CrystEngComm, Journal Year: 2020, Volume and Issue: 22(43), P. 7341 - 7349
Published: Jan. 1, 2020
CSD data mining and energy calculations show that coformer self-interactions might significantly contribute to the packing stabilization of cocrystals.
Language: Английский
Nature Communications, Journal Year: 2021, Volume and Issue: 12(1)
Published: Oct. 21, 2021
Time resolved in situ (TRIS) monitoring has revolutionised the study of mechanochemical transformations but been limited by available data quality. Here we report how a combination miniaturised grinding jars together with innovations X-ray powder diffraction collection and state-of-the-art analysis strategies transform power TRIS synchrotron experiments. Accurate phase compositions, comparable to those obtained ex measurements, can be small sample loadings. Moreover, microstructural parameters (crystal size microstrain) also determined high confidence. This strategy applies all chemistries, is readily implemented, yields high-quality even using low energy source. offers direct avenue towards investigation reactions comprising scarce, expensive, or toxic compounds. Our applied model systems, including inorganic, metal-organic, organic mechanosyntheses, resolves previously misinterpreted mechanisms syntheses, promises broad, new directions for research.
Language: Английский
Citations
74
Crystal Growth & Design, Journal Year: 2023, Volume and Issue: 23(6), P. 4680 - 4700
Published: May 12, 2023
Cocrystal engineering is gaining interest across various disciplines since it can effectively tune the properties of solid substances via noncovalent synthesis by introducing new components into lattice. Mechanochemistry without a doubt most valuable tool for research cocrystals, which combines pursuit efficient and sustainable process pathways with exploration supramolecular synthons that cannot be discovered using solution methods. In this review, concerning significance mechanochemical we begin outlining strategies preparation cocrystals. We then elaborate on theoretical mechanisms mechanochemically induced formation cocrystals their polymorphs. On foundation, several cross-fields in mechanochemistry enhances application value cocrystal are shown to overcome existing limitations, difficult or impossible access conventional More importantly, demonstrate introduction methods, such as cultivating single crystals from melt microdroplets, techniques, microelectron diffraction (Micro-ED), has harmoniously united fields mechanochemistry. Finally, brief conclusion outlook presented, including current challenges future opportunities cooperation engineering.
Language: Английский
Citations
34
Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 517, P. 216035 - 216035
Published: June 25, 2024
Language: Английский
Citations
10
Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 159859 - 159859
Published: Jan. 1, 2025
Language: Английский
Citations
1
Crystals, Journal Year: 2021, Volume and Issue: 11(3), P. 303 - 303
Published: March 18, 2021
With an increasing interest in cocrystals due to various advantages, demand for large-scale cocrystallization techniques is rising. Solution a solvent-based approach that utilizes several single-component crystallization concepts as well equipment generating cocrystals. Solution-based can produce with reasonable control on purity, size distribution, morphology, and polymorphic form. Many of them also offer scalable solution the industrial production However, complexity thermodynamic landscape kinetics offers fresh challenges which are not encountered single component crystallization. This review focuses recent developments different pharmaceutically relevant The consists two sections. first section describes methods, highlighting their benefits limitations. second emphasizes developing these scale identifies major thrust areas where further research required.
Language: Английский
Citations
55
Chemical Communications, Journal Year: 2023, Volume and Issue: 59(95), P. 14052 - 14062
Published: Jan. 1, 2023
Twenty years ago, I wrote a Chem. Commun. feature article entitled “ Crystal Engineering: where from? Where to? ”: an update is in order.
Language: Английский
Citations
23
Journal of Agricultural and Food Chemistry, Journal Year: 2023, Volume and Issue: 71(28), P. 10500 - 10524
Published: July 7, 2023
Achieving rapid global agricultural development while maintaining ecological harmony is a major challenge of the new millennium. Meeting this requires efficient and environmentally friendly agrochemicals, including pesticides fertilizers. Molecular assembly, as promising strategy, has garnered significant attention in recent years for advanced solid-state forms agrochemicals. In review, we present potential advancements forms, such polymorphs, cocrystals/salts, solvates, inclusion compounds, amorphous state, production high-efficiency low-polluting agrochemical products. We provide an overview concepts preparation methods these followed by exploration their applications sustainable agriculture. Specifically, highlight value enhancing pesticide solubility, enabling controlled release chemical fertilizers, reducing off-target risks. Lastly, discuss challenges prospects associated with utilization advancement
Language: Английский
Citations
22
World Journal of Microbiology and Biotechnology, Journal Year: 2024, Volume and Issue: 40(3)
Published: Jan. 28, 2024
Abstract Pseudomonas fluorescens complex consists of environmental and some human opportunistic pathogenic bacteria. It includes mainly beneficial few phytopathogenic species that are common inhabitants soil plant rhizosphere. Many members the group in fact known as effective biocontrol agents pathogens growth promoters for these attitudes they great interest biotechnological applications. The antagonistic activity fluorescent is related to production several antibiotic compounds, lytic enzymes, lipopeptides siderophores. Several volatile organic compounds also synthesized by including different kinds molecules involved interactions with other organisms induction systemic responses plants. This review will focus on emitted P. so far identified, aim highlight role played interaction bacteria micro macro-organisms
Language: Английский
Citations
7
International Journal of Molecular Sciences, Journal Year: 2020, Volume and Issue: 21(23), P. 9257 - 9257
Published: Dec. 4, 2020
Eugenol, the generic name of 4-allyl-2-methoxyphenol, is major component clove essential oil, and has demonstrated relevant biological potential with well-known antimicrobial antioxidant actions. New O-alkylated eugenol derivatives, bearing a propyl chain terminals like hydrogen, hydroxyl, ester, chlorine, carboxylic acid, were synthesized in present work. These compounds later subjected to epoxidation conditions give corresponding oxiranes. All derivatives evaluated against their effect upon viability insect cell line Sf9 (Spodoptera frugiperda), demonstrating that structural changes elicit marked effects terms potency. In addition, most promising molecules for impact morphology, caspase-like activity, toxicity towards human cells. Some stood out cells, morphological assessment treated cells showing chromatin condensation fragmentation, which are compatible occurrence programmed death, confirmed by evaluation activity. findings point use as semisynthetic insecticides from plant natural products.
Language: Английский
Citations
43
Food Chemistry, Journal Year: 2021, Volume and Issue: 347, P. 129051 - 129051
Published: Jan. 13, 2021
Language: Английский
Citations
38