Chem Catalysis, Journal Year: 2024, Volume and Issue: unknown, P. 101159 - 101159
Published: Nov. 1, 2024
Language: Английский
Chem Catalysis, Journal Year: 2024, Volume and Issue: unknown, P. 101159 - 101159
Published: Nov. 1, 2024
Language: Английский
Green Synthesis and Catalysis, Journal Year: 2025, Volume and Issue: unknown
Published: May 1, 2025
Language: Английский
Citations
0The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(18), P. 13085 - 13092
Published: Aug. 28, 2024
An amidoarylcarbonylation reaction of aromatic aldehydes and olefins with Katritzky pyridinium salts by N-heterocyclic carbene (NHC)-catalyzed radical relay to construct C-C C-N bonds good functional group tolerance is developed for the synthesis β-acylamino ketones. This gentle efficient approach offers a valuable style Mechanistic studies revealed that addition/coupling/elimination cascade process was involved in this reaction.
Language: Английский
Citations
2Chinese Journal of Chemistry, Journal Year: 2024, Volume and Issue: unknown
Published: Sept. 10, 2024
Comprehensive Summary A visible‐light‐induced decarboxylative radical cascade cyclization reaction between N ‐(2‐cyanoaryl)‐acrylamides and alkyl ‐(acyloxy)phthalimide (NHPI esters) for the construction of phenanthridine derivatives has been developed. This approach utilizes lithium iodide (LiI) triphenylphosphine (PPh 3 ) as redox catalysts is produced through photoactivation electron donor‐acceptor (EDA) complex. series primary, secondary, tertiary alkyl‐substituted phenanthridines are prepared in up to 82% yield without transition‐metal catalysts, chemical oxidants, or metal‐/organic dye‐based photocatalysts.
Language: Английский
Citations
2Organic Letters, Journal Year: 2024, Volume and Issue: 26(42), P. 9068 - 9072
Published: Oct. 11, 2024
A variety of polycyclic benzazepines were rapidly constructed by NHC-catalyzed regioselective redox-neutral intramolecular tandem cyclization. Initial mechanistic studies revealed that a SET radical process was possibly involved.
Language: Английский
Citations
2The Journal of Organic Chemistry, Journal Year: 2023, Volume and Issue: 88(23), P. 16556 - 16565
Published: Nov. 16, 2023
Herein, an N-heterocyclic carbene (NHC)-catalyzed tandem cyclization/addition/cyclization reaction of 2-isocyanobiaryls and α-bromo-N-cinnamylamides for the synthesis 2-pyrrolidinone-functionalized phenanthridines is developed. This protocol features a radical cascade process, broad substrate scope, good functional group compatibility under metal- oxidant-free conditions.
Language: Английский
Citations
5Chemistry - A European Journal, Journal Year: 2022, Volume and Issue: 29(12)
Published: Nov. 29, 2022
Despite a recent proposal on the mechanism of single-electron transfer (SET) process between tritylium and 2,6-bis(diisopropylphenyl)imidazol-2-ylidene (IPr) based evidence transient IPr radical cation intermediate ([IPr]⋅+ ) formation, such oxidation is still contentious because high potential N-heterocyclic carbenes. Our experimental analysis indicates that appearance deep purple color, previously considered to be from [IPr]⋅+ , originates zwitterionic (3 a), not cation. Here, we propose an alternative for reaction involving IPr. This noteworthy explaining how [NHC-H]+ can generated without formation [NHC]⋅+ which has been frequently proposed as NHC oxidants. These results also show strong donor a) could by oxidants using NHCs, more feasible explanation reactivity NHCs with
Language: Английский
Citations
7Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(17), P. 3624 - 3630
Published: June 21, 2024
Abstract A tandem oxidative radical functionalization/annulation of N ‐acryloyl amino saccharin is disclosed. This strategy allows the facile construction diversely functionalized 3,4‐fused tricyclic benzosultams that previously have not been reported. wide range functionalities were installed through formation C−C, C−S and C−P bond enabled by respective radicals.
Language: Английский
Citations
1The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(17), P. 12753 - 12761
Published: Aug. 27, 2024
We disclose a rapid and nontoxic procedure to construct various oxindoles. This method harnesses the power of catalytic amount quinone in synergy with Cs2CO3, showcasing remarkable compatibility wide range functional groups. Mechanistic investigations reveal that it operates via radical pathway, likely initiated by single-electron transfer from quinone-Cs2CO3 complexes. pivotal electron event leads generation crucial alkyl intermediate, contributing overall success efficacy transformation.
Language: Английский
Citations
1Organic Letters, Journal Year: 2024, Volume and Issue: 26(36), P. 7744 - 7750
Published: Sept. 5, 2024
A chemoselective and regioselective copper-promoted defunctionalization procedure has been developed, enabling the rapid construction of various
Language: Английский
Citations
1The Journal of Organic Chemistry, Journal Year: 2024, Volume and Issue: 89(18), P. 13128 - 13136
Published: Sept. 11, 2024
Herein, we report the Ag-catalyzed substrate-controlled interrupted radical pathways of iminyl radical. The benzylic groups played a crucial role in pathway selection involving series dimerization and hydrolysis, 1,5-H shift followed by cascade cyclization, direct N-(sp
Language: Английский
Citations
1