment reconstruction direct activity improvement break restriction summarized. Moreover, applications pH-independent sensing, disease therapy, pollutant degradation overviewed. Finally, current challenges future opportunities development suggested. It anticipated that review will promote further design broaden application range higher efficiency.

Language: Английский

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Enhancing the peroxidase-like activity of MoS2-based nanozymes by introducing attapulgite for antibacterial application and sensitive detection of glutathione

Nano Research, Journal Year: 2024, Volume and Issue: 17(8), P. 7415 - 7426

Published: May 17, 2024

Language: Английский

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Biological Ce/Fe-Metal Organic Framework Multifunctional Nanozyme-Based Colorimetric Sensor Array for Multi-Analyte Detection in Human Sweat

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 423, P. 136769 - 136769

Published: Oct. 11, 2024

Language: Английский

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Strategies for Improving Performance of Iron-Based Catalysts in Activating Heterogeneous Fenton-Like Oxidation in Pollutants Degradation: From the Perspective Of Materials Structure Design

Process Safety and Environmental Protection, Journal Year: 2024, Volume and Issue: 190, P. 794 - 820

Published: Aug. 27, 2024

Language: Английский

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Regulatory Mechanisms of Cytotoxicity and Hemocompatibility Induced by Phase Transformation of Kaolinite Nanocarrier

The Journal of Physical Chemistry Letters, Journal Year: 2025, Volume and Issue: unknown, P. 3945 - 3953

Published: April 10, 2025

Revealing the regulatory mechanism underlying cytotoxicity and hemocompatibility of nanocarriers is crucial for their biofunctionalized design practical application in nanotherapeutics. However, microstructural physicochemical properties inevitably change during modification process, impact these changes on biosafety remains unclear. Herein, we investigate effects phase transformation kaolinite (Kaol) nanoclay its biosafety. Experimental results indicate that adjoint dehydration, dehydroxylation, disaggregation Kaol could alter mode interaction at cell interface mitigate damage to membranes. Furthermore, heat-treated exhibits reduced hemolysis while maintaining red blood adhesion pro-coagulant functions, without affecting structure plasma proteins. Collectively, this study provide a novel insight into correlation between microstructure

Language: Английский

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Cerium-based metal–organic framework nanozyme with high oxidase-like activity at neutral pH for discrimination and detection of antioxidants

Biosensors and Bioelectronics, Journal Year: 2025, Volume and Issue: unknown, P. 117608 - 117608

Published: May 1, 2025

Language: Английский

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The mechanism of intrinsic peroxidase (POD)-like activity of attapulgite

Analytical and Bioanalytical Chemistry, Journal Year: 2024, Volume and Issue: 416(27), P. 6033 - 6044

Published: April 11, 2024

Language: Английский

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