Electrochemical strategies for N-cyanation of secondary amines and α C-cyanation of tertiary amines under transition metal-free conditions DOI
Zhengjiang Fu,

Yaping Fu,

Jian Dong Yin

et al.

Green Chemistry, Journal Year: 2021, Volume and Issue: 23(23), P. 9422 - 9427

Published: Jan. 1, 2021

Electrochemical N -cyanation of secondary amines and α C tertiary have been established under transition metal-free conditions, which provide cyanamides nitriles with good functional group tolerance from simple systems.

Language: Английский

Recent Advances in C(sp3)—H Phosphorylation Based on Secondary Phosphine Oxides and Phosphite Esters DOI Open Access

Yuanting Huang,

Qian Chen

Chinese Journal of Organic Chemistry, Journal Year: 2021, Volume and Issue: 41(11), P. 4138 - 4138

Published: Jan. 1, 2021

Organophosphorus compounds bearing C(sp 3 )-P bonds have been widely used in organic synthesis, bioorganic and medical chemistry, agrochemicals, flame retardants extractants.In recent years, the direct phosphorylation of C-H has received much attention because this strategy represents more straightforward, efficient atom-economic construction C-P bonds.The advances )-H using secondary phosphine oxides phosphite esters as phosphorus sources since 2009 are reviewed, corresponding reactions categorized five types according to structure bonds.

Language: Английский

Citations

22
Recent advances in the electrochemical reactions of nitrogen-containing organic compounds DOI Creative Commons
Babak Kaboudin, Milad Behroozi,

Sepideh Sadighi

et al.

RSC Advances, Journal Year: 2022, Volume and Issue: 12(47), P. 30466 - 30479

Published: Jan. 1, 2022

The electrochemical reaction of amines, nitriles, amides, nitroaromatics, and imines has been proven to be a valuable method for the synthesis various nitrogen-containing organic compounds.

Language: Английский

Citations

15
Direct Phosphonylation of N-Carbamate-tetrahydroisoquinoline by Convergent Paired Electrolysis DOI
Stéphane Sengmany, Thierry Martens,

Anthony Ollivier

et al.

Synlett, Journal Year: 2020, Volume and Issue: 31(12), P. 1191 - 1196

Published: April 17, 2020

Mild experimental conditions for a direct phosphonylation of an easily cleavable N-carbamate-tetrahydroisoquinoline have been described under constant current electrolysis. The developed electrochemical process allowed to prepare α-aminophosphonates in moderate good yields. On the basis results, mechanism proceeding through convergent paired was enabled be postulated.

Language: Английский

Citations

21
Electrochemical 2,2,6,6-tetramethylpiperidinyl-N-oxyl (TEMPO)-Mediated α-Cyanation and Phosphonylation of Cyclic Amines with Metal-Free Conditions DOI Open Access

Jun-Qing Gao,

Xin‐Jun Weng,

Cong Ma

et al.

Chinese Journal of Organic Chemistry, Journal Year: 2021, Volume and Issue: 41(8), P. 3223 - 3223

Published: Jan. 1, 2021

Metal-free electrochemical oxidation cyanation and phosphonylation reactions had been developed, in which 2,2,6,6-tetramethylpiperidinyl-N-oxyl (TEMPO) reduced the electrode potential of substrate avoided over some electron rich aromatic amines under conditions.This protocol good functional group compatibility, made it to be a practical efficient method synthesize α-aminonitriles α-amino phosphonates mild conditions.Preliminary study indicated that formation product was through Shono imine species.

Language: Английский

Citations

20
Electrochemical strategies for N-cyanation of secondary amines and α C-cyanation of tertiary amines under transition metal-free conditions DOI
Zhengjiang Fu,

Yaping Fu,

Jian Dong Yin

et al.

Green Chemistry, Journal Year: 2021, Volume and Issue: 23(23), P. 9422 - 9427

Published: Jan. 1, 2021

Electrochemical N -cyanation of secondary amines and α C tertiary have been established under transition metal-free conditions, which provide cyanamides nitriles with good functional group tolerance from simple systems.

Language: Английский

Citations

19