2D Black Phosphorus–Based Biomedical Applications

Advanced Functional Materials, Journal Year: 2019, Volume and Issue: 29(13)

Published: Feb. 4, 2019

Abstract Black phosphorus (BP) has increasingly attracted scientific attention since its first applications in biomedicine due to unique properties and excellent biocompatibility. In particular, layer‐dependent bandgap, moderate carrier mobility, large surface‐area‐to‐volume ratio, biodegradability, intrinsic photoacoustic properties, biocompatibility make it an ideal candidate for use photothermal therapy, photodynamic drug delivery, 3D printing, bioimaging, biosensing, theranostics, which are reviewed here. addition, the article discusses strategies overcome challenges related surface instability chemical degradation, a major obstacle application. This review not only provides comprehensive summary on BP preparation biomedical but also summarizes recent research future possibilities.

Language: Английский

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Black phosphorus composites with engineered interfaces for high-rate high-capacity lithium storage

Science, Journal Year: 2020, Volume and Issue: 370(6513), P. 192 - 197

Published: Oct. 9, 2020

Engineering phosphorous anodes A focus of battery research has been the development a range lithium, sodium, and potassium cathodes, but improving anode materials is also an important goal. Silicon shown some promise for replacing graphite because its exceptional capacity, dramatic volume change during lithiation-delithiation processes often leads to failure. Jin et al. developed composite that made black in core covered with swollen polyaniline. In contrast previous efforts, bonding between carbon allows high charging rate without sacrifices capacity cycling stability. Science , this issue p. 192

Language: Английский

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Fast Charging Anode Materials for Lithium‐Ion Batteries: Current Status and Perspectives

Advanced Functional Materials, Journal Year: 2022, Volume and Issue: 32(23)

Published: March 25, 2022

Abstract With the enormous development of electric vehicle market, fast charging battery technology is highly required. However, slow kinetics and lithium plating under condition traditional graphite anode hinder capability lithium‐ion batteries. To develop materials with rapid Li‐ions diffusion reaction has received widely attentions. This review summarizes current status in exploration materials, mainly including critical challenge achieving capability, inherent structures storage mechanisms various as well recent progress to improve rate performance involving morphology regulation, structure design, surface/interface modification, forming multiphase systems. Finally, challenges future directions developing Li‐ion batteries are highlighted.

Language: Английский

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Overcoming barriers in photodynamic therapy harnessing nano-formulation strategies

Chemical Society Reviews, Journal Year: 2021, Volume and Issue: 50(16), P. 9152 - 9201

Published: Jan. 1, 2021

Photodynamic therapy (PDT) has been extensively investigated for decades tumor treatment because of its non-invasiveness, spatiotemporal selectivity, lower side-effects, and immune activation ability.

Language: Английский

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Two-dimensional materials in biomedical, biosensing and sensing applications

Chemical Society Reviews, Journal Year: 2020, Volume and Issue: 50(1), P. 619 - 657

Published: Nov. 18, 2020

Two-dimensional (2D) materials are at the forefront of research. Here we overview their applications beyond graphene, such as transition metal dichalcogenides, monoelemental Xenes (including phosphorene and bismuthene), carbon nitrides, boron nitrides along with carbides (MXenes). We discuss usage in various biomedical environmental monitoring applications, from biosensors to therapeutic treatment agents, toxicity utility chemical sensing. highlight how a specific chemical, physical optical property 2D can influence performance bio/sensing, improve drug delivery photo/thermal therapy well affect toxicity. Such properties determined by crystal phases electrical conductivity, degree exfoliation, surface functionalization, strong photoluminescence, absorption near-infrared range high photothermal conversion efficiency. This review conveys great future all families materials, especially expanding materials' landscape new emerge germanene silicene.

Language: Английский

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S‐Scheme Heterojunction TiO₂/CdS Nanocomposite Nanofiber as H₂‐Production Photocatalyst

ChemCatChem, Journal Year: 2019, Volume and Issue: 11(24), P. 6301 - 6309

Published: Sept. 9, 2019

Abstract One‐dimensional (1D) nanostructured photocatalyst is a promising candidate for hydrogen (H 2 ) generation, which can be used to deal with the energy crisis. Herein, novel 1D TiO /CdS well‐hybridized nanofibers (NFs) were synthesized via in situ electrospinning method. These hybrid NFs showed high H ‐production rate of 2.32 mmol h −1 g an apparent quantum efficiency 10.14 %, was 35‐fold higher than that pristine NFs. X‐ray photoelectron spectroscopy (XPS) analysis and density functional theory calculation implied electrons transferred from CdS upon hybridization created internal electric field (IEF) pointing . This IEF drove photoexcited transfer toward light irradiation as revealed by irradiated XPS analysis, suggesting step‐scheme (S‐scheme) heterojunction formed nanohybrids greatly promoted separation electron‐hole pairs foster efficient photogeneration. The significant enhancement photocatalytic activity also benefited easy well‐distributed nanostructure nanohybrids. work presents method preparing production S‐scheme pathways.

Language: Английский

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In situ sprayed NIR-responsive, analgesic black phosphorus-based gel for diabetic ulcer treatment

Proceedings of the National Academy of Sciences, Journal Year: 2020, Volume and Issue: 117(46), P. 28667 - 28677

Published: Nov. 2, 2020

The treatment of diabetic ulcer (DU) remains a major clinical challenge due to the complex wound-healing milieu that features chronic wounds, impaired angiogenesis, persistent pain, bacterial infection, and exacerbated inflammation. A strategy effectively targets all these issues has proven elusive. Herein, we use smart black phosphorus (BP)-based gel with characteristics rapid formation near-infrared light (NIR) responsiveness address problems. in situ sprayed BP-based could act as 1) temporary, biomimetic "skin" temporarily shield tissue from external environment accelerate wound healing by promoting proliferation endothelial cells, vascularization, angiogenesis 2) drug "reservoir" store therapeutic BP pain-relieving lidocaine hydrochloride (Lid). Within several minutes NIR laser irradiation, generates local heat microcirculatory blood flow, mediate release loaded Lid for "on-demand" pain relief, eliminate bacteria, reduce Therefore, our study not only introduces concept sprayed, NIR-responsive relief targeting challenging diabetes but also provides proof-of-concept application materials DU treatment.

Language: Английский

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Marriage of black phosphorus and Cu2+ as effective photothermal agents for PET-guided combination cancer therapy

Nature Communications, Journal Year: 2020, Volume and Issue: 11(1)

Published: June 8, 2020

The use of photothermal agents (PTAs) in cancer therapy (PTT) has shown promising results clinical studies. rapid degradation PTAs may address safety concerns but usually limits the stability required for efficacious treatment. Conversely, with high degrade slowly. solutions that balance between and are rare. Here, we report inherent Cu2+-capturing ability black phosphorus (BP) can accelerate BP, while also enhancing stability. incorporation Cu2+ into BP@Cu nanostructures further enables chemodynamic (CDT)-enhanced PTT. Moreover, by employing 64Cu2+, positron emission tomography (PET) imaging be achieved vivo real-time quantitative tracking. Therefore, our study not only introduces an "ideal" PTA bypasses limitations PTAs, provides proof-of-concept application BP-based materials PET-guided, CDT-enhanced combination therapy.

Language: Английский

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Production of phosphorene nanoribbons

Nature, Journal Year: 2019, Volume and Issue: 568(7751), P. 216 - 220

Published: April 1, 2019

Language: Английский

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Property–Activity Relationship of Black Phosphorus at the Nano–Bio Interface: From Molecules to Organisms

Chemical Reviews, Journal Year: 2020, Volume and Issue: 120(4), P. 2288 - 2346

Published: Jan. 23, 2020

As a novel member of the two-dimensional nanomaterial family, mono- or few-layer black phosphorus (BP) with direct bandgap and high charge carrier mobility is promising in many applications such as microelectronic devices, photoelectronic energy technologies, catalysis agents. Due to its benign elemental composition (phosphorus), large surface area, electronic/photonic performances, chemical/biological activities, BP has also demonstrated great potential biomedical including biosensing, photothermal/photodynamic therapies, controlled drug releases, antibacterial uses. The nature BP-bio interface comprised dynamic contacts between nanomaterials (NMs) biological systems, where system interact. physicochemical interactions at nano-bio play critical role effects NMs. In this review, we discuss context unique properties that may affect effects. Herein, comprehensively reviewed recent studies on biomolecules, cells, animals summarized various cellular responses, inflammatory/immunological effects, well other outcomes depending own physical properties, exposure routes, biodistribution. addition, discussed environmental behaviors risks organisms BP. Based accumulating knowledge interfaces, review summarizes safer-by-design strategies change chemical stability interactions, which are tuning better understanding activity interfaces corresponding methods overcome challenges would promote future exploration terms bringing new practical applications.

Language: Английский

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