Process Biochemistry, Journal Year: 2024, Volume and Issue: 149, P. 158 - 168
Published: Dec. 12, 2024
Language: Английский
ACS Applied Materials & Interfaces, Journal Year: 2025, Volume and Issue: unknown
Published: Feb. 26, 2025
Periodontitis, a chronic inflammatory oral disease resulting from plaque biofilms, affects about 743 million individuals worldwide. However, the efficacy of current treatments is hampered by challenges in delivering antibiotics to recalcitrant biofilms and bacterial resistance, thereby impeding successful treatment infectious diseases. To address issues, an antibacterial photothermal material was designed, comprising spherical structure zinc oxide (ZnO) wrapped with triiron tetraoxide (Fe3O4). The outer layer adsorbed epsilon-polylysine (EPL) electrostatic action, ultimately leading fabrication Fe3O4/ZnO/EPL nanoparticles (FZE NPs). Fe3O4 core endowed efficient properties, facilitating dispersion dense which dramatically promoted adsorption penetration ZnO EPL into effectively kill bacteria vitro enhanced sterilization ability. Additionally, upon dissolution aqueous media, acts as positively charged antimicrobial peptide that adsorbs onto surface negatively membranes, modulating responses. In order ascertain FZE NPs, investigation conducted their effects against periodontitis-associated pathogen Porphyromonas gingivalis (P. gingivalis) vitro. Furthermore, antiperiodontitis potential NPs evaluated Sprague-Dawley (SD) rats ligamentous periodontitis. addition, toxicity evaluations indicated had acceptable biosafety profile vivo. summary, nanospheres NPs) represent promising therapeutic strategy for
Language: Английский
Citations
1
Molecules, Journal Year: 2025, Volume and Issue: 30(9), P. 2035 - 2035
Published: May 2, 2025
Mesoporous silica containing Au nanoclusters has been widely used in various fields owing to its desirable properties and functionality. This work introduces a facile method control the size of within hosts. was achieved by applying reducing gas at controlled temperature obtain narrow or broad cluster distribution inside host. The their hosts were characterized through X-ray diffraction, high-resolution transmission electron microscopy, energy-dispersive spectroscopy, ultraviolet-visible N2 sorption analysis, photoelectron spectroscopy. average 1.3 nm narrow-distribution sample. In comparison, wide-distribution sample exhibited two populations: 1–2 pores 5–30 outside pores. Methylene blue (M.B.) photocatalysis conducted under direct sunlight evaluate catalytic activity these materials. Sample 1–Au–SBA-11, clusters averaging nm, substantial M.B. degradation 90 min—half time required 2–Au–SBA-11 Such different ranges have potential applications across diverse fields.
Language: Английский
Citations
0
Journal of Nanobiotechnology, Journal Year: 2025, Volume and Issue: 23(1)
Published: March 6, 2025
Microbial keratitis, a sight-threatening corneal infection, remains significant global health concern. Conventional therapies using antimicrobial agents often suffers from limitations such as poor drug penetration, side effects, and occurrence of resistance, with prognosis. Novel treatment techniques, their unique properties targeted delivery capabilities, offers promising solution to overcome these challenges. This review delves into timely update the state-of-the-art advance therapeutics for keratitis treatment. The diverse microbial origins including viral, bacterial, fungal infections, exploring complex pathogenic mechanisms, followed by resistance mechanisms in pathogens are reviewed briefly. Importantly, emerging therapeutic techniques piezodynamic therapy, photothermal photodynamic nanoenzyme metal ion therapy summarized this showcasing potential traditional treatments. challenges future directions nanotechnology-based approaches discussed, focusing on safety, targeting strategies, combination therapies. aims inspire researchers revolutionize accelerate development functional materials different
Language: Английский
Citations
0
Applied Materials Today, Journal Year: 2025, Volume and Issue: 44, P. 102697 - 102697
Published: March 30, 2025
Language: Английский
Citations
0
International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(16), P. 8975 - 8975
Published: Aug. 18, 2024
Bacterial infection is one of the most problematic issues for human health and resistance bacteria to traditional antibiotics a matter huge concern. Therefore, research focusing on development new strategies efficiently kill these microorganisms. Recently, melanin starting be investigated this purpose. Indeed, very versatile material presents outstanding photothermal properties, already studied therapy, which can useful light-induced eradication bacteria. In review, we present antibacterial applications based effect, both single action its combination with other systems. Melanin, also thanks biocompatibility ease functionalization, has been demonstrated easily applicable as an antimicrobial agent, especially treatment local infections.
Language: Английский
Citations
3
Journal of Controlled Release, Journal Year: 2024, Volume and Issue: 377, P. 495 - 523
Published: Nov. 29, 2024
Language: Английский
Citations
1
ACS Omega, Journal Year: 2024, Volume and Issue: 9(47), P. 47122 - 47134
Published: Nov. 11, 2024
A Cu-TiO
Language: Английский
Citations
0
Process Biochemistry, Journal Year: 2024, Volume and Issue: 149, P. 158 - 168
Published: Dec. 12, 2024
Language: Английский
Citations
0