Hermetic microfluidic device for point-of-care viral nucleic acid testing DOI
Jie Hu, Hao Bai, Lei Wang

et al.

Sensors and Actuators B Chemical, Journal Year: 2024, Volume and Issue: 411, P. 135740 - 135740

Published: April 1, 2024

Language: Английский

Rapid assays of SARS-CoV-2 virus and noble biosensors by nanomaterials DOI Creative Commons
Yang Liu, Yilong Li,

Yuteng Hang

et al.

Nano Convergence, Journal Year: 2024, Volume and Issue: 11(1)

Published: Jan. 8, 2024

Abstract The COVID-19 outbreak caused by SARS-CoV-2 in late 2019 has spread rapidly across the world to form a global epidemic of respiratory infectious diseases. Increased investigations on diagnostic tools are currently implemented assist rapid identification virus because mass and diagnosis might be best way prevent virus. This critical review discusses detection principles, fabrication techniques, applications with three categories: nuclear acid augmentation test, immunoassay test biosensors. Special efforts were put enhancement nanomaterials biosensors for rapid, sensitive, low-cost diagnostics Future developments suggested regarding potential candidates hospitals, clinics laboratories control prevention large-scale epidemic. Graphical

Language: Английский

Citations

15

Internet-of-things-integrated molecularly imprinted polymer-based electrochemical nano-sensors for pesticide detection in the environment and food products DOI
Arpana Parihar,

Palak Sharma,

Nishant Kumar Choudhary

et al.

Environmental Pollution, Journal Year: 2024, Volume and Issue: 351, P. 124029 - 124029

Published: April 23, 2024

Language: Английский

Citations

11

Applications of microfluidics in biosensing DOI Creative Commons

Masindi Sekhwama,

Kelvin Mpofu, Sudesh Sivarasu

et al.

Deleted Journal, Journal Year: 2024, Volume and Issue: 6(6)

Published: May 31, 2024

Abstract Microfluidic devices have become a vastly popular technology, particularly because of the advantages they offer over their traditional counterparts. They such wide range uses and can make complex tasks quite efficient. One area research or work that has benefited greatly from use microfluidics is biosensing, where microfluidic chips are integrated into biosensor setups. There growing numbers applications in this as researchers look for efficient ways to tackle disease diagnostics drug discovery, which critical era recurring pandemics. In work, authors review integration with biosensors, well food security, molecular biology, cell diagnostics, at some most recent these areas. The covers including cellular life science research, agro-food processing, immunological veterinarian diagnostics. Microfluidics field combines fundamental laws physics chemistry solve miniaturization problems involving fluids nanoscale microscale, such, also examine mathematical concepts biosensing. relatively new technologies great potential terms applications.

Language: Английский

Citations

9

3D printed human organoids: High throughput system for drug screening and testing in current COVID‐19 pandemic DOI
Arpana Parihar,

Vasundhara Pandita,

Raju Khan

et al.

Biotechnology and Bioengineering, Journal Year: 2022, Volume and Issue: 119(10), P. 2669 - 2688

Published: June 29, 2022

In the current pandemic, scenario world is facing a huge shortage of effective drugs and other prophylactic medicine to treat patients which created havoc in several countries with poor resources. With limited demand supply drugs, researchers rushed repurpose existing approved for treatment COVID-19. The process drug screening testing very costly requires steps validation efficacy evaluation ranging from in-vitro in-vivo setups. After these steps, clinical trial mandatory side effects humans. These processes enhance overall cost sometimes lead molecule show adverse humans ends up final stages. Recently advent three-dimensional (3D) organoid culture mimics human tissue exactly can be done faster cost-effective manner. Further 3D organoids prepared stems cells taken individuals beneficial personalized therapy could save millions lives. This review discussed approaches techniques synthesis 3D-printed screening. key findings usage COVID-19 have been discussed. end, challenges wide applicability prospects future orientation included.

Language: Английский

Citations

30

Enzyme-immobilized microfluidic devices for biomolecule detection DOI
Hiroshi Yamaguchi, Masaya Miyazaki

TrAC Trends in Analytical Chemistry, Journal Year: 2022, Volume and Issue: 159, P. 116908 - 116908

Published: Dec. 29, 2022

Language: Английский

Citations

29

Towards sense and sensitivity-based electrochemical biosensors for liquid biopsy-based breast cancer detection DOI
Sima Singh, Antonella Miglione, Ada Raucci

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 163, P. 117050 - 117050

Published: April 6, 2023

Language: Английский

Citations

21

Two birds with one stone: A multifunctional nanoplatform for photothermal sensitive detection and real-time inactivation of Staphylococcus aureus with NIR responsive Cu2−XSe@Van NPs DOI
Xiaodong Lin, Bergoi Ibarlucea, Peng Tao

et al.

Sensors and Actuators B Chemical, Journal Year: 2023, Volume and Issue: 381, P. 133475 - 133475

Published: Feb. 4, 2023

Language: Английский

Citations

20

Dual-channel MIRECL portable devices with impedance effect coupled smartphone and machine learning system for tyramine identification and quantification DOI
Zhiwei Lu, Jun Qin, Wu Chun

et al.

Food Chemistry, Journal Year: 2023, Volume and Issue: 429, P. 136920 - 136920

Published: July 20, 2023

Language: Английский

Citations

19

Advances in Microfluidic Systems and Numerical Modeling in Biomedical Applications: A Review DOI Creative Commons

Mariana Ferreira,

Violeta Carvalho, João Ribeiro

et al.

Micromachines, Journal Year: 2024, Volume and Issue: 15(7), P. 873 - 873

Published: June 30, 2024

The evolution in the biomedical engineering field boosts innovative technologies, with microfluidic systems standing out as transformative tools disease diagnosis, treatment, and monitoring. Numerical simulation has emerged a tool of increasing importance for better understanding predicting fluid-flow behavior microscale devices. This review explores fabrication techniques common materials devices, focusing on soft lithography additive manufacturing. Microfluidic applications, including nucleic acid amplification protein synthesis, well point-of-care diagnostics, DNA analysis, cell cultures, organ-on-a-chip models (e.g., lung-, brain-, liver-, tumor-on-a-chip), are discussed. Recent studies have applied computational such ANSYS Fluent 2024 software to numerically simulate flow behavior. Outside study cases, this work reports fundamental aspects simulations, fluid flow, mass transport, mixing, diffusion, highlights emergent simulations. Additionally, it takes into account application geometries improve mixing samples, surface wettability modification. In conclusion, present summarizes most relevant contributions their numerical modeling engineering.

Language: Английский

Citations

7

Microfluidic-based technologies for diagnosis, prevention, and treatment of COVID-19: recent advances and future directions DOI Open Access
E. Alperay Tarim, Müge Anıl-İnevi,

Ilayda Ozkan

et al.

Biomedical Microdevices, Journal Year: 2023, Volume and Issue: 25(2)

Published: March 13, 2023

Language: Английский

Citations

16