Advances in highly doped upconversion nanoparticles

Nature Communications, Journal Year: 2018, Volume and Issue: 9(1)

Published: June 14, 2018

Lanthanide-doped upconversion nanoparticles (UCNPs) are capable of converting near-infra-red excitation into visible and ultraviolet emission. Their unique optical properties have advanced a broad range applications, such as fluorescent microscopy, deep-tissue bioimaging, nanomedicine, optogenetics, security labelling volumetric display. However, the constraint concentration quenching on luminescence has hampered nanoscience community to develop bright UCNPs with large number dopants. This review surveys recent advances in developing highly doped UCNPs, highlights strategies that bypass effect, discusses new well emerging applications enabled by these nanoparticles.

Language: Английский

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Rare-Earth Doping in Nanostructured Inorganic Materials

Chemical Reviews, Journal Year: 2022, Volume and Issue: 122(6), P. 5519 - 5603

Published: Jan. 6, 2022

Impurity doping is a promising method to impart new properties various materials. Due their unique optical, magnetic, and electrical properties, rare-earth ions have been extensively explored as active dopants in inorganic crystal lattices since the 18th century. Rare-earth can alter crystallographic phase, morphology, size, leading tunable optical responses of doped nanomaterials. Moreover, control ultimate electronic catalytic performance nanomaterials scalable manner, enabling significant improvements energy harvesting conversion. A better understanding critical role prerequisite for development an extensive repertoire functional practical applications. In this review, we highlight recent advances associated applications many fields. This review covers key criteria doping, including basic structures, lattice environments, strategies, well fundamental design principles that enhance electrical, catalytic, magnetic material. We also discuss future research directions challenges controlling

Language: Английский

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Recent progress of zero-dimensional luminescent metal halides

Chemical Society Reviews, Journal Year: 2021, Volume and Issue: 50(4), P. 2626 - 2662

Published: Jan. 1, 2021

This review provides in-depth insight into the structure–luminescence–application relationship of 0D all-inorganic/organic–inorganic hybrid metal halide luminescent materials.

Language: Английский

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Versatile Types of Inorganic/Organic NIR-IIa/IIb Fluorophores: From Strategic Design toward Molecular Imaging and Theranostics

Chemical Reviews, Journal Year: 2021, Volume and Issue: 122(1), P. 209 - 268

Published: Oct. 19, 2021

In vivo imaging in the second near-infrared window (NIR-II, 1000-1700 nm), which enables us to look deeply into living subjects, is producing marvelous opportunities for biomedical research and clinical applications. Very recently, there has been an upsurge of interdisciplinary studies focusing on developing versatile types inorganic/organic fluorophores that can be used noninvasive NIR-IIa/IIb (NIR-IIa, 1300-1400 nm; NIR-IIb, 1500-1700 nm) with near-zero tissue autofluorescence deeper penetration. This review provides overview reports published date design, properties, molecular imaging, theranostics fluorophores. First, we summarize design concepts up-to-date functional biomaterials, order single-walled carbon nanotubes (SWCNTs), quantum dots (QDs), rare-earth-doped nanoparticles (RENPs), organic (OFs). Then, these novel modalities applications brought by superior fluorescent properties are reviewed. Finally, challenges perspectives future translation, aiming at boosting application progress NIR-IIa NIR-IIb technology highlighted.

Language: Английский

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Standardizing luminescence nanothermometry for biomedical applications

Nanoscale, Journal Year: 2020, Volume and Issue: 12(27), P. 14405 - 14421

Published: Jan. 1, 2020

Luminescence nanothermometry enables accurate, remote, and all-optically-based thermal sensing. Notwithstanding its fast development, there are serious obstacles hindering reproducibility reliable quantitative assessment of nanothermometers, which impede the intentional design, optimization use these sensors. These issues include ambiguities or absence established universal rules for evaluation, incorrect assumptions about mechanisms behind response sensors as well dependence nanothermometers readout on external conditions host materials themselves. In this perspective article, we discuss problems propose a series standardization guidelines to be followed. This critical discourse constitutes first required step towards ubiquitous acceptance, by scientific community, luminescence thermometry tool remote temperature determination in numerous practical biomedical implementations.

Language: Английский

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NIR II-responsive photon upconversion through energy migration in an ytterbium sublattice

Nature Photonics, Journal Year: 2020, Volume and Issue: 14(12), P. 760 - 766

Published: Nov. 9, 2020

Language: Английский

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Er³⁺ Sensitized 1530 nm to 1180 nm Second Near‐Infrared Window Upconversion Nanocrystals for In Vivo Biosensing

Angewandte Chemie International Edition, Journal Year: 2018, Volume and Issue: 57(25), P. 7518 - 7522

Published: May 2, 2018

Fluorescent bioimaging in the second near-infrared window (NIR-II) can probe deep tissue with minimum auto-fluorescence and scattering. However, current NIR-II fluorophore-related biodetection vivo is only focused on direct disease lesion or organ bioimaging, it still a challenge to realize real-time dynamic biosensing. A new type of Er3+ sensitized upconversion nanoparticles are presented both excitation (1530 nm) emission (1180 located for The microneedle patch sensor inflammation detection developed based ratiometric fluorescence by combining effective H2 O2 sensing organic probes under Fenton catalysis Fe2+ . Owing large anti-Stokes shifting, low auto-fluorescence, scattering luminescence, be dynamically evaluated at very high resolution (200×200 μm).

Language: Английский

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Confining Excitation Energy in Er³⁺‐Sensitized Upconversion Nanocrystals through Tm³⁺‐Mediated Transient Energy Trapping

Angewandte Chemie International Edition, Journal Year: 2017, Volume and Issue: 56(26), P. 7605 - 7609

Published: May 4, 2017

A new class of lanthanide-doped upconversion nanoparticles are presented that without Yb3+ or Nd3+ sensitizers in the host lattice. In erbium-enriched core-shell NaErF4 :Tm (0.5 mol %)@NaYF4 nanoparticles, a high degree energy migration between Er3+ ions occurs to suppress effect concentration quenching upon surface coating. Unlike conventional -Er3+ system, ion can serve as both sensitizer and activator enable an effective process. Importantly, appropriate doping Tm3+ has been demonstrated further enhance luminescence through trapping. This endows resultant with bright red (about 700-fold enhancement) near-infrared is achievable under multiple excitation wavelengths. fundamental pathway mitigate effect, thus offering convenient method for red-emitting nanoprobes biological applications.

Language: Английский

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Recent Progress of Rare‐Earth Doped Upconversion Nanoparticles: Synthesis, Optimization, and Applications

Advanced Science, Journal Year: 2019, Volume and Issue: 6(22)

Published: Sept. 30, 2019

Abstract Upconversion is a nonlinear optical phenomenon that involves the emission of high‐energy photons by sequential absorption two or more low‐energy excitation photons. Due to their excellent physiochemical properties such as deep penetration depth, little damage samples, and high chemical stability, upconversion nanoparticles (UCNPs) are extensively applied in bioimaging, biosensing, theranostic, photochemical reactions. Here, recent achievements synthesis, optimization, applications UCNP‐based nanomaterials reviewed. The state‐of‐the‐art approaches synthesize UCNPs past few years introduced first, followed summary several strategies optimize emissive various UCNPs. Lastly, challenges future perspectives provided conclusion.

Language: Английский

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Quenching Pathways in NaYF₄:Er³⁺,Yb³⁺ Upconversion Nanocrystals

ACS Nano, Journal Year: 2018, Volume and Issue: 12(5), P. 4812 - 4823

Published: April 12, 2018

Lanthanide-doped upconversion (UC) phosphors absorb low-energy infrared light and convert it into higher-energy visible light. Despite over 10 years of development, has not been possible to synthesize nanocrystals (NCs) with UC efficiencies on a par what can be achieved in bulk materials. To guide the design realization more efficient NCs, better understanding is necessary loss pathways competing UC. Here we study excited-state dynamics workhorse material β-NaYF4 co-doped Yb3+ Er3+. For each energy levels involved infrared-to-visible UC, measure model competition between spontaneous emission, transfer lanthanide ions, other decay processes. An important quenching pathway high-energy vibrations solvent and/or ligand molecules surrounding as evidenced by effect resonances electronic transitions ions molecules. We present microscopic quantitative for NCs. It takes account cross-relaxation at high lanthanide-doping concentration well Förster resonance from excited states vibrational modes Our thereby provides insight inert-shell thickness required prevent Overall, strongest contribution reduced core–shell NCs comes near-infrared (Er3+: 4I11/2 Yb3+: 2F5/2), which likely due coupling OH– defects incorporated during synthesis.

Language: Английский

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