Bimetallic Single-Atom Nanozyme-Based Electrochemical-Photothermal Dual-Function Portable Immunoassay with Smartphone Imaging

Analytical Chemistry, Journal Year: 2024, Volume and Issue: 96(33), P. 13663 - 13671

Published: Aug. 10, 2024

Rapid and accurate detection of human epidermal growth factor receptor 2 (HER2) is crucial for the early diagnosis prognosis breast cancer. In this study, we reported an iron-manganese ion N-doped carbon single-atom catalyst (FeMn-NC

Language: Английский

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On the Specificity of Nanozymes: A Perspective

Chinese Journal of Chemistry, Journal Year: 2024, Volume and Issue: 42(13), P. 1515 - 1522

Published: March 9, 2024

Comprehensive Summary We have compiled eight promising strategies for enhancing the specificity and selectivity of nanozymes, as depicted in comprehensive summary above. Enzymes exhibit intricate sophisticated structures, including substrate channels active sites, which can inform design nanozymes. Replication these structural features application facet engineering/doping techniques significantly enhance catalytic Alternatively, use Molecularly Imprinted Polymers (MIPs) to coat nanozymes represents an effective approach impart specificity. Furthermore, several straightforward stopgap been devised improve nanozyme analytical applications, such integration biorecognition elements sensor arrays through surface modification. image Key Scientists

Language: Английский

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Biomedical potential of nanozymes: Harnessing redox enzyme mimicry for theranostic applications

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 517, P. 215937 - 215937

Published: June 15, 2024

Language: Английский

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Oxidase mimicking nanozyme: Classification, catalytic mechanisms and sensing applications

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 520, P. 216166 - 216166

Published: Aug. 22, 2024

Language: Английский

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Mannose-Modified Multifunctional Iron-Based Nanozyme for Hepatocellular Carcinoma Treatment by Remodeling the Tumor Microenvironment

Colloids and Surfaces B Biointerfaces, Journal Year: 2025, Volume and Issue: 250, P. 114548 - 114548

Published: Feb. 3, 2025

Language: Английский

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Nanozyme-Based Cancer Nanotheranostics: Emerging Applications and Challenges in Brain Cancer Therapeutics

Journal of Nanotheranostics, Journal Year: 2025, Volume and Issue: 6(1), P. 4 - 4

Published: Jan. 31, 2025

Regrettably, despite undeniable advances in cancer diagnosis and therapy, primary brain (or cancer) remains one of the deadliest forms malignant tumors, where glioblastoma (GBM) is known as most diffuse glioma astrocytic lineage. Fortunately, to improve this scenario, remarkable progress nanotechnology has brought new promise raised expectations treatment. Nanomedicine, principally an area amalgamating with biology medicine, demonstrated a pivotal role, starting earliest detection while also offering novel multimodal therapy alternatives. In vast realm nanotechnology, nanozymes, type nanomaterial intrinsic enzyme-like activities characteristics connecting fields nanocatalysts, enzymology, biology, have emerged powerful nanotools for theranostics. Hence, fascinating field research experienced exponential growth recent years. As it virtually impossible cover all literature on broad domain science paper, review focuses presenting multidisciplinary approach, its content extending from fundamental knowledge nanozymes enzyme-mimicking catalysis targeting cancers. Although we are at very early stages research, can be envisioned that strategic development theranostics will positively offer disruptive nanoplatforms future nano-oncology.

Language: Английский

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Peptide nanozymes: An emerging direction for functional enzyme mimics

Bioactive Materials, Journal Year: 2024, Volume and Issue: 42, P. 284 - 298

Published: Sept. 4, 2024

Language: Английский

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Nanomaterials for co‐immobilization of multiple enzymes

BMEMat, Journal Year: 2024, Volume and Issue: unknown

Published: March 12, 2024

Abstract In order to co‐immobilize multiple enzymes, a wide range of nanomaterials has been designed achieve synergistic enzyme activity and enhance catalytic efficiency. Nanomaterials, as carriers for co‐immobilization, possess various advantages such tunable morphology size, high specific surface area, abundant chemically active sites. They can significantly stability, activity, We overview the commonly used methods strategies co‐immobilization. This review further summarizes latest research advances in co‐immobilization applications over past 5 years. Meanwhile, challenges these well some potential future directions are also discussed.

Language: Английский

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Doughnut-shaped bimetallic Cu–Zn-MOF with peroxidase-like activity for colorimetric detection of glucose and antibacterial applications

Talanta, Journal Year: 2024, Volume and Issue: 279, P. 126544 - 126544

Published: July 14, 2024

Language: Английский

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3D Film-Like Nanozyme with a Synergistic Amplification Effect for the Ultrasensitive Immunochromatographic Detection of Respiratory Viruses

ACS Nano, Journal Year: 2024, Volume and Issue: 18(37), P. 25865 - 25879

Published: Sept. 2, 2024

Greatly improving the sensitivity and detection range of lateral flow immunoassays (LFAs) by at least 100 times without using additional instruments remains challenging. Herein, we develop a three-dimensional (3D) film-like nanozyme (GO-Pt

Language: Английский

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