Trace analysis of 61 natural and synthetic progestins in river water and sewage effluents by ultra-high performance liquid chromatography–tandem mass spectrometry DOI

Xiaoyan Shen,

Hong Chang, Dezhi Sun

et al.

Water Research, Journal Year: 2018, Volume and Issue: 133, P. 142 - 152

Published: Feb. 3, 2018

Language: Английский

Water Analysis: Emerging Contaminants and Current Issues DOI
Susan D. Richardson, Susana Y. Kimura

Analytical Chemistry, Journal Year: 2015, Volume and Issue: 88(1), P. 546 - 582

Published: Nov. 30, 2015

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTWater Analysis: Emerging Contaminants and Current IssuesSusan D. Richardson* Susana Y. KimuraView Author Information Department of Chemistry Biochemistry, University South Carolina, Columbia, Carolina 29208, United States*E-mail: [email protected]Cite this: Anal. Chem. 2016, 88, 1, 546–582Publication Date (Web):November 30, 2015Publication History Published online14 December 2015Published inissue 5 January 2016https://pubs.acs.org/doi/10.1021/acs.analchem.5b04493https://doi.org/10.1021/acs.analchem.5b04493review-articleACS PublicationsCopyright © 2015 American Chemical SocietyRequest reuse permissionsArticle Views12042Altmetric-Citations344LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum full text article downloads since November 2008 (both PDF HTML) across all institutions individuals. These metrics regularly updated to reflect usage leading up last few days.Citations number other articles citing this article, calculated by Crossref daily. Find more information about citation counts.The Altmetric Attention Score is a quantitative measure attention that research has received online. Clicking on donut icon will load page at altmetric.com with additional details score social media presence for given article. how calculated. Share Add toView InAdd Full Text ReferenceAdd Description ExportRISCitationCitation abstractCitation referencesMore Options onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Chlorine,Drinking water,Impurities,Pharmaceuticals,Wastewater Get e-Alerts

Language: Английский

Citations

379

Progestins as endocrine disrupters in aquatic ecosystems: Concentrations, effects and risk assessment DOI
Karl Fent

Environment International, Journal Year: 2015, Volume and Issue: 84, P. 115 - 130

Published: Aug. 11, 2015

Language: Английский

Citations

213

Steroid hormones in the aquatic environment DOI Creative Commons

Jasper Oreva Ojoghoro,

Mark D. Scrimshaw, John P. Sumpter

et al.

The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 792, P. 148306 - 148306

Published: June 16, 2021

Steroid hormones are extremely important natural in all vertebrates. They control a wide range of physiological processes, including osmoregulation, sexual maturity, reproduction and stress responses. In addition, many synthetic steroid widespread general use, both as human veterinary pharmaceuticals. Recent advances environmental analytical chemistry have enabled concentrations rivers to be determined. Many different hormones, synthetic, transformation products, been identified quantified, demonstrating that they aquatic contaminants. Laboratory ecotoxicology experiments, mainly conducted with fish, but also amphibians, shown some can adversely affect when present the water at low concentrations: even sub-ng/L. research has demonstrated mixtures inhibit each individual hormone is concentration below which it would not invoke measurable effect on its own. Limited field studies supported conclusions laboratory may pollutants significant concern. Further required identify main sources entering environment, better describe complex now known ubiquitously present, determine impacts environmentally-realistic vertebrates, especially fish. Only once completed robust risk assessment concluded.

Language: Английский

Citations

113

Progesterone: A Steroid with Wide Range of Effects in Physiology as Well as Human Medicine DOI Open Access
Lucie Kolátorová, Jana Vítků,

Josef Suchopár

et al.

International Journal of Molecular Sciences, Journal Year: 2022, Volume and Issue: 23(14), P. 7989 - 7989

Published: July 20, 2022

Progesterone is a steroid hormone traditionally linked with female fertility and pregnancy. In current reproductive medicine, progesterone its analogues play crucial roles. While the discovery of effects has long history, over recent decades, various novel actions this interesting have been documented, which neuro- immunoprotective activities are most widely discussed. Discoveries biological also driven research development in field used human medicine. Progestogen treatment predominately maintaining pregnancy, prevention preterm labor, gynecological pathologies, lowering negative menopause. However, there other medical fields where could find application future. The aim work to show mechanisms action metabolites, physiological pharmacological synthetic as well impacts production use on environment.

Language: Английский

Citations

86

Pharmaceuticals and personal care products: A critical review of the impacts on fish reproduction DOI
Matthew D. Overturf,

Jordan C. Anderson,

Zacharias Pandelides

et al.

Critical Reviews in Toxicology, Journal Year: 2015, Volume and Issue: 45(6), P. 469 - 491

Published: May 6, 2015

Research in environmental toxicology involving pharmaceuticals and personal care products (PPCPs) has increased greatly over the last 10–15 years. Much research been focused on endocrine-disrupting potential of PPCPs, as they relate to negative population impacts aquatic organisms. This review assesses current data reported effects PPCPs fish reproduction with an emphasis fecundity, a predictor effects. Studies both individual PPCP mixtures are presented. As majority studies reviewed demonstrate we these findings detected surface water concentrations compounds. Very few have conducted; however, need for types is warranted most likely exposed wild. In addition, laboratory field assessments wastewater treatment plant (WWTP) effluents, major source reviewed. provided from variable do not generally reproduction, or unable directly associate observed WWTP effluents. Finally, future considerations outlined provide avenue into understanding how wild populations affected by PPCPs. These aimed at determining adaptation multiple generations. global use continually rises, discern chronic exposure increased.

Language: Английский

Citations

116

Occurrence of Glucocorticoids, Mineralocorticoids, and Progestogens in Various Treated Wastewater, Rivers, and Streams DOI

Alexander Weizel,

Michael P. Schlüsener,

Georg Dierkes

et al.

Environmental Science & Technology, Journal Year: 2018, Volume and Issue: 52(9), P. 5296 - 5307

Published: March 26, 2018

In the current study a high sensitive analytical method was developed for determination of 60 steroids including glucocorticoids (GC), mineralocorticoids (MC), and progestogens (PG) in WWTP effluents surface water using liquid chromatography with tandem mass spectrometry detection (LC-MS/MS). The limits quantification (LOQ) ranged between 0.02 ng/L (cortisone) to 0.5 (drospirenone) from 0.05 (betamethasone) 5 (chlormadinone) treated wastewater. After optimization, applied effluents, rivers, streams around Germany. Numerous have been detected during sampling campaign predominant analytes all steroid types were determined. Moreover, occurrence dienogest, mometasone furoate, flumethasone pivalate, metabolites 6β-hydroxy triamcinolone acetonide, 7α-thiomethyl spironolactone, 11α-hydroxy canrenone is reported first time. addition, this revealed ubiquitous presence topically GC monoesters betamethasone propionate, valerate, 6α-methylprednisolone propionate water.

Language: Английский

Citations

110

Effects of endocrine disrupting chemicals on gonad development: Mechanistic insights from fish and mammals DOI Creative Commons
Géraldine Delbès, Mercedes Blázquez, Juan I. Fernandino

et al.

Environmental Research, Journal Year: 2021, Volume and Issue: 204, P. 112040 - 112040

Published: Sept. 9, 2021

Over the past century, evidence has emerged that endocrine disrupting chemicals (EDCs) have an impact on reproductive health. An increased frequency of disorders been observed worldwide in both wildlife and humans is correlated with accidental exposures to EDCs their production. Epidemiological experimental studies highlighted consequences early existence key windows sensitivity during development. Such life can immediate gonadal tract development, as well long-term health males females. Traditionally, were thought exert effects by modifying pathways controlling reproduction. Advances knowledge mechanisms regulating sex determination, differentiation development fish rodents led a better understanding molecular underlying exposure In this manuscript, we review developmental stages sensitive state which model affect these processes, based roadmap gonad specific mammals.

Language: Английский

Citations

104

Analysis of the sensitivity of in vitro bioassays for androgenic, progestagenic, glucocorticoid, thyroid and estrogenic activity: Suitability for drinking and environmental waters DOI
Frédéric D.L. Leusch, Peta A. Neale,

Armelle Hebert

et al.

Environment International, Journal Year: 2016, Volume and Issue: 99, P. 120 - 130

Published: Dec. 23, 2016

Language: Английский

Citations

89

A critical review on the distribution and ecological risk assessment of steroid hormones in the environment in China DOI

Ruyue Zhong,

Hongyan Zou, Jian Gao

et al.

The Science of The Total Environment, Journal Year: 2021, Volume and Issue: 786, P. 147452 - 147452

Published: April 30, 2021

Language: Английский

Citations

73

Determination of progestogens in surface and waste water using SPE extraction and LC-APCI/APPI-HRPS DOI
Oksana Golovko, Pavel Šauer, Ganna Fedorová

et al.

The Science of The Total Environment, Journal Year: 2018, Volume and Issue: 621, P. 1066 - 1073

Published: Feb. 2, 2018

Language: Английский

Citations

74