Multifunctional nanomedicines-enabled chemodynamic-synergized multimodal tumor therapy via Fenton and Fenton-like reactions DOI Creative Commons
Haiyan Gao,

Zhiping Cao,

Huanhuan Liu

et al.

Theranostics, Journal Year: 2023, Volume and Issue: 13(6), P. 1974 - 2014

Published: Jan. 1, 2023

Chemodynamic therapy (CDT) is well-known for using the tumor microenvironment to activate Fenton reaction or Fenton-like generate strong oxidative hydroxyl radicals tumor-specific treatment. It highly selective and safe, without depth limitation of tissue penetration, shows its potential as a new green therapeutic method with great clinical application. However, catalytic efficiency reagents involved in severely affected by inherent microenvironmental limitations tumors strict reaction-dependent conditions. With increasing application nanotechnology medical field, combined therapies based on different types functional nanomaterials have opened up avenues development next-generation CDT-enhanced system. This review will comprehensively exemplify representative results CDT other antitumor such chemotherapy, phototherapy, sonodynamic therapy, radiation magnetic hyperthermia immunotherapy, starvation gas gene oncosis combination thereof improving from hundreds latest literature, introduce strategies ingenious design nanomedicines regulations enhance further summarize challenges future perspective CDT-based multimodal anticancer therapy.

Language: Английский

Iron oxide nanoparticles in biological systems: Antibacterial and toxicology perspective DOI Creative Commons
Uchechukwu S. Ezealigo, Blessing N. Ezealigo, Samson O. Aisida

et al.

JCIS Open, Journal Year: 2021, Volume and Issue: 4, P. 100027 - 100027

Published: Oct. 20, 2021

There has been an increasing number of studies in magnetic nanoparticles with auspicious applications medicine. Among the oxides nanoparticles, iron oxide emerged as indispensable tool nanotechnology, particularly bio-nanotechnology. This is attributed to its exceptional properties such size, shape, magnetism, and biocompatibility. In this review, were exploited different model organisms ranging from prokaryotes eukaryotes, elucidating their cellular functions relative antibacterial activity, drug delivery, toxicity.

Language: Английский

Citations

128
Deep exploration of random forest model boosts the interpretability of machine learning studies of complicated immune responses and lung burden of nanoparticles DOI Creative Commons
Fubo Yu, Changhong Wei, Peng Deng

et al.

Science Advances, Journal Year: 2021, Volume and Issue: 7(22)

Published: May 26, 2021

A proposed machine learning method capable of mining feature interactions reveals the mechanisms bio-nano interactions.

Language: Английский

Citations

117
A critical review of heat transfer enhancement methods in the presence of porous media, nanofluids, and microorganisms DOI

Mohammadreza Habibishandiz,

M. Ziad Saghir

Thermal Science and Engineering Progress, Journal Year: 2022, Volume and Issue: 30, P. 101267 - 101267

Published: March 8, 2022

Language: Английский

Citations

104
A comprehensive overview of nanotechnology in sustainable agriculture DOI
Smriti Arora,

Gajiram Murmu,

Koel Mukherjee

et al.

Journal of Biotechnology, Journal Year: 2022, Volume and Issue: 355, P. 21 - 41

Published: June 22, 2022

Language: Английский

Citations

86
Multifunctional nanomedicines-enabled chemodynamic-synergized multimodal tumor therapy via Fenton and Fenton-like reactions DOI Creative Commons
Haiyan Gao,

Zhiping Cao,

Huanhuan Liu

et al.

Theranostics, Journal Year: 2023, Volume and Issue: 13(6), P. 1974 - 2014

Published: Jan. 1, 2023

Chemodynamic therapy (CDT) is well-known for using the tumor microenvironment to activate Fenton reaction or Fenton-like generate strong oxidative hydroxyl radicals tumor-specific treatment. It highly selective and safe, without depth limitation of tissue penetration, shows its potential as a new green therapeutic method with great clinical application. However, catalytic efficiency reagents involved in severely affected by inherent microenvironmental limitations tumors strict reaction-dependent conditions. With increasing application nanotechnology medical field, combined therapies based on different types functional nanomaterials have opened up avenues development next-generation CDT-enhanced system. This review will comprehensively exemplify representative results CDT other antitumor such chemotherapy, phototherapy, sonodynamic therapy, radiation magnetic hyperthermia immunotherapy, starvation gas gene oncosis combination thereof improving from hundreds latest literature, introduce strategies ingenious design nanomedicines regulations enhance further summarize challenges future perspective CDT-based multimodal anticancer therapy.

Language: Английский

Citations

65