Time-encoded electrical detection of trace RNA biomarker by integrating programmable molecular amplifier on chip DOI Creative Commons
Gurpreet Kaur,

Marcel Tintelott,

Mohit Suranglikar

et al.

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 257, P. 116311 - 116311

Published: April 24, 2024

ou non, émanant des établissements d'enseignement et de recherche français étrangers, laboratoires publics privés.

Nanowire-based sensor electronics for chemical and biological applications DOI
Guozhu Zhang,

Hao Zeng,

Jiangyang Liu

et al.

The Analyst, Journal Year: 2021, Volume and Issue: 146(22), P. 6684 - 6725

Published: Jan. 1, 2021

Detection and recognition of chemical biological species via sensor electronics are important not only for various sensing applications but also fundamental scientific understanding. In the past two decades, devices using one-dimensional (1D) nanowires have emerged as promising powerful platforms electrical detection biologically relevant molecules due to their superior performance, long-term stability, ultra-low power consumption. This paper presents a comprehensive overview recent progress achievements in 1D nanowire synthesis, working principles nanowire-based sensors, analytes recognition. addition, some critical issues that hinder practical electronics, including device reproducibility selectivity, consumption, will be highlighted. Finally, challenges, perspectives, opportunities developing advanced innovative featured.

Language: Английский

Citations

31

Recent advances in field effect transistor biosensor technology for cancer detection: a mini review DOI Creative Commons
Lemeng Chao, Ying Liang, Xiao Hu

et al.

Journal of Physics D Applied Physics, Journal Year: 2021, Volume and Issue: 55(15), P. 153001 - 153001

Published: Dec. 7, 2021

Abstract Cancer is an incurable disease, and the treatment process extremely painful. Early detection may ease prevent cancer from spreading beyond primary disease area. However, conventional screening tests have long times lack required sensitivity for early detection. Consequently, traditional biosensors, including amplification refractory mutation system, digital polymerase chain reaction, next generation sequencing, western blot, electrochemical, mechanical been studied in recent years. Specifically, field effect transistor (FET) are attractive pocketable devices with short time capabilities. Because FET biosensors outstanding electrical properties, their efficacy of cancer. Traditional methods biomarkers include use biomarkers, especially gene, antigen, protein characteristics. This review presents latest strategies applications biosensing compares advantages disadvantages regarding sensing principle, configuration, performance. Especially, which antibodies, nucleic acids, proteins highlighted. Mechanical properties on performance discussed. provides a guiding role design development FET-based biosensors.

Language: Английский

Citations

30

Fast and direct identification of SARS‐CoV‐2 variants via 2D InSe field‐effect transistors DOI Creative Commons
Duo Xu, Junji Li,

Yunhai Xiong

et al.

InfoMat, Journal Year: 2023, Volume and Issue: 5(2)

Published: Jan. 2, 2023

Abstract As the COVID‐19 pandemic evolves and new variants emerge, development of more efficient identification approaches is urgent to prevent continuous outbreaks SARS‐CoV‐2. Field‐effect transistors (FETs) with two‐dimensional (2D) materials are viable platforms for detection virus nucleic acids (NAs) but cannot yet provide accurate information on NA variations. Herein, 2D Indium selenide (InSe) FETs were used identify SARS‐CoV‐2 variants. The device's mobility stability ensured by atomic layer deposition (ALD) Al 2 O 3 . resulting exhibited sub‐fM limits ranging from 10 –14 M – 8 M. recognition single‐nucleotide variations was achieved within 15 min enable fast direct two core mutations (L452R, R203M) in Delta genomes ( p < 0.01). Such capability originated trap states oxidized InSe (InSe 1− x ) after ALD, traps‐involved carrier transport responsive negative charges NAs. In sum, proposed approach might highly epidemiological timely surveillance COVID pandemic. image

Language: Английский

Citations

13

Spiers Memorial Lecture: Challenges and prospects in organic photonics and electronics DOI Creative Commons
Michele Catacchio, Mariapia Caputo, Lucia Sarcina

et al.

Faraday Discussions, Journal Year: 2024, Volume and Issue: 250, P. 9 - 42

Published: Jan. 1, 2024

While a substantial amount of research activity has been conducted in fields related to organic photonics and electronics, including the development devices such as field-effect transistors, photovoltaics, light-emitting diodes for applications encompassing thermoelectrics, batteries, excitonic materials photochemical optoelectronic applications, this perspective review will primarily concentrate on emerging rapidly expanding domain bioelectronics neuromorphics. Here we present most recent findings transistors capable sensing biological biomarkers down at single-molecule level (

Language: Английский

Citations

4

Time-encoded electrical detection of trace RNA biomarker by integrating programmable molecular amplifier on chip DOI Creative Commons
Gurpreet Kaur,

Marcel Tintelott,

Mohit Suranglikar

et al.

Biosensors and Bioelectronics, Journal Year: 2024, Volume and Issue: 257, P. 116311 - 116311

Published: April 24, 2024

ou non, émanant des établissements d'enseignement et de recherche français étrangers, laboratoires publics privés.

Citations

4