Biochemical Pharmacology, Journal Year: 2024, Volume and Issue: 229, P. 116523 - 116523
Published: Sept. 7, 2024
Language: Английский
Nano Today, Journal Year: 2024, Volume and Issue: 55, P. 102212 - 102212
Published: Feb. 26, 2024
Language: Английский
Citations
19
ACS Nano, Journal Year: 2024, Volume and Issue: 18(20), P. 13171 - 13183
Published: May 8, 2024
The forefront of micro- and nanorobot research involves the development smart swimming micromachines emulating complexity natural systems, such as swarming collective behaviors typically observed in animals microorganisms, for efficient task execution. This study introduces magnetically controlled microrobots that possess polymeric sequestrant "hands" decorating a magnetic core. Under influence external fields, functionalized beads dynamically self-assemble from individual microparticles into well-defined rotating planes diverse dimensions, allowing modulation their propulsion speed, exhibiting motion. These mobile microrobotic swarms can actively capture free-swimming bacteria dispersed microplastics "on-the-fly", thereby cleaning aquatic environments. Unlike conventional methods, these be collected complex media release captured contaminants second vessel controllable manner, is, using ultrasound, offering sustainable solution repeated use decontamination processes. Additionally, residual water is subjected to UV irradiation eliminate any remaining bacteria, providing comprehensive solution. In summary, this shows microrobot design
Language: Английский
Citations
19
Light Science & Applications, Journal Year: 2025, Volume and Issue: 14(1)
Published: Jan. 8, 2025
Language: Английский
Citations
3
Research, Journal Year: 2025, Volume and Issue: 8
Published: Jan. 1, 2025
Nano-/microrobots have been demonstrated as an efficient solution for environmental remediation. Their strength lies in their propulsion abilities that allow active “on-the-fly” operation, such pollutant detection, capture, transport, degradation, and disruption. Another advantage is versatility, which allows the engineering of highly functional solutions a specific application. However, latter can bring complexity to applications; versatility dimensionality, morphology, materials, surface decorations, other modifications has crucial effect on resulting abilities, compatibility with environment, overall functionality. Synergy between decorations its projection functionality object nanoarchitectonics. Here, we scrutinize nano-/microrobots eyes nanoarchitectonics: list general concepts help assess synergy limitations individual procedures fabrication processes operation at macroscale. The nanoarchitectonics approached from microscopic level, focusing dimensionality through nanoscopic evaluating influence decoration nanoparticles quantum dots, moving molecular single-atomic level very fine tuning presented review aims lay provide overview advanced nano-/microrobot remediation beyond.
Language: Английский
Citations
2
The European Physical Journal E, Journal Year: 2025, Volume and Issue: 48(2)
Published: Feb. 1, 2025
In the past years, amount of research on active matter has grown extremely rapidly, a fact that is reflected in particular by existence more than 1000 reviews this topic. Moreover, field become very diverse, ranging from theoretical studies statistical mechanics particles to applied work medical applications microrobots and biological systems artificial swimmers. This makes it difficult get an overview over as whole. Here, we provide such form metareview article surveys existing review articles books matter. Thereby, provides useful starting point for finding literature about specific
Language: Английский
Citations
2
Journal of the American Chemical Society, Journal Year: 2023, Volume and Issue: 145(50), P. 27185 - 27197
Published: Dec. 8, 2023
Chemically powered nano- and micromotors are microscopic devices that convert chemical energy into motion. Interest in these motors has grown over the past 20 years because they exhibit interesting collective behaviors have found potential uses biomedical environmental applications. Understanding how operate both individually collectively environments affect their operation is of fundamental applied significance. However, there still significant gaps our knowledge. This Perspective highlights several open questions regarding propulsion mechanisms of, interactions among, impact confinements on driven by self-generated gradients. These based my own experience as an experimentalist. For each question, I describe problem its significance, analyze status-quo, identify bottleneck problem, propose solutions. An underlying theme for interplay among reaction kinetics, physicochemical distributions, fluid flows. Unraveling this requires careful measurements well a close collaboration between experimentalists theoreticians/numerical experts. The interdisciplinary nature challenges suggests solutions could bring new revelations opportunities across disciplines such colloidal sciences, material soft matter physics, robotics, beyond.
Language: Английский
Citations
28
Advanced Materials, Journal Year: 2024, Volume and Issue: unknown
Published: April 23, 2024
Swarm behaviors are common in nature, where individual organisms collaborate via perception, communication, and adaptation. Emulating these dynamics, large groups of active agents can self-organize through localized interactions, giving rise to complex swarm behaviors, which exhibit potential for applications across various domains. This review presents a comprehensive summary perspective synthetic swarms, bridge the gap between microscale swarms. It is begun by examining agents, fundamental units understand origins their motility functionality presence external stimuli. Then inter-agent communications agent-environment that contribute generation summarized. Furthermore, reported date emergence machine intelligence within reviewed. Eventually, enabled distinct swarms By discussing emergent insights offered into design deployment autonomous real-world applications.
Language: Английский
Citations
15
MRS Bulletin, Journal Year: 2024, Volume and Issue: 49(2), P. 115 - 124
Published: Feb. 1, 2024
Abstract The advent of small-scale robots holds immense potential for revolutionizing various industries, particularly in the domains surgery and operations within confined spaces that are currently inaccessible to conventional tools. However, their tethered nature dependence on external power sources impede progress. To surmount these challenges, integration batteries into diminutive emerges as a promising solution. This article explores robots, focusing “hard” “soft” approaches. challenges integrating rigid microrobots discussed. Various battery materials suitable microfabrication explored, along with creating three-dimensional structures optimize performance limited space. emphasizes need flexible deformable technologies seamlessly integrate soft robotic systems. Challenges related flexibility, stretchability, biocompatibility addressed. concept distributed mobile energy units, where smaller assemble larger bank, is proposed scalability adaptability. Extracting from environment, inspired by fuel cells, reduces reliance traditional batteries. offers valuable insights propelling advancements autonomous versatile By overcoming current limitations, integrated will unlock full across industries. Graphical abstract
Language: Английский
Citations
9
The Innovation, Journal Year: 2025, Volume and Issue: 6(2), P. 100777 - 100777
Published: Jan. 18, 2025
We developed magnetically driven bionic drug-loaded nanorobots (MDNs) to accurately target tumors and deliver chemotherapy agents using a customized three-dimensional (3D) magnetic manipulation platform (MMP) system precisely control their movement mode. MDNs were based on polyethylene glycol-modified homogeneous ultrasmall iron oxide nanoparticles (7.02 ± 0.18 nm). Doxorubicin (12% 2% [w/w]) was encapsulated in by an imide bond. could imitate the mode of school wild herrings (e.g., re-dispersion/arrangement/vortex/directional movement) adapt changing complex physiological environment through 3D MMP system. overcame blood flow resistance biological barriers optimized driving properties according vivo imaging (magnetic resonance fluorescence) histopathology. The performance fabricated verified cells tumor-bearing mouse models. showed high efficiency drug delivery targeting at tumor site (>10-fold), lower toxicity than free doxorubicin (5 mg/kg body weight), activated immune response site, significantly lengthened survival for mice. synergistic interaction between underscores immense potential this system, indicating revolution field chemotherapy.
Language: Английский
Citations
1
Angewandte Chemie International Edition, Journal Year: 2023, Volume and Issue: 63(9)
Published: Dec. 8, 2023
Self-assembly fundamentally implies the organization of small sub-units into large structures or patterns without intervention specific local interactions. This process is commonly observed in nature, occurring at various scales ranging from atomic/molecular assembly to formation complex biological structures. Colloidal particles may serve as micrometer-scale surrogates for studying assembly, particularly poorly understood kinetic and dynamic processes atomic scale. Recent advances colloidal self-assembly have enabled programmable creation novel materials with tailored properties. We here provide an overview comparison both passive active self-assembly, a discussion on energy landscape interactions governing types. In realm many impressive important been realized, including molecules, one-dimensional chains, two-dimensional lattices, three-dimensional crystals. contrast, driven by optical, electric, chemical, other fields, involves more intricate processes, offering flexibility potential new applications. A comparative analysis underscores critical distinctions between assemblies, highlighting unique collective behaviors emerging systems. These encompass motion, motility-induced phase segregation, exotic properties arising out-of-equilibrium thermodynamics. Through this comparison, we aim identify future opportunities research, which suggest application domains.
Language: Английский
Citations
20