Biomedical applications of supramolecular hydrogels with enhanced mechanical properties

Advances in Colloid and Interface Science, Journal Year: 2023, Volume and Issue: 321, P. 103000 - 103000

Published: Sept. 20, 2023

Language: Английский

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A supramolecular hydrogel dressing with antibacterial, immunoregulation, and pro-regeneration ability for biofilm-associated wound healing

Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 368, P. 740 - 755

Published: March 19, 2024

Language: Английский

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Novel Lignin Hydrogel Sensors with Antiswelling, Antifreezing, and Anticreep Properties

ACS Sustainable Chemistry & Engineering, Journal Year: 2023, Volume and Issue: 11(22), P. 8255 - 8270

Published: May 22, 2023

Hydrogel shows great potential as a flexible wearable electronic device. However, the practical application of hydrogel is still significantly limited due to poor functional stability caused by swelling behavior, non-frost resistance high water content, and obvious creep behavior under repeated external force. In this work, macromolecular lignin with three-dimensional network structure, active groups are introduced into through esterification grafting reaction methacryloyl chloride. The introduction effectively improves antiswelling, antifreezing, sensor, while maintaining mechanical properties (elongation at break > 350%, tensile strength 1.5 MPa) electrical conductivity (10 S/m). Under extreme environments, toughness, strength, elongation remain more than 96%. Furthermore, resistance, sensors not affected after immersion in for long time (72 h). This work proposes simple strategy improve anticreep hydrogels, which has guiding significance preparation high-performance materials.

Language: Английский

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Structurally dynamic self-healable hydrogel cooperatively inhibits intestinal inflammation and promotes mucosal repair for enhanced ulcerative colitis treatment

Biomaterials, Journal Year: 2023, Volume and Issue: 299, P. 122184 - 122184

Published: May 31, 2023

Language: Английский

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“Deep Eutectic Solvent-in-Water” Hydrogels Enable High-Performance Flexible Strain Sensors for Electronic Skin with a Wide Operating Temperature Range

ACS Sustainable Chemistry & Engineering, Journal Year: 2023, Volume and Issue: 11(28), P. 10578 - 10589

Published: July 6, 2023

Conductive hydrogels have become one of the hot topics in flexible strain sensors owing to excellent biocompatibility, attractive mechanical flexibilities, and conductive properties. However, time-consuming preparation their unsuitable properties limit application low-temperature environment high temperatures. Here, a new class "deep eutectic solvent-in-water" (DIWHs) is reported for first time through one-step gelation process situ without solvent displacement, fabricated by combining hydrogel with deep (DES). The DIWH constructed using dynamic oxidation coordination system composed sodium lignosulfonate (Ls) Fe3+. effect DES optimal mass ratio water on was synthetically investigated. addition not only shortens polymerization 8 s enhances but also provides some unique For example, gives gels greater self-healing ability antibacterial When 1:3, antifreezing antidrying were imparted gel, elasticity maintained even at −80 °C or stored 60 7 days. Furthermore, exhibited strong interfacial adhesion natural synthetic materials (up kPa glass) due presence Ls catechol structure. In conclusion, this work stimulates more interest sustainable high-value utilization fully demonstrates advantages easy-to-prepare coacervation gel sensing.

Language: Английский

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Application of supramolecular hydrogel in supercapacitors: Opportunities and challenges

Aggregate, Journal Year: 2024, Volume and Issue: 5(5)

Published: May 15, 2024

Abstract Supercapacitors (SCs) are studied and used in various fields due to their high power density, fast charging/discharging rate, as well long cycle life. Compared other traditional electrode electrolyte materials, supramolecular hydrogels have great advantages the application of SCs excellent properties. Unlike covalent bonds, systems assembled through dynamic reversible including host–guest interactions, ion electrostatic hydrogen bonding, coordination etc. The resulting show some special functions, such stretching, compression, adhesion, self‐healing, stimulus responsiveness, etc., making them strong candidates for next generation energy storage devices. This paper reviews representative progress electrodes, electrolytes, based on hydrogels. Besides, properties hydrogels, conductivity, extensibility, compressibility elasticity, frost resistance, flexibility, also reviewed highlight key role hydrogel materials SCs. In addition, this article discusses challenges faced by current technologies, hoping continue promoting future research field.

Language: Английский

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Tannic acid modified keratin/sodium alginate/carboxymethyl chitosan biocomposite hydrogels with good mechanical properties and swelling behavior

Scientific Reports, Journal Year: 2024, Volume and Issue: 14(1)

Published: June 4, 2024

Natural polymer-based hydrogels have demonstrated great potential as wound-healing dressings. They help to maintain a moist wound environment well promote faster healing. In this work, multifunctional hydrogel was prepared using keratin, sodium alginate, and carboxymethyl chitosan with tannic acid modification. Micro-morphology of has been performed by scanning electron microscopy. Fourier Transform Infrared Spectroscopy reveals the presence hydrogen bonding. The mechanical properties were examined universal testing machine. Furthermore, we investigated several modified hydrogel. These include swelling rate, water retention, anti-freezing properties, antimicrobial antioxidant hemocompatibility evaluation cell viability test in vitro. three-dimensional microporous structure, rate 1541.7%, elastic modulus 589.74 kPa, toughness 211.74 kJ/m

Language: Английский

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Highly hydrophobic cotton fabric by in-situ co-deposition of lignin/metal particles for oil/water separation

Industrial Crops and Products, Journal Year: 2023, Volume and Issue: 204, P. 117393 - 117393

Published: Sept. 4, 2023

Language: Английский

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Quaternary Pullulan-Functionalized 2D MoS₂ Glycosheets: A Potent Bactericidal Nanoplatform for Efficient Wound Disinfection and Healing

ACS Applied Materials & Interfaces, Journal Year: 2023, Volume and Issue: 15(20), P. 24209 - 24227

Published: May 11, 2023

Rapid emergence of multidrug-resistant bacterial strains has posed a global threat to public health. Hospital-acquired infections, especially in diabetic and burn patients, severely impede the process wound healing, thereby causing high mortality. This calls for developing new biomaterial that synergistically destroys pathogenic also helps promoting healing without any resistance generation. A highly potent antibacterial agent been developed by integrating bactericidal properties MoS2 nanosheets recently quaternized polysaccharide, pullulan (CP), into single nanoplatform accelerated therapy. are noncovalently functionalized with yield glycosheets (MCP) efficiently eradicate both Gram-negative Escherichia coli (5 μg/mL) Gram-positive Staphylococcus aureus (10 within short period 4 h, through synergistic action membrane damage chemical oxidation. coupled CP exert membrane-directed distinct mechanisms "pore-forming" "non-pore-forming" pathways, respectively, whereas oxidative stress is induced alone collectively kill pathogens. The MCP have good biocompatibility capable disrupting eradicating mature biofilms. efficient vivo disinfection occurred upon treatment reduction inflammation promotion cellular proliferation tissue remodeling. Thus, can emerge as safe potential better care management.

Language: Английский

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Lignin-containing hydrogels: Transforming a low-value byproduct to absorbents, wound dressings and strain sensors

Chemical Engineering Journal, Journal Year: 2023, Volume and Issue: 475, P. 146460 - 146460

Published: Oct. 5, 2023

Language: Английский

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