3D Printing of High Strength Thermally Stable Sustainable Lightweight Corrosion-Resistant Nanocomposite by Solvent Exchange Postprocessing DOI
Sayan Ganguly, Xiaowu Tang

ACS Sustainable Chemistry & Engineering, Journal Year: 2024, Volume and Issue: 13(1), P. 423 - 435

Published: Dec. 18, 2024

3D printing of cellulose acetate (CA)-based, sustainable, thermally stable nanocomposites is challenging due to their fast drying, nozzle clogging, and complex rheological behavior. In this study, we developed an extrusion-printable ink based on CA nanocrystals (CNCs) using a trisolvent wet blending method, followed by postprinting pore-inducing processing technique. The performed well in both tensile- compression-based mechanical tests. Moreover, the demonstrated malleable deformation during compression testing without any premature fracture, unlike commercial commodity plastics. thermal stability was assessed thermogravimetric analysis, showing ∼ 28 °C improvement onset degradation temperature after addition 5 wt % CNCs. Solvent tolerance tests against various solvents indicated excellent solvent resistance. lightweight showed no deterioration, even long-term exposure water vapor. Finally, anticorrosion behavior samples evaluated as coating material for metal (Al), demonstrating protection corrosive acid vapors. Thus, application 3D-printed exhibits significant promise implementation fields lightweight, anticorrosive engineering materials.

Language: Английский

Magnetic Polymeric Conduits in Biomedical Applications DOI Creative Commons
Sayan Ganguly, Shlomo Margel

Micromachines, Journal Year: 2025, Volume and Issue: 16(2), P. 174 - 174

Published: Jan. 31, 2025

Magnetic polymeric conduits are developing as revolutionary materials in regenerative medicine, providing exceptional benefits directing tissue healing, improving targeted medication administration, and facilitating remote control via external magnetic fields. The present article offers a thorough examination of current progress the design, construction, functionalization these hybrid systems. integration nanoparticles into matrices confers distinctive features, including regulated alignment, improved cellular motility, medicinal delivery, while preserving structural integrity. Moreover, incorporation multifunctional attributes, such electrical conductivity for cerebral stimulation optical characteristics real-time imaging, expands their range applications. Essential studies indicate that dimensions, morphology, surface chemistry, composition significantly affect biocompatibility, degrading characteristics, overall efficacy. Notwithstanding considerable advancements, issues concerning long-term biodegradability, scalability persist, addition to must uniform regulatory frameworks facilitate clinical translation. Progress additive manufacturing nanotechnology is overcoming obstacles, creation dynamic adaptive conduit structures designed particular biomedical requirements. conduits, by integrating usefulness safety, set transform therapies, presenting new avenue customized medicine advanced healthcare solutions.

Language: Английский

Citations

2

Development of quercetin-loaded electrospun nanofibers through shellac coating on gelatin: Characterization, colon-targeted delivery, and anticancer activity DOI
Shu‐Fang Li, Teng‐Gen Hu, Hong Wu

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 277, P. 134204 - 134204

Published: July 26, 2024

Language: Английский

Citations

10

Injectable and 3D Extrusion Printable Hydrophilic Silicone-Based Hydrogels for Controlled Ocular Delivery of Ophthalmic Drugs DOI
Sayan Ganguly, David Wulff,

Chau-Minh Phan

et al.

ACS Applied Bio Materials, Journal Year: 2024, Volume and Issue: 7(9), P. 6286 - 6296

Published: Sept. 3, 2024

While silicone elastomers have found widespread use in the biomedical industry, 3D printing them has proven to be difficult due material's slow drying time, low viscosity, and hydrophobicity. Herein, we arrested hydrophilic (HS) macrochains into a semi-interpenetrating polymer network (semi-IPN) via an

Language: Английский

Citations

7

Recent advances on chitosan/hyaluronic acid-based stimuli-responsive hydrogels and composites for cancer treatment: A comprehensive review DOI

Fahad Alsaikhan,

Bagher Farhood

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: unknown, P. 135893 - 135893

Published: Sept. 1, 2024

Language: Английский

Citations

7

State-of-the-art progress on locust bean gum polysaccharide for sustainable food packaging and drug delivery applications: A review with prospectives DOI
Siva Sankar Sana, Chaitany Jayprakash Raorane, Raja Venkatesan

et al.

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 275, P. 133619 - 133619

Published: July 2, 2024

Language: Английский

Citations

6

Green micellar UPLC and complementary eco-friendly spectroscopic techniques for simultaneous analysis of anti-COVID drugs: a comprehensive evaluation of greenness, blueness, and whiteness DOI Creative Commons

Noha S. Katamesh,

Ahmed Emad F. Abbas, Michael K. Halim

et al.

BMC Chemistry, Journal Year: 2024, Volume and Issue: 18(1)

Published: Aug. 9, 2024

The development of sustainable analytical methodologies that minimize hazards, waste generation, and energy consumption has become crucial. This study introduces pioneering green‒blue-white approaches for the simultaneous quantification montelukast sodium (MLK) fexofenadine hydrochloride (FEX) in combination formulations. first approach employs an ultra-performance liquid chromatographic method (UPLC) with a green micellar mobile phase 0.02 M dodecyl sulfate 10% 1-pentanol (65:35%). demonstrated excellent resolution, peak symmetry, short analysis time, retention times 3.53 min MLK 1.67 FEX. FEX linearities were 1-260 1.2-312 μg/mL, respectively. second involves complementary built-in spectroscopic techniques (second derivative, third ratio difference methods) using water as solvent, providing green, simple, low-cost alternative laboratories where expensive devices may not be readily available. 3-50 3-60 All methods comprehensively validated showed satisfactory results. proposed linearity (r

Language: Английский

Citations

6

Stimuli‐Responsive Core‐Shell Electrospun Nanofibers for Drug Delivery: A Mini‐Review DOI Creative Commons

Songpei Xie,

Jing Zhang,

Chase Orf

et al.

Journal of Applied Polymer Science, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 31, 2025

ABSTRACT Core‐shell nanofibers have the potential to surpass traditional monolithic electrospun in drug delivery, due their ability encapsulate sensitive therapeutics within core, protect them from degradation, and enable controlled release profiles through shell. When designed be stimuli‐responsive, these evolve “smart” delivery platforms for advanced therapeutic applications. This mini‐review examines recent advancements fabrication applications of stimuli‐responsive core‐shell nanofibers. Key techniques, such as coaxial electrospinning, single‐nozzle electrospinning using water‐in‐oil or oil‐in‐water emulsions immiscible blends (e.g., polyethylene oxide chitosan; polyvinylpyrrolidone polyvinylidene), needleless post‐fabrication coating methods, are discussed along with respective advantages limitations. Additionally, review also explores how can engineered respond stimuli like near‐infrared (NIR) light, ultrasound, temperature, pH changes. Representative examples illustrate reduce initial burst release, on‐demand chemodrug implement photothermal therapy against cancer cells. At end, we offer perspectives on challenges, opportunities, new directions future development.

Language: Английский

Citations

0

Magnetic Ionogel and Its Applications DOI Creative Commons
Sayan Ganguly, Shlomo Margel

Gels, Journal Year: 2025, Volume and Issue: 11(4), P. 219 - 219

Published: March 21, 2025

Magnetic ionogels, a category of hybrid materials consisting magnetic nanoparticles and ionic liquids, have garnered significant interest owing to their remarkable attributes, including tunability, flexibility, reactivity external fields. These provide distinctive amalgamation the benefits both resulting in improved efficacy across many applications. ionogels may be readily controlled using fields, rendering them suitable for drug administration, biosensing, soft robotics, actuators. The capacity incorporate these into dynamic systems presents novel opportunities development responsive, intelligent capable real-time environmental adaptation. Nonetheless, despite promising potential problems persist, optimization particle dispersion, enhancement ionogel mechanical strength, improvement long-term stability. This review comprehensive examination syntheses, characteristics, uses emphasizing breakthroughs persistent within domain. We examine recent advancements prospective research trajectories aimed at enhancing design practical applications diverse biomedical uses, sensors, next-generation seeks elucidate present status influence on science engineering.

Language: Английский

Citations

0

Chemical interactive behaviors of drugs DOI

Kavita Ravindra Chandramore,

Shirish Sangle,

Poonam Patil

et al.

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 41 - 62

Published: Jan. 1, 2025

Language: Английский

Citations

0

Commercially adoptable nanotechnology platform for illicit drug sensing DOI
Sayan Ganguly

Elsevier eBooks, Journal Year: 2025, Volume and Issue: unknown, P. 323 - 349

Published: Jan. 1, 2025

Language: Английский

Citations

0