Engineered Conductive Metal–organic Frameworks for Electrochemical Detection of Urinary Biomarkers

Small, Journal Year: 2024, Volume and Issue: unknown

Published: Nov. 22, 2024

Abstract The increasing prevalence of health concerns has sparked a demand for advanced monitoring tools, which is significant challenge researchers. Analysis biofluid samples and biomarker vital comprehensive assessment. In this context, metal–organic frameworks (MOFs) have emerged as one the leading materials developing cutting‐edge artificial sensors. These unique MOFs been developed from metallic organic linkers consist tunable pores dynamic surface areas, attracting various guest molecules to participate in electrochemical devices. This study gateway world where MOF designs transcend mere inventions, morphing into electric marvels that revolutionize urine sample monitoring. From inception design fabrication sensors tailored applications, prides itself on elucidating factors affecting MOF‐based electrical devices Moreover, focus placed conductivity, electrode properties, recent state‐of‐the‐art analysis, highlighting pivotal role biomarkers play honing resilience performance Finally, specific used analysis. It will attract researchers develop new portable tools by analyzing samples.

Language: Английский

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Copper Recovery from Mobile Phone Printed Circuit Board E-Waste and Transforming into CuO@C for Electrode Material in Extended Gate Field-Effect Transistors Facilitating Non-Enzymatic Ascorbic Acid Detection

ACS Sustainable Chemistry & Engineering, Journal Year: 2024, Volume and Issue: 12(29), P. 10752 - 10764

Published: July 8, 2024

This study presents a new approach for the simultaneous leaching and sorption of Cu(II) from waste printed circuit board (PCB) flakes using phosphorylated cellulose (P(O)-cellulose). The leaching-sorption experiments were conducted at various temperatures (25, 45, 60 °C) pH values (4, 7, 10). Phosphorylated successfully facilitated recovery under optimal conditions identified 7 °C, achieving efficiency 35.9 mg/g. Further, recovered Cu(II)-P(O)-cellulose was treated with glycine to form copper-glycinate quantification. then used synthesize Cu/CuO CuO nanoparticles supported on carbon (Cu/CuO@C CuO@C) through calcination 400 700 respectively. synthesized CuO@C material exhibited remarkable performance as an electrode ascorbic acid biosensing via EGFET configuration. dynamic demonstrated its superior response in concentration range 20–2300 μM, time less than 6 s 1× PBS, which mimics physiological condition body fluids. displayed high sensitivity (821.94 μA·dec–1·cm–2) low detection limit 0.047 showcasing potential sensitive selective detection. Utilizing sustainable functionalized derivative, copper extracted e-waste PCBs repurposed applications.

Language: Английский

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Transparent TiO₂/MoO₃ Heterojunction-Based Photovoltaic Self-Powered Triethylamine Gas Sensor with IoT-Enabled Smartphone Interface

ACS Sensors, Journal Year: 2024, Volume and Issue: 9(12), P. 6592 - 6604

Published: Nov. 26, 2024

Conventional gas sensors encounter a significant obstacle in terms of power consumption, making them unsuitable for integration with the next generation smartphones, wireless platforms, and Internet Things (IoT). Energy-efficient sensors, particularly self-powered can effectively tackle this problem. The researchers are strides advancing photovoltaic by employing diverse materials their compositions. Unfortunately, several these seem complex fabrication mainly target oxidizing species detection. To address issues, we have successfully employed transparent, cost-efficient solution processed bilayer TiO2/MoO3 heterojunction-based sensor superior VOC sensing capabilities, marking milestone field. scanning Kelvin probe (SKP) measurement reveals remarkable change contact potential difference (−23 mV/kPa) bilayered film after UV light exposure triethylamine (TEA) atmosphere, indicating highest reactivity between TEA molecules TiO2/MoO3. Under mode, further demonstrates exceptional sensitivity (∼2.35 × 10–3 ppm–1) to compared other studied VOCs, an admirable limit detection (22 ppm) signal-to-noise ratio (1540). Additionally, shows ability recognize estimate its composition binary mixture VOCs from similar class. strongest affinity toward molecule, lowest covalent bond energy, electron-donating nature may be attributed adsorption TEA. We demonstrate practical applicability prototype device connected smartphone via IoT, enabling continuous surveillance

Language: Английский

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Influence of gas adsorption on surface potential of porphyrin functionalized boron doped diamond thin films

Surfaces and Interfaces, Journal Year: 2024, Volume and Issue: 50, P. 104456 - 104456

Published: May 8, 2024

Language: Английский

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Tuning Mn-MOF by Incorporating a Phthalocyanine Derivative as an Enzyme Mimic for Efficient EGFET-based Ascorbic Acid Detection

ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown

Published: March 28, 2025

In this study, we present the effect of catalytic performance in Mn-MOF upon incorporating varied concentrations phthalocyanine derivative (H2PcP8OH16) for ascorbic acid detection an extended gate field-effect transistor (EGFET) configuration. The fabricated Mn-OM-MOF-2/CP electrode demonstrated notable selectivity toward physiological conditions sweat, with a sensitivity 71.375 μA·mM–1·cm–2, response time less than 6 s, and linear range from 5 to 240 μM. limit (LOD) quantification (LOQ) were found be 0.26 0.78 μM, respectively. Remarkably, prepared electrodes followed Michaelis–Menten kinetics. Among them, highest affinity acid, Km value 0.142 mM. To gain deeper insights into charge transfer mechanism during interaction Mn-OM-MOF-2/CP, employed scanning Kelvin probe (SKP) technique conducted post-FTIR analysis understand sensing mechanism. Additionally, post-UV–visible (UV–vis) measurements performed explore how incorporation enhances affinity. Additional studies using standard artificial sweat have confirmed electrode's good recovery. Overall, results EGFET method suitability rapid, noninvasive, single-use 1× phosphate buffer saline (1× PBS).

Language: Английский

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Combinatorial Scanning Kelvin Probe and Density Functional Theory Studies on Selective n-Butanol Adsorption Properties of pH-Dependent Bi₂WO₆ Nanostructures

ACS Applied Electronic Materials, Journal Year: 2024, Volume and Issue: unknown

Published: Aug. 8, 2024

Fast and effective detection of volatile organic compounds (VOCs) is a crucial criterion for developing stable room-temperature operable gas sensors. In this work, we have synthesized Bi2WO6 (BW) nanostructures using the hydrothermal method at pH 1 (BW-1), pH-3 (BW-3), 5 (BW-5), 7 (BW-7), 9 (BW-9) to study their VOC adsorption properties. X-ray diffraction confirms that both internal strain crystallite size increase with pH. Field-emission scanning electron microscope results showed change in morphology BW from flakes sheets. The obtained surface photovoltage, photoluminescence spectra, Raman photoelectron spectroscopy revealed defects oxygen vacancies Further, properties are examined Kelvin probe system through contact potential difference measurements dark visible light conditions air various VOCs like n-butanol, benzene, triethylamine, acetone. BW-9 sample has exhibited ∼40% enhanced photoresponse under an n-butanol atmosphere compared BW-1. chemiresistive sensing performance between 50 400 ppm exhibits sensitivity value 0.00816 ± 0.0007 ppm–1. Computational investigations density functional theory confirmed surface-adsorbed on shows higher affinity energy −0.877 eV among other VOCs. Overall, these combined experimental computational studies demonstrated selective behavior toward industrial pollutant.

Language: Английский

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EGFET-Based Noninvasive Glucose Sensor Integrated with Enzyme-Mimicking Bi₂O₃ Microrods Derived from Bi-BTC Tested in Artificial Sweat

ACS Applied Electronic Materials, Journal Year: 2024, Volume and Issue: unknown

Published: July 26, 2024

For diabetic patients, effective glucose monitoring is critical, which makes the development of inexpensive, enzyme-free, and nonintrusive sensors necessary. Conventional techniques have not been consistent, necessitating intricate instrumentation protocols that drive up prices, impede downsizing, take too long. The presented research attempts to develop a stable Bi2O3 (bismuth oxide)-sensing electrode derived from Bi-BTC [bismuth (Bi)─1,3,5-benzenetricarboxylic acid (BTC)]. This operates through an extended gate field-effect transistor configuration designed facilitate noninvasive monitoring. exhibits high sensitivity 351.68 μA mM–1 cm–2, limit detection 3.7 μM, quick response time less than 5 s in 1× phosphate-buffered saline, effectively covering linear range 20 1300 μM. Bi-BTC-derived Bi2O3-sensing follows Michaelis–Menten kinetics glucose, with Km value 0.86 mM, lower 0.89 mM for oxidase, implying has strong affinity toward glucose. Most remarkably, we used measurements scanning Kelvin probe show relationship between electrode's work function. Additional using standard artificial sweat demonstrated excellent recovery electrode. Overall, our findings shown how well prepared can quickly detect levels, providing encouraging opportunities diagnosis diabetes mellitus.

Language: Английский

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Brewer’s Spent Grain-Cellulose-Coated Copper Electrode-Based Extended Gate Field-Effect Transistor for Nonenzymatic Glucose Detection toward Diagnosis of Diabetes Mellitus

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: unknown

Published: Sept. 25, 2024

The demand for environmentally friendly, reliable, and cost-effective electrodes glucose sensor technology has become a major research area in the paradigm shift toward green electronics. In this regard, cellulose emerged as promising flexible biopolymer solution with unique properties such biocompatibility, biodegradability, nontoxicity, renewability, sustainability. Because of their large surface porous structure, fibrous substrates quickly adsorb disperse analytes at detection sites. This work focuses on utilizing glyoxal-treated (derived from brewer's spent grain (BSG)) fabrication extended gate field-effect transistor (EGFET)-based sensors. investigation extends to utilization BSG-cellulose biomimicking electrolytes (phosphate buffer saline) facilitate human blood samples. fabricated electrode demonstrates linear range 1 13.5 mM Langmuir adsorption coefficient (

Language: Английский

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Porphyrinoid-Functionalized ZnO Nanoflowers for Visible Light-Enhanced and Selective Benzylamine Detection at Room Temperature

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(44), P. 61204 - 61217

Published: Oct. 22, 2024

Functionalization of hybrid organic molecules as layers on ZnO nanoflowers (NFs) gives an excellent combination sensing toward visible light and vapors various volatile compounds (VOCs). In this work, functionalized NFs were utilized for the photoinduced detection benzylamine at room temperature. The synthesized via a facile solution route with four different porphyrin-conjugated namely (i) pyrene-porphyrin (PP), (ii) pyrene- porphyrinato zinc (ZnPP), (iii) triphenylamine- porphyrin (TP) (iv) (ZnTP). diameter flower-like structure was found to be ∼3.2 μm thickness petals being ∼24.1 nm. gas adsorption performance activation temperature studied by using scanning Kelvin probe (SKP) system. improved properties samples can attributed heterojunctions activation. particular, enhanced response ZnTP (ZnTPZ) observed. Further, static experiments ZnTPZ under concentrations (1, 3, 5, 10, 15, 25 ppm) both in dark conditions have exhibited linear increase response. selectively compared that pristine thus confirmed 1 ppm benzylamine. sensitivity limit sensor calculated 0.0292 ppm-1 197 ppb, respectively. coordination metal (Zn) has helped effective charge transfer between providing additional active sites interactions. Also, density functional theory calculations demonstrated role surface improving adsorption. fresh cabbage real sample analysis proposed illumination conditions, obtained low evaluation Overall, results suggest development novel ZnTPZ-based light-activated sensors These kinds used track freshness vegetables they are transported from farms commercial outlets.

Language: Английский

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A Step Towards Non-Invasive Diagnosis of Diabetes Mellitus Using In-Situ Synthesized MOF-MXene Hybrid Material with Extended Gate Field-Effect Transistor Integration

Journal of Materials Chemistry B, Journal Year: 2024, Volume and Issue: unknown

Published: Dec. 2, 2024

Integration of MOF-MXene hybrid material into an EGFET configuration for enzyme-free and non-invasive glucose detection to diagnose diabetes mellitus.

Language: Английский

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