Bioactive Materials,
Journal Year:
2024,
Volume and Issue:
37, P. 30 - 50
Published: March 14, 2024
As
an
endogenous
signaling
molecule,
carbon
monoxide
(CO)
has
emerged
as
increasingly
promising
option
regarding
gas
therapy
due
to
its
positive
pharmacological
effects
in
various
diseases.
Owing
the
gaseous
nature
and
potential
toxicity,
it
is
particularly
important
modulate
CO
release
dosages
targeted
locations
elucidate
biological
mechanisms
of
facilitate
clinical
applications.
Based
on
these,
diverse
CO-releasing
molecules
(CORMs)
have
been
developed
for
controlled
systems.
However,
practical
applications
these
CORMs
are
limited
by
several
disadvantages
including
low
stability,
poor
solubility,
weak
releasing
controllability,
random
diffusion,
toxicity.
In
light
rapid
developments
advantages
nanomedicine,
abundant
nanomaterials
ways
therapeutic
purposes
across
Due
their
nanoscale
sizes,
diversified
compositions
modified
surfaces,
vast
(CORNMs)
constructed
exhibited
specific
under
stimuli
with
better
pharmacokinetics
pharmacodynamics.
this
review,
we
present
recent
progress
CORNMs
according
compositions.
Following
a
concise
introduction
therapy,
CORNMs,
representative
research
from
organic
nanostructures,
hybrid
nanomaterials,
inorganic
nanocomposites
elaborated.
The
basic
properties
such
active
components,
mechanisms,
detection
methods,
applications,
discussed
detail
listed
table.
Finally,
explore
discuss
prospects
challenges
associated
utilizing
release.
Advanced Functional Materials,
Journal Year:
2023,
Volume and Issue:
33(40)
Published: June 3, 2023
Abstract
The
past
few
decades
have
witnessed
the
flourish
of
creating
metal
oxides
for
biocatalytic
therapeutics
due
to
their
structural
diversities,
feasible
modifications,
tunable
catalytic
sites,
and
low
cost
when
compared
natural
enzyme
counterparts.
Here,
in
this
timely
review,
most
recent
progress
future
trends
engineering
structured
decoding
structure‐reactivity
relationships
is
comprehensively
summarized.
At
first,
fundamental
activities,
evaluations,
mechanisms
oxide‐based
biocatalysts
are
carefully
disclosed.
Subsequently,
merits,
design
methods,
state‐of‐art
achievements
different
types
nanostructured
biofunctionalized
thoroughly
discussed.
Thereafter,
it
provides
detailed
comments
on
center
modulation
strategies
engineer
efficient
reactive
oxygen
species
(ROS)‐catalysis,
including
atomic
site
engineering,
heterostructures,
support
effects.
Furthermore,
representative
applications
these
ROS‐catalytic
been
systematically
summarized,
such
as
disinfections,
cancer
therapies,
ROS
scavenging
anti‐inflammations,
sensors,
well
corresponding
toxicities.
Finally,
current
challenges
perspectives
also
highlighted.
It
believed
that
review
can
provide
cutting‐edge
multidisciplinary
instruction
stimulate
widespread
utilization
broad
therapeutic
applications.
Angewandte Chemie International Edition,
Journal Year:
2024,
Volume and Issue:
63(16)
Published: March 2, 2024
Hybrid
nanomaterials
have
found
use
in
many
biomedical
applications.
This
article
provides
a
comprehensive
review
of
the
principles,
techniques,
and
recent
advancements
design
fabrication
hybrid
for
biomedicine.
We
begin
with
an
introduction
to
general
concept
material
hybridization,
followed
by
discussion
how
this
approach
leads
materials
additional
functionality
enhanced
performance.
then
highlight
forms
nanostructures,
nanocomposites,
metal-organic
frameworks,
biohybrids,
including
their
methods.
also
showcase
advance
engineering
context
nanomedicine,
regenerative
medicine,
diagnostics,
theranostics,
biomanufacturing.
Finally,
we
offer
perspectives
on
challenges
opportunities.
Angewandte Chemie,
Journal Year:
2024,
Volume and Issue:
136(16)
Published: March 2, 2024
Abstract
Hybrid
nanomaterials
have
found
use
in
many
biomedical
applications.
This
article
provides
a
comprehensive
review
of
the
principles,
techniques,
and
recent
advancements
design
fabrication
hybrid
for
biomedicine.
We
begin
with
an
introduction
to
general
concept
material
hybridization,
followed
by
discussion
how
this
approach
leads
materials
additional
functionality
enhanced
performance.
then
highlight
forms
nanostructures,
nanocomposites,
metal–organic
frameworks,
biohybrids,
including
their
methods.
also
showcase
advance
engineering
context
nanomedicine,
regenerative
medicine,
diagnostics,
theranostics,
biomanufacturing.
Finally,
we
offer
perspectives
on
challenges
opportunities.
Bioactive Materials,
Journal Year:
2024,
Volume and Issue:
37, P. 30 - 50
Published: March 14, 2024
As
an
endogenous
signaling
molecule,
carbon
monoxide
(CO)
has
emerged
as
increasingly
promising
option
regarding
gas
therapy
due
to
its
positive
pharmacological
effects
in
various
diseases.
Owing
the
gaseous
nature
and
potential
toxicity,
it
is
particularly
important
modulate
CO
release
dosages
targeted
locations
elucidate
biological
mechanisms
of
facilitate
clinical
applications.
Based
on
these,
diverse
CO-releasing
molecules
(CORMs)
have
been
developed
for
controlled
systems.
However,
practical
applications
these
CORMs
are
limited
by
several
disadvantages
including
low
stability,
poor
solubility,
weak
releasing
controllability,
random
diffusion,
toxicity.
In
light
rapid
developments
advantages
nanomedicine,
abundant
nanomaterials
ways
therapeutic
purposes
across
Due
their
nanoscale
sizes,
diversified
compositions
modified
surfaces,
vast
(CORNMs)
constructed
exhibited
specific
under
stimuli
with
better
pharmacokinetics
pharmacodynamics.
this
review,
we
present
recent
progress
CORNMs
according
compositions.
Following
a
concise
introduction
therapy,
CORNMs,
representative
research
from
organic
nanostructures,
hybrid
nanomaterials,
inorganic
nanocomposites
elaborated.
The
basic
properties
such
active
components,
mechanisms,
detection
methods,
applications,
discussed
detail
listed
table.
Finally,
explore
discuss
prospects
challenges
associated
utilizing
release.
