Angewandte Chemie,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 22, 2024
Abstract
Synthetic
organic
electrochemistry
is
recognized
as
one
of
the
most
sustainable
forms
redox
chemistry
that
can
enable
a
wide
variety
useful
transformations.
In
this
study,
readily
prepared
pyrolytic
carbon
electrodes
are
explored
in
several
powerful
rAP
transformations
well
C−C
and
C−N
bond
forming
reactions.
Pyrolytic
provides
an
alternative
to
classic
amorphous
carbon‐based
materials
either
expensive
or
ill‐suited
large‐scale
flow
Green Chemistry,
Journal Year:
2024,
Volume and Issue:
26(10), P. 5824 - 5831
Published: Jan. 1, 2024
An
electrochemical
oxidation-induced
amination
of
simple
alkylarenes
with
sulfoximines
as
a
nitrogen
source
and
5,6-dimethyl-1
H
-benzo[
d
]imidazole
catalyst
was
developed.
Herein,
we
present
a
metal-/catalyst-free,
novel
approach
for
S-sulfoximination
of
sulfenamide.
The
electrooxidative
reactions
sulfenamides
and
sulfoximines
are
fast,
high-yielding,
atom-economical
(99.5%),
broad-substrate-tolerant,
free
from
supporting
electrolytes.
protocol
is
ecofriendly
shows
wider
substrate
tolerance
than
previous
reports.
drug-attached
sulfenamide
(levetiracetam)
sulfoximine
(albendazole)
also
undergo
the
reaction
efficiently.
A
possible
mechanistic
pathway
proposed.
Fascinatingly,
target
products
obtained
via
photochemical
in
presence
photocatalyst
eosin
Y.
Chinese Journal of Chemistry,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Jan. 16, 2025
Comprehensive
Summary
The
N–H
methylsulfoxidation
of
sulfoximines
using
DMSO
as
a
methylsulfinyl
source,
induced
by
electrochemistry,
has
been
developed.
This
method
is
the
first
example
an
electrochemical
reaction
in
which
serves
source.
Unlike
previous
reactions
involving
substrate,
exclusively
proceed
via
radical
mechanisms,
this
follows
S‐cation
pathway.
A
wide
range
N
‐methylsulfinyl
were
successfully
obtained.
Journal of the American Chemical Society,
Journal Year:
2025,
Volume and Issue:
unknown
Published: April 22, 2025
Palladium-catalyzed
bond-forming
reactions
such
as
carbonylations
offer
an
efficient
and
versatile
avenue
to
access
products
from
often
feedstock
reagents.
However,
the
use
of
catalysts
also
comes
with
a
cost,
their
need
be
regenerated
after
each
product-forming
cycle
requires
balancing
thermal
operations.
The
latter
can
lead
high
barriers
even
well
restrict
application
many
products.
We
introduce
herein
alternative
approach
palladium
catalyst
design,
where
instead
electrochemical
potential
drive
catalysis
by
continual
two-electron
cycling
metal
oxidation
state.
power
behind
these
redox
steps
offers
route
carry
out
carbonylation
reactions,
including
catalytic
synthesis
high-energy
aroyl
halide
electrophiles,
at
unprecedentedly
mild
ambient
temperature
pressure.
More
generally,
analysis
suggests
this
functions
distinct
multi-electron
exchange
pathway,
reduction
enables
oxidative
addition
drives
product
elimination.
combination
creates
unique
platform
both
reverse
operations
are
favored
in
same
system
energy
only
added
source.
The Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
89(9), P. 6106 - 6116
Published: April 18, 2024
An
electrochemical
oxidative
cross-coupling
strategy
for
the
synthesis
of
N-sulfenylsulfoximines
from
sulfoximines
and
thiols
was
accomplished,
giving
diverse
in
moderate
to
good
yields.
Moreover,
this
can
be
extended
construct
N–P
bond
N-phosphinylated
sulfoximines.
With
electrons
as
reagents,
dehydrogenation
reaction
proceeds
smoothly
absence
traditional
redox
reagents.
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
unknown
Published: Oct. 25, 2024
Abstract
Synthetic
organic
electrochemistry
is
recognized
as
one
of
the
most
sustainable
forms
redox
chemistry
that
can
enable
a
wide
variety
useful
transformations.
In
this
study,
readily
prepared
pyrolytic
carbon
electrodes
are
explored
in
several
powerful
rAP
transformations
well
C−C
and
C−N
bond
forming
reactions.
Pyrolytic
provides
an
alternative
to
classic
amorphous
carbon‐based
materials
either
expensive
or
ill‐suited
large‐scale
flow
Organic & Biomolecular Chemistry,
Journal Year:
2024,
Volume and Issue:
22(29), P. 5907 - 5912
Published: Jan. 1, 2024
An
electrochemically
promoted
oxidative
dehydrogenation
cross-coupling
reaction
between
aldehyde
hydrazones
and
thiophenols
is
demonstrated
for
the
first
time,
which
results
in
a
variety
of
thioetherified
products
moderate
to
excellent
yields.
