MXene-based aptasensor for the detection of aflatoxin in food and agricultural products

Environmental Pollution, Journal Year: 2022, Volume and Issue: 316, P. 120695 - 120695

Published: Nov. 21, 2022

Language: Английский

---

Internet‐of‐medical‐things integrated point‐of‐care biosensing devices for infectious diseases: Toward better preparedness for futuristic pandemics

Bioengineering & Translational Medicine, Journal Year: 2023, Volume and Issue: 8(3)

Published: Jan. 3, 2023

Abstract Microbial pathogens have threatened the world due to their pathogenicity and ability spread in communities. The conventional laboratory‐based diagnostics of microbes such as bacteria viruses need bulky expensive experimental instruments skilled personnel which limits usage resource‐limited settings. biosensors‐based point‐of‐care (POC) shown huge potential detect microbial a faster, cost‐effective, user‐friendly manner. use various transducers electrochemical optical along with microfluidic integrated biosensors further enhances sensitivity selectivity detection. Additionally, microfluidic‐based offer advantages multiplexed detection analyte deal nanoliters volume fluid an portable platform. In present review, we discussed design fabrication POCT devices for include bacteria, viruses, fungi, parasites. techniques current advances this field terms platforms that mainly microfluidic‐ based approaches smartphone Internet‐of‐things (IoT) Internet‐of‐Medical‐Things (IoMT) systems been highlighted. Further, availability commercial will be briefed. end, challenges while POC expected future biosensing discussed. biosensor‐based IoT/IoMT usually collect data track community infectious diseases would beneficial better preparedness futuristic pandemics is prevent social economic losses.

Language: Английский

---

Revolutionizing Disease Modeling: The Emergence of Organoids in Cellular Systems

Cells, Journal Year: 2023, Volume and Issue: 12(6), P. 930 - 930

Published: March 18, 2023

Cellular models have created opportunities to explore the characteristics of human diseases through well-established protocols, while avoiding ethical restrictions associated with post-mortem studies and costs researching animal models. The capability cell reprogramming, such as induced pluripotent stem cells (iPSCs) technology, solved complications embryonic (hESC) usage. Moreover, iPSCs made significant contributions for medicine, in diagnosis, therapeutic regenerative medicine. two-dimensional (2D) allowed monolayer cellular culture vitro; however, they were surpassed by three-dimensional (3D) system. 3D provides higher cell–cell contact a multi-layered culture, which more closely respects morphology polarity. It is tightly able resemble conditions vivo closer approach architecture tissues, organoids. Organoids are structures that mimic function native tissues. They generated vitro from or differentiated cells, epithelial neural used study organ development, disease modeling, drug discovery. become powerful tool understanding molecular mechanisms underlying physiology, providing new insights into pathogenesis cancer, metabolic diseases, brain disorders. Although organoid technology up-and-coming, it also has some limitations require improvements.

Language: Английский

---

Cryopreservation: A Comprehensive Overview, Challenges, and Future Perspectives

Advanced Biology, Journal Year: 2023, Volume and Issue: 7(6)

Published: Feb. 8, 2023

Abstract Cryopreservation is the most prevalent method of long‐term cell preservation. Effective cryopreservation depends on freezing, adequate storage, and correct thawing techniques. Recent advances in techniques minimize cellular damage which occurs while processing samples. This article focuses fundamentals how they can be implemented a variety clinical settings. The presents brief description each standard procedures, such as slow freezing vitrification. Alongside that, membrane permeating nonpermeating cryoprotectants are briefly discussed, along with current advancements field variables influencing process. diminution cryoinjury incurred by via resuscitation process will also highlighted. In end application many fields, special emphasis stem preservation presented. Furthermore, challenges implementing futuristic scope fields illustrated herein. content this review sheds light various ways to enhance output improving revival.

Language: Английский

---

Three-Dimensional Bioprinting of Organoids: Past, Present, and Prospective

Tissue Engineering Part A, Journal Year: 2024, Volume and Issue: 30(11-12), P. 314 - 321

Published: Jan. 11, 2024

Organoids are three-dimensional (3D)

Language: Английский

---

Research progress on anti-stress nutrition strategies in swine

Animal nutrition, Journal Year: 2023, Volume and Issue: 13, P. 342 - 360

Published: April 6, 2023

In swine production, stress is a common encounter that leads to serious bacterial infection and adverse effects on growth performance. Though antibiotics have been frequently used control pathogen spread, sustained negative impacts from found affect intestinal integrity the immune system. Multiple nutritional strategies shown potential counteract replace antibiotics, including functional amino acids, low protein diet, plant extracts, organic prebiotics, probiotics, minerals vitamins. These additives relieve response in via different mechanisms signal transduction pathways. Based overview of signaling pathways models, this review highlights for preventing or treating stress-related health problems. For wider application pig industry, dose ranges measured require further validation physiological contexts formulations. future, microfluid devices novel models are expected enhance efficiency screening new anti-stress candidates.

Language: Английский

---

Green Synthesis of CdS and CdS/rGO Nanocomposites: Evaluation of Electrochemical, Antimicrobial, and Photocatalytic Properties

ACS Applied Bio Materials, Journal Year: 2023, Volume and Issue: 6(9), P. 3706 - 3716

Published: Sept. 7, 2023

The green approach has been employed for the synthesis of various types nanomaterials including metal nanoparticles, oxides, and carbon-based nanomaterials. These processes involve natural sources that contain bioactive compounds act as reducing, stabilizing, capping agents formation stabilization This study reports CdS CdS/rGO nanocomposites using Lactobacillus bacteria. UV-visible spectrophotometer, field emission scanning electron microscopy, transmission energy-dispersive X-ray spectroscopy, Raman Fourier transform infrared spectroscopy spectra confirm nanocomposite. electrochemical characterization cyclic voltammetry, differential pulse EIS revealed showed a higher transfer rate compared with indicating potential biosensing applications. zone inhibition significant antimicrobial activity against Escherichia coli Staphylococcus aureus both nanoparticles nanocomposites. Additionally, exhibited high photocatalytic degradation methylene blue dye. Overall, this demonstrates synthesized have good properties, photocatalytic, and, therefore, can be applications such biosensing, photocatalysis, activity.

Language: Английский

---

Miniaturized MXene-based electrochemical biosensors for virus detection

Bioelectrochemistry, Journal Year: 2024, Volume and Issue: 158, P. 108700 - 108700

Published: April 2, 2024

Language: Английский

---

Advances in organoid-on-a-chip for recapitulation of human physiological events

Materials Today, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 1, 2025

Language: Английский

---

Enhanced sphericity and uniformity in adenocarcinoma spheroids on chip via fibroblast Co-Culture for electrochemical drug screening

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 162547 - 162547

Published: April 1, 2025

Language: Английский

---