Nanosheet-assembled porous-wall hollow hydroxyapatite microspheres prepared by a template-free hydrothermal method for pH-responsive drug release DOI

Wei‐li Xu,

Yu‐peng Lu,

Gui‐yong Xiao

et al.

Ceramics International, Journal Year: 2024, Volume and Issue: 50(22), P. 47501 - 47506

Published: Sept. 3, 2024

Language: Английский

Green engineered biomaterials for bone repair and regeneration: Printing technologies and fracture analysis DOI
Balbina Makurat‐Kasprolewicz, Hossein Ipakchi,

Pouya Rajaee

et al.

Chemical Engineering Journal, Journal Year: 2024, Volume and Issue: 494, P. 152703 - 152703

Published: June 5, 2024

Language: Английский

Citations

11
Flexible Short Silica Fibers and Tricalcium Phosphate Synergistically Promote Bone Fracture Healing in Composite Cryogel Scaffolds DOI Open Access
Xinyi Wang, Zhengchao Yuan,

Guangfang Cai

et al.

Advanced Healthcare Materials, Journal Year: 2025, Volume and Issue: unknown

Published: Feb. 27, 2025

Bone tissue engineering is a critical area of research focused on enhancing the regeneration bone tissue, particularly in cases complex defects. Despite inherent self-healing capabilities bone, irregularly-shaped defects pose significant challenges for complete regeneration, thereby necessitating innovative therapeutic strategies. This study addresses these by exploring development advanced scaffolds. Here, tricalcium phosphate (TCP) integrated with short silica (SiO2) fibers to develop 3D cryogel scaffolds, designated as SSFx@TCP. These scaffolds exhibit low density (<2 mg cm- 3), high water absorption (>3500%), and favorable sustained release properties, enabling effective cellular interactions. Notably, SSFx@TCP cryogels support cell attachment, proliferation, differentiation, while also regulate gene expression associated angiogenesis osteogenesis. Furthermore, vivo assays demonstrated that can effectively promote de novo production rat calvarial defect model 8 weeks post-operatively, indicating their potential mimic natural extracellular matrix. The successful integration bioactive components may be beneficial improved clinical outcomes therapies ultimately patient care reconstructive surgery.

Language: Английский

Citations

1
Biomimetic Structural Design in 3D-Printed Scaffolds for Bone Tissue Engineering DOI Creative Commons
Dan Huang, Zuhao Li, Guangfeng Li

et al.

Materials Today Bio, Journal Year: 2025, Volume and Issue: 32, P. 101664 - 101664

Published: March 14, 2025

Language: Английский

Citations

1
Applications and Progress of 3D Printed Bioceramic Scaffolds in Bone Tissue Repair and Immune Regulation DOI

Yasi Chen,

Shaohao Quan,

Sirui Huang

et al.

Ceramics International, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 1, 2024

Language: Английский

Citations

4
Bone augmentation of maxillary sinus floor elevation with hydroxyapatite/ poly(lactide-co-caprolactone) composites DOI Creative Commons

Zuohui Xiao,

Jingjing Deng, Ling Wei

et al.

Materials Today Nano, Journal Year: 2025, Volume and Issue: unknown, P. 100624 - 100624

Published: April 1, 2025

Language: Английский

Citations

0
Dual Nano-Reinforced 3D-Printed Polylactic Acid Scaffolds for Antibacterial and Osteogenic Applications DOI
Wang Guo,

Yuezhen Wei,

Bowen Li

et al.

ACS Applied Nano Materials, Journal Year: 2025, Volume and Issue: unknown

Published: May 8, 2025

Language: Английский

Citations

0
A comprehensive analysis of two types of xenogeneic bone particles for use in maxillofacial bone regeneration therapies DOI Creative Commons
Olimpia Ortiz‐Arrabal, Mario A. Rodríguez, Jesús Chato‐Astrain

et al.

PLoS ONE, Journal Year: 2025, Volume and Issue: 20(5), P. e0323754 - e0323754

Published: May 19, 2025

Regeneration of maxillofacial bone structures is challenging. One strategy for damage repair involves using filler particles. This study analyzed the regenerative potential deproteinized particles (DP) and collagen-based (CP) to determine effectiveness each biomaterial in repair. Structural analysis scanning electron microscopy 3D showed that DP CP were structurally similar, comprising a heterogeneous mixture varying sizes shapes. Ex vivo analyses, including morphological evaluation, LIVE & DEAD assays, DNA quantification, demonstrated high biocompatibility with human cells both direct indirect contact at 24, 48, 72 hours. Both grafted onto Wistar rats critical mandibular defect two months. Computed tomography revealed significant reduction group, but not compared negative controls without any Histological identified tissue collagen fibers mineralized spots DP, more DP. Histochemistry immunohistochemistry confirmed collagen, proteoglycans, osteocalcin presence regeneration area These results confirm particle types regeneration, particularly CP. Future studies should assess their clinical usefulness patients cleft palate, damage, other applications involving engineering techniques.

Language: Английский

Citations

0
A Sr@Ag-based spatiotemporal and step-release scaffold against chronic osteomyelitis, fabricated by coaxial 3D-printing DOI
Jingyun Wang, Qin Zhang,

Hetong Wang

et al.

Biomaterials, Journal Year: 2024, Volume and Issue: 314, P. 122899 - 122899

Published: Oct. 18, 2024

Language: Английский

Citations

3
Nanosheet-assembled porous-wall hollow hydroxyapatite microspheres prepared by a template-free hydrothermal method for pH-responsive drug release DOI

Wei‐li Xu,

Yu‐peng Lu,

Gui‐yong Xiao

et al.

Ceramics International, Journal Year: 2024, Volume and Issue: 50(22), P. 47501 - 47506

Published: Sept. 3, 2024

Language: Английский

Citations

1