A Review on Molecular Iodine Catalyzed/Mediated Multicomponent Reactions

Asian Journal of Organic Chemistry, Journal Year: 2022, Volume and Issue: 12(1)

Published: Nov. 26, 2022

Abstract In multicomponent reactions, three or more reactants combine in one pot to form a product without the isolation of intermediate and most contribute newly formed reducing number steps involved waste generated. Molecular iodine is mild, efficient, relatively nontoxic, inexpensive, commercially available, catalyzes various organic reactions due its Lewis acidic behaviour. The development catalyzed by molecular indeed good green alternative for synthetic chemistry. aim this article review all important reported since 2013 order envisage some new efficient protocols synthesis structurally complex molecules.

Language: Английский

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Oxidative dual C–H sulfenylation: A strategy for the synthesis of bis(imidazo[1,2-a]pyridin-3-yl)sulfanes under metal-free conditions using sulfur powder

Chinese Chemical Letters, Journal Year: 2020, Volume and Issue: 32(5), P. 1705 - 1708

Published: Dec. 28, 2020

Language: Английский

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Supramolecular aggregation patterns featuring Se⋯N secondary-bonding interactions in mono-nuclear selenium compounds: A comparison with their congeners

Coordination Chemistry Reviews, Journal Year: 2021, Volume and Issue: 443, P. 214031 - 214031

Published: May 26, 2021

Language: Английский

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Copper-Catalyzed C-3 Functionalization of Imidazo[1,2-a]pyridines with 3-Indoleacetic Acids

The Journal of Organic Chemistry, Journal Year: 2021, Volume and Issue: 86(17), P. 12394 - 12402

Published: Aug. 13, 2021

A copper-catalyzed C-3 functionalization of imidazo[1,2-a]pyridines with 3-indoleacetic acids through an aerobic oxidative decarboxylative process has been developed. The protocol provided a series 3-(1H-indol-3-ylmethyl)-imidazo[1,2-a]pyridines in moderate to good yields under simple reaction conditions. Importantly, some products exhibited potent antiproliferative activity cancer cell lines.

Language: Английский

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Visible-Light-Promoted Selenocyanation of Cyclobutanone Oxime Esters Using Potassium Selenocyanate

The Journal of Organic Chemistry, Journal Year: 2021, Volume and Issue: 86(17), P. 11399 - 11406

Published: Aug. 9, 2021

We report the visible-light-promoted selenocyanation of cyclobutanone oxime esters using potassium selenocyanate in presence a fac-Ir(ppy)3 catalyst for first time. Because mild conditions employed and use readily accessible selenocyanate, this method is an effective green strategy synthesis cyano selenocyano bifunctional substituted alkanes.

Language: Английский

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Ruthenium-Catalyzed C(sp²)–H Bond Bisallylation with Imidazopyridines as Directing Groups

The Journal of Organic Chemistry, Journal Year: 2020, Volume and Issue: 85(23), P. 15167 - 15182

Published: Nov. 3, 2020

A Ru(II)-catalyzed bisallylation of imidazopyridines with vinylcyclopropanes or vinyl cyclic carbonate has been successfully realized. Notably, pharmacophore imidazopyridine was utilized as an intrinsic directing group, which gave access to value-added bisallylated products in high yields via double tandem C-H and C-C/C-O activation. The current methodology featured broad substrate scope, good functional group compatibility, operational simplicity.

Language: Английский

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Iodine pentoxide-mediated oxidative selenation and seleno/thiocyanation of electron-rich arenes

Organic & Biomolecular Chemistry, Journal Year: 2022, Volume and Issue: 20(27), P. 5463 - 5469

Published: Jan. 1, 2022

A simple and efficient method for the regioselective selenation of electron-rich arenes by employing non-metal inorganic iodine pentoxide (I2O5) as a reaction promoter under ambient conditions has been developed. The present protocol showed broad functional group tolerance easy-to-operate time-economical features. Additionally, this also allows access to 3-seleno 3-thiocyanoindoles use readily available selenocyanate thiocyanate salts. mechanistic study indicated that transformation operated through selenenyl iodide-induced electrophilic substitution processes.

Language: Английский

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Electrochemical-induced regioselective C-3 thiocyanation of imidazoheterocycles with hydrogen evolution

Tetrahedron Letters, Journal Year: 2021, Volume and Issue: 65, P. 152755 - 152755

Published: Jan. 7, 2021

Language: Английский

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C(sp²)‐H Imination of Imidazo[1,2‐a]pyridines: A Catalyst‐Free, Multicomponent Approach

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(19)

Published: March 5, 2024

Abstract We report here a catalyst‐free, (sp 2 )C−H imination reaction of in‐situ formed imidazo[1,2‐ ]pyridines and α‐iminoketones. This one‐pot, multicomponent, atom economic is performed at moderate to room temperature without the need for any catalyst inert conditions. The showed good substrate tolerance with appreciable yields. Gram‐scale synthesis post‐synthetic modifications obtain 1,2‐diketones are also described.

Language: Английский

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Copper complex supported on the surface of magnetic nanoparticles: an ecofriendly catalyst for C–S and C–Se coupling reactions

Journal of the Iranian Chemical Society, Journal Year: 2024, Volume and Issue: 21(6), P. 1547 - 1560

Published: April 27, 2024

Language: Английский

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