Controllable Tertiary Amines-Promoted Photoactivation Metal-Free Carbonylation of Aryl Sulfonium Salts to Aryl Carboxylic Acid Derivatives DOI Creative Commons
Jiajun Zhang,

Le‐Cheng Wang,

Yuanrui Wang

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 26(23), P. 11686 - 11694

Published: Jan. 1, 2024

This paper describes a new method for the activation of aryl radicals via EDA complexes without metals and photosensitizers carbonylation with various nucleophilic reagents under visible light.

Language: Английский

Standardized Approach for Diversification of Complex Small Molecules via Aryl Thianthrenium Salts DOI Creative Commons
Dilgam Ahmadli, Sven Müller, Yuanhao Xie

et al.

Journal of the American Chemical Society, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 21, 2025

Thianthrenation is a useful strategy for the late-stage diversification of complex small molecules owing to positional selectivity and synthetic versatility thianthrenium salts as electrophilic linchpins. However, substrate-dependent identification suitable reaction conditions thianthrenation can be difficult. Reported functionalization vary significantly and, in some instances, lack robustness practicality. Herein, we report generalized approach preparation two manifolds practical, robust, parallel salts.

Language: Английский

Citations

2
Palladium-Catalyzed Cross-Electrophile Couplings of Aryl Thianthrenium Salts with Aryl Bromides via C–S Bond Activation DOI

Qian-Qian Fu,

Liang Yuan, Xiaoxiao Sun

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 30, 2024

We report here a step-economic and cost-effective cross-electrophile coupling of aryl thianthrenium salts with widely available bromides, which proceeded effectively via C-S bond activation at ambient temperature in THF the presence palladium catalyst, magnesium turnings, lithium chloride to enable facile assembly wide array structurally diverse biaryls modest good yields functional group compatibility. In addition, gram-scale reaction could also be realized.

Language: Английский

Citations

4
Palladium‐Catalyzed Carbonylative Sonogashira Transformations: Advancements and Insights DOI Open Access

Prasad Vishnu,

Padinjare Veetil Saranya,

Gopinathan Anilkumar

et al.

The Chemical Record, Journal Year: 2025, Volume and Issue: unknown

Published: March 27, 2025

Abstract Palladium‐catalyzed carbonylative reactions, used as a tool for the insertion of carbonyl group into organic moieties, is synthetically useful transformation. Carbonylative Sonogashira coupling convenient approach synthesis α,β‐acetylenic ketones which are important class molecules in pharmaceutical and industrial fields. Development greener approaches environmentally benign catalytic systems put forward enormous opportunities this field moreover, these researches indicate formation heterocycles via carbonylation strategy, major highlight. Herein, we discuss progress achieved palladium‐catalyzed from 2013 to 2024 its future prospects.

Language: Английский

Citations

0
Palladium-catalyzed Narasaka–Heck carbonylation for the construction of functionalized ynones DOI
Ming Li, Fei Yang,

Shan-Mei Xu

et al.

Chemical Communications, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Pd-catalyzed Narasaka–Heck carbonylation efficiently synthesizes functionalized alkynones (70% yield) under mild conditions. This strategy offers a multifunctional platform for bioactive molecule construction in medicinal chemistry.

Language: Английский

Citations

0
Palladium-catalyzed carbene C–H insertion reaction of non-activated arenes DOI
Shihaozhi Wang, Jiahui Shi,

Shan Xu

et al.

Chinese Chemical Letters, Journal Year: 2025, Volume and Issue: unknown, P. 111225 - 111225

Published: April 1, 2025

Language: Английский

Citations

0
Palladium-Catalyzed Carbonylative Sonogashira Coupling of Aliphatic Alkynes and Aryl Thianthrenium Salts to Alkynones and Furanones DOI Creative Commons
Yanhua Zhao,

Xing‐Wei Gu,

Xiao‐Feng Wu

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 9, 2024

Herein, we developed a mild and efficient palladium-catalyzed carbonylative Sonogashira coupling of aryl thianthrenium salts with aliphatic alkynes benzyl acetylene toward alkynones furanones. Various desired products were prepared in good yields broad functional group tolerance including the bromide group. In case using acetylene, corresponding furanones can be obtained under same conditions two molecules CO inserted.

Language: Английский

Citations

2
Controllable Tertiary Amines-Promoted Photoactivation Metal-Free Carbonylation of Aryl Sulfonium Salts to Aryl Carboxylic Acid Derivatives DOI Creative Commons
Jiajun Zhang,

Le‐Cheng Wang,

Yuanrui Wang

et al.

Green Chemistry, Journal Year: 2024, Volume and Issue: 26(23), P. 11686 - 11694

Published: Jan. 1, 2024

This paper describes a new method for the activation of aryl radicals via EDA complexes without metals and photosensitizers carbonylation with various nucleophilic reagents under visible light.

Language: Английский

Citations

0