Material Technologies for Improved Diabetic Foot Ulcer (DFU) Treatment: A Questionnaire Study of Healthcare Professionals’ Needs DOI Creative Commons
M. Guerrero, Lieve Vonken, E J Peters

et al.

Biomedicines, Journal Year: 2024, Volume and Issue: 12(11), P. 2483 - 2483

Published: Oct. 29, 2024

Diabetic foot ulcers (DFUs) are a common and severe complication of diabetic patients, with significant global prevalence associated health burdens, including high recurrence rates, lower-limb amputations, substantial economic costs. This study aimed to understand the user needs healthcare professionals treating for newly developed material technologies.

Language: Английский

Research progress of natural polysaccharide-based and natural protein-based hydrogels for bacteria-infected wound healing DOI

XU Hui-qing,

Yilin Che,

Rui Zhou

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 496, P. 153803 - 153803

Published: July 6, 2024

Language: Английский

Citations

18
Advancements in Wound Dressing Materials: Highlighting Recent Progress in Hydrogels, Foams, and Antimicrobial Dressings DOI Creative Commons

A. S. Alberts,

Dana-Ionela Tudorache,

Adelina-Gabriela Niculescu

et al.

Gels, Journal Year: 2025, Volume and Issue: 11(2), P. 123 - 123

Published: Feb. 7, 2025

Recent advancements in wound dressing materials have significantly improved acute and chronic management by addressing challenges such as infection control, moisture balance, enhanced healing. Important progress has been made, especially with hydrogels, foams, antimicrobial for creating optimized dressings. Hydrogels are known maintaining optimal levels, while foam dressings excellent exudate absorbents. Meanwhile, incorporates various agents to reduce risks. These options healing time focusing on customized patient needs. Therefore, this review highlights the newest research prototypes applications, emphasizing their particular benefits clinical importance. Innovations stimuli-responsive hydrogels hybrid bioengineered composites discussed relation properties, including responsiveness pH, temperature, glucose, or enzymes drug delivery precision. Moreover, ongoing trials included, demonstrating potential of emerging solutions be soon translated from laboratory settings. By discussing interdisciplinary approaches that integrate advanced materials, nanotechnology, biological insights, work provides a contemporary framework patient-centric, efficient care strategies.

Language: Английский

Citations

4
Sustainable dressings for wound healing DOI Creative Commons
Munishwar N. Gupta,

Avinash Rangaraju,

Premlata Ambre

et al.

Deleted Journal, Journal Year: 2025, Volume and Issue: 2(1)

Published: Jan. 2, 2025

Abstract The field of chronic wound care has been rapidly evolving. With a market size for wounds in billions USD, this is not an insignificant area to encourage more sustainable practices and processes. sourcing starting materials dressings from renewable resources the first crucial step ensuring that environmental impact minimized. Next important choice select methodologies accordance with principles green chemistry. This involves utilizing solvents as reaction media chemical processes preparing dressing materials. In many cases, like production hydrogels, crosslinking reagents are often employed. These can be, general, easily replaced by enzymes peroxidases, tyrosinases sortases. Process intensification strategies have emerged powerful approach ensure economy sustainability at large scale. Use microwave radiations ultrasonication instead heat accelerate rates helps cases inject wounds. review attempts highlight ongoing efforts future possibilities development cost-effective methods. Graphical

Language: Английский

Citations

1
Thermal-responsive microgels incorporated PVA composite hydrogels: Integration of two-stage drug release and enhanced self-healing ability for chronic wound treatment DOI
Zeying Liu, Huixia Li, Yuyu Huang

et al.

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159813 - 159813

Published: Jan. 1, 2025

Language: Английский

Citations

1
Biopolymer hydrogels and synergistic blends for tailored wound healing DOI

Yasamin Haririan,

Azadeh Asefnejad

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 279, P. 135519 - 135519

Published: Sept. 10, 2024

Language: Английский

Citations

6
Advances in the development of medical dressings for the treatment of diabetic foot wounds DOI
Ming Cai, Zhao Liu,

Xun Sun

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 498, P. 155575 - 155575

Published: Sept. 7, 2024

Language: Английский

Citations

5
Optimizing alginate dressings with allantoin and chemical modifiers to promote wound healing DOI

Haichao Zhu,

Hoi Tong Ao,

Yuli Fu

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 275, P. 133524 - 133524

Published: June 28, 2024

Language: Английский

Citations

4
Bacteria-Derived Cellulose Membranes Modified with Graphene Oxide-Silver Nanoparticles for Accelerating Wound Healing DOI Creative Commons
Érika Patrícia Chagas Gomes Luz, Thamyres Freire da Silva, Lidyane Souto Maciel Marques

et al.

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: 7(8), P. 5530 - 5540

Published: Aug. 2, 2024

This study reports on the modification of bacterial cellulose (BC) membranes produced by static fermentation

Language: Английский

Citations

4
Computational Elucidation of Human β-Defensin-2 as a Dual Inhibitor of MMP-9 and PKC-βII for Diabetic Wound Management DOI Creative Commons
Vidyasrilekha Yele, Dilep Kumar Sigalapalli, Afzal B. Shaik

et al.

ACS Omega, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 26, 2025

Diabetic wounds (DWs) are the most devastating complication, resulting in significant mortality and morbidity diabetic patients. Although pathophysiology of DWs is multifaceted, evidence has revealed that prolonged inflammation with infections, extracellular matrix (ECM) degradation, unnecessary NETosis impair DW healing. This theoretical problem highlights necessity developing a novel strategy focused on targeting "specific" molecular modalities DWs. The primary culprits, metalloproteinase (MMP)-9 protein kinase C (PKC)-βII, responsible for impaired angiogenesis, NETosis, ECM degradation. Thus, interest identifying selective inhibitors effective management increased. current study exemplified human β-defensin-2 (HBD-2), biological macromolecule functions as dual inhibitor MMP-9 PKC-βII, via protein-protein docking dynamics simulation studies. Overall, data analysis HBD-2 possesses strong binding affinity stability against suggesting may be an ideal therapeutic accelerated healing DW. Our findings suggest HBD-2's potential innovative healing, offering valuable insights into its mechanisms. However, vitro vivo studies required to bridge gap between computational modeling clinical application.

Language: Английский

Citations

0
Optically pH-Sensing in Smart Wound Dressings Towards Real-time Monitoring of Wound States: A Review DOI

Hongchun Gu,

Xinxing Sun,

Hongyang Bao

et al.

Analytica Chimica Acta, Journal Year: 2025, Volume and Issue: 1350, P. 343808 - 343808

Published: Feb. 16, 2025

Language: Английский

Citations

0