The gut microbiome in health and in disease DOI

Andrew B. Shreiner,

John Y. Kao, Vincent B. Young

et al.

Current Opinion in Gastroenterology, Journal Year: 2014, Volume and Issue: 31(1), P. 69 - 75

Published: Nov. 12, 2014

Recent technological advancements and expanded efforts have led to a tremendous growth in the collective knowledge of human microbiome. This review will highlight some important recent findings this area research.Studies described structure functional capacity bacterial microbiome healthy state variety disease states. Downstream analyses interactions between host its are starting provide mechanistic insights into these interactions. These data anticipated lead new opportunities for diagnosis, prognosis, treatment diseases.There is fast growing collection describing conditions available research community consideration further exploration. Ongoing characterize functions mechanisms underlying host-microbe better understanding role health disease.

Language: Английский

Role of the Microbiota in Immunity and Inflammation DOI Creative Commons
Yasmine Belkaid, Timothy W. Hand

Cell, Journal Year: 2014, Volume and Issue: 157(1), P. 121 - 141

Published: March 1, 2014

Language: Английский

Citations

4434

Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association DOI Creative Commons

Connie W. Tsao,

Aaron W. Aday, Zaid Almarzooq

et al.

Circulation, Journal Year: 2022, Volume and Issue: 145(8)

Published: Jan. 26, 2022

The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders, subclinical atherosclerosis, coronary failure, valvular venous peripheral artery disease) associated outcomes quality care, procedures, economic costs).

Language: Английский

Citations

4301

Gut microbiota in human metabolic health and disease DOI
Yong Fan, Oluf Pedersen

Nature Reviews Microbiology, Journal Year: 2020, Volume and Issue: 19(1), P. 55 - 71

Published: Sept. 4, 2020

Language: Английский

Citations

3264

Proteobacteria: microbial signature of dysbiosis in gut microbiota DOI

Na-Ri Shin,

Tae Woong Whon, Jin‐Woo Bae

et al.

Trends in biotechnology, Journal Year: 2015, Volume and Issue: 33(9), P. 496 - 503

Published: July 22, 2015

Language: Английский

Citations

3073

The Human Intestinal Microbiome in Health and Disease DOI
Susan V. Lynch, Oluf Pedersen

New England Journal of Medicine, Journal Year: 2016, Volume and Issue: 375(24), P. 2369 - 2379

Published: Dec. 14, 2016

The large majority of studies on the role microbiome in pathogenesis disease are correlative and preclinical; several have influenced clinical practice.

Language: Английский

Citations

3004

Dynamics and Stabilization of the Human Gut Microbiome during the First Year of Life DOI Creative Commons
Fredrik Bäckhed, Josefine Roswall, Yangqing Peng

et al.

Cell Host & Microbe, Journal Year: 2015, Volume and Issue: 17(5), P. 690 - 703

Published: May 1, 2015

Language: Английский

Citations

2838

Human Genetics Shape the Gut Microbiome DOI Creative Commons
Julia K. Goodrich, Jillian L. Waters, Angela C. Poole

et al.

Cell, Journal Year: 2014, Volume and Issue: 159(4), P. 789 - 799

Published: Nov. 1, 2014

Language: Английский

Citations

2818

Personalized Nutrition by Prediction of Glycemic Responses DOI Creative Commons
David Zeevi, Tal Korem, Niv Zmora

et al.

Cell, Journal Year: 2015, Volume and Issue: 163(5), P. 1079 - 1094

Published: Nov. 1, 2015

Language: Английский

Citations

2249

The gut microbiota and host health: a new clinical frontier DOI Creative Commons
Julian R. Marchesi, David H. Adams, Francesca Fava

et al.

Gut, Journal Year: 2015, Volume and Issue: 65(2), P. 330 - 339

Published: Sept. 2, 2015

Over the last 10-15 years, our understanding of composition and functions human gut microbiota has increased exponentially. To a large extent, this been due to new 'omic' technologies that have facilitated large-scale analysis genetic metabolic profile microbial community, revealing it be comparable in influence organ body offering possibility route for therapeutic intervention. Moreover, might more accurate think like an immune system: collection cells work unison with host can promote health but sometimes initiate disease. This review gives update on current knowledge area disorders, particular syndrome obesity-related disease, liver IBD colorectal cancer. The potential manipulating these disorders is assessed, examination latest most relevant evidence relating antibiotics, probiotics, prebiotics, polyphenols faecal transplantation.

Language: Английский

Citations

2033

Population-level analysis of gut microbiome variation DOI
Gwen Falony, Marie Joossens, Sara Vieira‐Silva

et al.

Science, Journal Year: 2016, Volume and Issue: 352(6285), P. 560 - 564

Published: April 28, 2016

“Normal” for the gut microbiota For benefit of future clinical studies, it is critical to establish what constitutes a “normal” microbiome, if exists at all. Through fecal samples and questionnaires, Falony et al. Zhernakova targeted general populations in Belgium Netherlands, respectively. Gut composition correlated with range factors including diet, use medication, red blood cell counts, chromogranin A, stool consistency. The data give some hints possible biomarkers normal communities. Science , this issue pp. 560 565

Language: Английский

Citations

2002