Visible light-driven and substrate-promoted alkenyltrifluoromethylation of alkenes to synthesize CF3-functionalized 1,4-naphthoquinones DOI
Lin Tang,

Fengjuan Jia,

Ruijun Yu

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

The first example of the visible light-driven and substrate-promoted three-component alkenyltrifluoromethylation alkenes is developed. This approach uses easily available alkenes, 2-arylamino-1,4-naphthoquinones Togni reagent as reactants, describes good functionality tolerance. reaction offers a precise synthesis valuable CF

Language: Английский

Direct Functionalization of para‐Quinones: A Historical Review and New Perspectives DOI
Raushan Kumar Jha, Sangit Kumar

European Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 27(27)

Published: May 21, 2024

Abstract The direct functionalization of quinones has always fascinated research communities due to their biological and redox activities subsequent application. Quinone motifs play a vital role as precursors for many bioactive compounds materials; hence, ingenious methodologies have been elaborated exploring these units. A significant part the synthetic strategies towards functionalized achieved by installing substituents on hydroquinones, phenols, or quinone itself different oxidative coupling reactions via radical pathways with without utilization metal catalysts. simple C−H bond remains challenging inherited electronic nature high dissociation energy. This review article summarizes recent advancement made through quinones. Our primary focus will be approaches mechanistic that appeared in last two decades, along short historical importance family.

Language: Английский

Citations

10
Oxidative Aminotrifluoromethylation of 1,4-Naphthoquinone DOI
Lin Tang,

Fengjuan Jia,

Ruijun Yu

et al.

The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(18), P. 13117 - 13127

Published: Sept. 3, 2024

A strategy for convenient and precise oxidative aminotrifluoromethylation of 1,4-naphthoquinone with the Togni reagent amines has been demonstrated via a radical process. This method allows efficient access preparation wide range CF

Language: Английский

Citations

2
Visible-light-induced copper-catalyzed regiodivergent C(sp3)-sulfonylation of oxime esters with sodium sulfinates DOI
Ben Ma, Zhiyong Chen, Min Ma

et al.

Organic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(20), P. 5876 - 5883

Published: Jan. 1, 2024

A visible-light-induced copper-catalyzed regiodivergent sulfonylation of oxime esters with sodium sulfinates under mild conditions is reported, yielding a range useful β-ketosulfones and sulfonated pyrrolines convertible functional groups.

Language: Английский

Citations

1
Recent Progress in Metal‐Free Hydroacylation Reactions of Alkenes and Alkynes DOI
Deepa Uppal,

Abhilekha Sharma,

Surendra Singh

et al.

ChemistrySelect, Journal Year: 2024, Volume and Issue: 9(35)

Published: Sept. 12, 2024

Abstract The present review discusses the development of new metal‐free conditions for hydroacylation alkenes and alkynes under both thermal photochemical from 2018, their application to synthesis various bioactive molecules over past few years. key point highlights remarkable progress made by catalytic systems in comparison conventional metal catalysts alkenes, alkynes, arenes. Both inter‐ intramolecular reactions mechanistic pathways were discussed. most current developments several natural, pharmaceutical, heterocyclic compounds using have also been introduced.

Language: Английский

Citations

1
Visible light-driven and substrate-promoted alkenyltrifluoromethylation of alkenes to synthesize CF3-functionalized 1,4-naphthoquinones DOI
Lin Tang,

Fengjuan Jia,

Ruijun Yu

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: unknown

Published: Jan. 1, 2024

The first example of the visible light-driven and substrate-promoted three-component alkenyltrifluoromethylation alkenes is developed. This approach uses easily available alkenes, 2-arylamino-1,4-naphthoquinones Togni reagent as reactants, describes good functionality tolerance. reaction offers a precise synthesis valuable CF

Language: Английский

Citations

0