ACS Omega,
Journal Year:
2024,
Volume and Issue:
9(8), P. 9256 - 9268
Published: Feb. 13, 2024
Biopolymer
blends
have
attracted
considerable
attention
in
industrial
applications
due
to
their
notable
mechanical
properties
and
biodegradability.
This
work
delves
into
the
innovative
combination
of
butadiene-acrylonitrile
(referred
as
NBR)
with
a
pectin-based
biopolymer
(NGP)
at
90:10
mass
ratio
through
detailed
analysis
employing
characterization,
Fourier
transform
infrared
(FTIR)
analysis,
thermogravimetric
(TGA),
morphology
studies
using
SEM.
Additionally,
biopolymer's
biodegradability
under
aerobic
anaerobic
conditions
is
tested.
The
study's
findings
underscore
superior
tensile
strength
elongation
break
NGP/NBR
blend
comparison
pure
NBR,
while
also
exhibiting
decrease
puncture
resistance
imperfect
bonds
particle–matrix
interfaces,
necessitating
use
compatibilizer.
In
conditions,
evaluation
biodegradable
reveals
2%
12%
NBR
blend,
respectively.
degradation
were
aligned
TGA
results
highlighting
lower
decomposition
temperature
for
NGP.
this
research
integrates
application
conditional
value-at-risk
(CVaR)-based
blend's
evaluate
uncertainty
impact
experiment.
Under
risk,
significant
enhancement
performance
(by
80%)
was
shown
compared
NBR.
Ultimately,
study
shows
that
adding
pectin
compound
amplifies
overall
significantly
select
criteria.
Chemistry & Biodiversity,
Journal Year:
2024,
Volume and Issue:
21(8)
Published: May 23, 2024
Thirteen
novel
hydrazone-Schiff
bases
(3-15)
of
fexofenadine
were
succesfully
synthesized,
structurally
deduced
and
finally
assessed
their
capability
to
inhibit
urease
enzyme
(in
vitro).
In
the
series,
six
compounds
12
(IC
Synthetic Communications,
Journal Year:
2024,
Volume and Issue:
54(9), P. 709 - 734
Published: March 28, 2024
Research
on
benzimidazole
derivatives
is
always
an
attractive
challenge
among
synthetic
chemists
because
are
very
key
and
important
components
in
the
structure
of
many
drugs,
biological
active
molecules,
natural
products.
Benzimidazole
interesting
their
valuable
medicinal
activities,
such
as
anti-bacterial,
anti-cancer,
anti-tuberculosis,
anti-fungal,
pain
killer,
anti-HIV
activities.
During
last
decade,
most
reports
field
catalysts
have
been
related
to
magnetic
nanocatalysts,
which
shows
high
popularity
remarkable
efficiency
this
type
catalyst
performing
chemical
reactions.
Magnetic
nanocatalysts
ideal
both
from
point
view
green
chemistry
economically
they
easily
separated
reaction
mixture
significant
catalytic
activity.
In
review
article,
we
summarized
methods
presented
synthesis
various
based
use
nanomaterials
recoverable
catalysts.
Scientific Reports,
Journal Year:
2024,
Volume and Issue:
14(1)
Published: May 18, 2024
Abstract
A
series
of
novel
Schiff
base
derivatives
(1–28)
3,4-dihydroxyphenylacetic
acid
were
synthesized
in
a
multi-step
reaction.
All
the
bases
obtained
high
yields
and
their
structures
determined
by
1
HNMR,
13
CNMR,
HR-ESI–MS
spectroscopy.
Except
for
compounds
22
,
26
27,
28,
all
show
excellent
to
moderate
α-glucosidase
inhibition.
Compounds
5
(IC
50
=
12.84
±
0.52
µM),
4
13.64
0.58
12
15.73
0.71
16.62
0.47
15
17.40
0.74
3
18.45
1.21
7
19.68
0.82
2
20.35
1.27
µM)
shows
outstanding
inhibition
as
compared
standard
acarbose
873.34
1.67
µM).
Furthermore,
docking
study
was
performed
find
out
interaction
between
enzyme
most
active
compounds.
With
this
research
work,
have
been
introduced
potential
class
inhibitors
that
remained
elusive
till
now.
Pharmaceuticals,
Journal Year:
2023,
Volume and Issue:
16(12), P. 1677 - 1677
Published: Dec. 1, 2023
Diabetes
mellitus
(DM)
is
a
non-communicable,
life-threatening
syndrome
that
present
all
over
the
world.
The
use
of
eco-friendly,
cost-effective,
and
green-synthesised
nanoparticles
as
medicinal
therapy
in
treatment
DM
an
attractive
option.In
study,
silver
(AI-AgNPs)
were
biosynthesized
through
green
synthesis
method
using
Azadirachta
indica
seed
extract
to
evaluate
their
anti-diabetic
potentials.These
characterized
by
UV-visible
spectroscopy,
Fourier
transform
infrared
spectrophotometers
(FTIR),
scanning
electron
microscopy
(SEM),
DLS,
X-ray
diffraction
(XRD).
AI-AgNPs
crude
extracts
seeds
evaluated
for
potentials
glucose
adsorption
assays,
uptake
yeast
cells
alpha-amylase
inhibitory
assays.Al-AgNPs
showed
highest
activity
(75
±
1.528%),
while
(63
2.5%)
at
80
µg/mL.
In
assay,
Al-AgNPs
was
10.65
1.58%,
8.32
0.258%
30
mM,
whereas
exhibited
maximum
73.85
1.114%
65.85
2.101%
100
assay
results
substantial
dose-dependent
activities.
Further,
also
investigated
streptozotocin-induced
diabetic
mice.
Mice
administered
with
(10
40
mg/kg
b.w)
days.The
considerable
drop
blood
sugar
levels,
including
pancreatic
liver
cell
regeneration,
demonstrating
have
strong
potential.
RSC Advances,
Journal Year:
2024,
Volume and Issue:
14(2), P. 812 - 830
Published: Jan. 1, 2024
Growing
demand
for
eco-friendly
catalysts
in
drug
synthesis.
Fe
3
O
4
@AMBA-CuI
nanomaterials,
a
reusable
catalyst,
enable
synthesis
of
diaryl
and
di-heteroaryl
sulfides
from
diverse
substrates.
Reusability
tests
confirm
stability,
maintaining
magnetic
properties
through
six
uses,
yielding
sulfides.
