Journal of the American Chemical Society,
Journal Year:
2023,
Volume and Issue:
145(49), P. 26580 - 26591
Published: Nov. 29, 2023
The
precise
modulation
of
nanosheet
stacking
modes
introduces
unforeseen
properties
and
creates
momentous
applications
but
remains
a
challenge.
Herein,
we
proposed
strategy
using
bipolar
molecules
as
torque
wrenches
to
control
the
2-D
Zr-1,3,5-(4-carboxylphenyl)-benzene
metal-organic
framework
(2-D
Zr-BTB
MOF)
nanosheets.
phenyl-alkanes,
phenylmethane
(P-C1)
phenyl
ethane
(P-C2),
predominantly
instigated
rotational
Zr-BTB-P-C1
Zr-BTB-P-C2,
displaying
wide
angular
distribution.
This
included
orientations
at
0,
12,
18,
24°
Zr-BTB-P-C2
6,
15,
24,
30°.
With
reduced
polarity,
propane
(P-C3)
pentane
(P-C5)
introduced
steric
hindrance
facilitated
alkyl
hydrophobic
interactions
with
nanosheets,
primarily
resulting
in
eclipsed
for
Zr-BTB-P-C3
(64.8%)
Zr-BTB-P-C5
(93.3%)
angle
distributions
four
Zr-BTB-P
species
were
agreement
theoretical
calculations.
induction
mechanism
was
confirmed
by
sequential
guest
replacement
13C-1H
heteronuclear
correlation
(HETCOR).
In
addition,
single-particle
level,
first
observed
that
stacked
pores
exhibited
similar
desorption
rates
xylene
isomers,
while
showed
significant
discrepancy
xylenes.
Moreover,
nanosheets
stationary
phases
high
resolution,
selectivity,
repeatability,
durability
isomer
separation.
universality
proven
another
series
acetate-alkanes.
molecular
wrench
provides
an
opportunity
precisely
porous
Accounts of Chemical Research,
Journal Year:
2025,
Volume and Issue:
unknown
Published: Feb. 21, 2025
ConspectusMetal-organic
frameworks
(MOFs)
and
covalent
organic
(COFs),
as
emerging
porous
crystalline
materials,
have
attracted
remarkable
attention
in
chemistry,
physics,
materials
science.
MOFs
are
constructed
by
metal
clusters
(or
ions)
linkers
through
coordination
bonds,
while
COFs
prepared
pure
building
blocks
via
bonds.
Because
of
the
nature
linkages,
their
own
shortcomings.
Typically,
relatively
weak
bond
strengths
bonds
lead
to
poor
chemical
stability
MOFs,
which
limits
practical
implementations.
On
other
hand,
due
strong
exhibit
rather
higher
under
harsh
conditions,
compared
MOFs.
However,
lack
open
sites
restricts
functionalization
application.
Therefore,
it
is
hypothesized
that
"cream-skimming"
would
address
these
drawbacks
produce
a
new
class
material,
namely,
metal-organic
(CMOFs),
with
unprecedented
structural
complexity
advanced
functionality.
The
CMOFs
reveal
synthetic
approach
for
preparation
reticular
materials.
Specifically,
ions
reacted
chelating
ligands
assemble
complexes
or
functional
reactive
(e.g.,
-CHO,
-NH2),
can
be
further
connected
form
networked
structures
dynamic
chemistry
(DCC).
isolated
complex
cluster
precursors
show
enhanced
prevents
decomposition
rearrangements
during
self-assembly
process
CMOFs.
Since
topology
preassembled
nodes
well-defined,
structure
readily
predicted
upon
directed
networking
Unaccessible
from
unstable
highly
ion/clusters
traditional
conditions
DCC
approach.
Moreover,
synergize
advantages
COFs,
containing
active
ensuring
various
interesting
properties,
linkages
allow
high
even
conditions.
In
past
few
years,
our
group
has
specifically
focused
on
development
general
strategies
coinage
(Cu,
Ag,
Au)-based
cyclic
trinuclear
units
(CTUs)
DCC.
CTUs
trigonal
planar
functionalized
sites,
such
-NH2
react
afford
Notably,
also
features
properties
including
metallophilic
attraction,
π-acidity/basicity,
luminescence,
redox
activity
catalytic
activity,
incorporated
into
we
envision
promising
platforms
not
only
novel
but
potential
applications
many
research
fields
gas
absorption/separation,
sensing,
full-color
display,
catalysis,
energy,
biological
applications.
this
Account,
summarize
recent
studies
CMOFs,
starting
linkage
topological
design,
transformation,
morphological
control,
fields.
We
discuss
future
opportunities
challenges
rapidly
developed
field
hope
Account
may
promote
scientific
discoveries
CMOF-based
technologies
future.
Angewandte Chemie International Edition,
Journal Year:
2022,
Volume and Issue:
62(9)
Published: Dec. 27, 2022
The
synthesis
of
atomically
precise
copper
nanoclusters
(Cu-NCs)
with
high
chemical
stability
is
a
prerequisite
for
practical
applications,
yet
still
remains
long-standing
challenge.
Herein,
we
have
prepared
pyrazolate-protected
Cu-NC
(Cu8),
which
exhibited
exceptional
either
in
solid-state
or
solution.
crystals
Cu8
are
suitable
single
crystal
X-ray
diffraction
analysis
even
after
being
treated
boiling
water,
8
wt
%
H2
O2
,
concentrated
acid
(1
M
HCl)
saturated
base
(≈20
KOH),
respectively.
More
importantly,
the
structure
solution
also
remained
intact
toward
oxygen,
organic
(100
eq.
HOAc)
(400
dibutylamine)
confirmed
by
1
H
NMR
and
UV/Vis
analysis.
Taking
advantage
alkali-resistant,
illustrates
excellent
catalytic
activity
indolizines,
it
can
be
reused
at
least
10
cycles
without
losing
performance.
Angewandte Chemie International Edition,
Journal Year:
2023,
Volume and Issue:
63(8)
Published: Nov. 21, 2023
Nanomedicines
are
extensively
used
in
cancer
therapy.
Covalent
organic
frameworks
(COFs)
crystalline
porous
materials
with
several
benefits
for
therapy,
including
porosity,
design
flexibility,
functionalizability,
and
biocompatibility.
This
review
examines
the
use
of
COFs
therapy
from
perspective
reticular
chemistry
function-oriented
design.
First,
modification
sites
functionalization
methods
discussed,
followed
by
their
potential
as
multifunctional
nanoplatforms
tumor
targeting,
imaging,
integrating
functional
components.
Finally,
some
challenges
clinical
translation
presented
hope
promoting
development
COF-based
anticancer
nanomedicines
bringing
closer
to
trials.
Journal of the American Chemical Society,
Journal Year:
2023,
Volume and Issue:
145(49), P. 26580 - 26591
Published: Nov. 29, 2023
The
precise
modulation
of
nanosheet
stacking
modes
introduces
unforeseen
properties
and
creates
momentous
applications
but
remains
a
challenge.
Herein,
we
proposed
strategy
using
bipolar
molecules
as
torque
wrenches
to
control
the
2-D
Zr-1,3,5-(4-carboxylphenyl)-benzene
metal-organic
framework
(2-D
Zr-BTB
MOF)
nanosheets.
phenyl-alkanes,
phenylmethane
(P-C1)
phenyl
ethane
(P-C2),
predominantly
instigated
rotational
Zr-BTB-P-C1
Zr-BTB-P-C2,
displaying
wide
angular
distribution.
This
included
orientations
at
0,
12,
18,
24°
Zr-BTB-P-C2
6,
15,
24,
30°.
With
reduced
polarity,
propane
(P-C3)
pentane
(P-C5)
introduced
steric
hindrance
facilitated
alkyl
hydrophobic
interactions
with
nanosheets,
primarily
resulting
in
eclipsed
for
Zr-BTB-P-C3
(64.8%)
Zr-BTB-P-C5
(93.3%)
angle
distributions
four
Zr-BTB-P
species
were
agreement
theoretical
calculations.
induction
mechanism
was
confirmed
by
sequential
guest
replacement
13C-1H
heteronuclear
correlation
(HETCOR).
In
addition,
single-particle
level,
first
observed
that
stacked
pores
exhibited
similar
desorption
rates
xylene
isomers,
while
showed
significant
discrepancy
xylenes.
Moreover,
nanosheets
stationary
phases
high
resolution,
selectivity,
repeatability,
durability
isomer
separation.
universality
proven
another
series
acetate-alkanes.
molecular
wrench
provides
an
opportunity
precisely
porous
