Experimental Evolution as a Tool to Investigate Natural Processes and Molecular Functions DOI Creative Commons
Philippe Remigi, Catherine Masson‐Boivin, Eduardo P. C. Rocha

et al.

Trends in Microbiology, Journal Year: 2019, Volume and Issue: 27(7), P. 623 - 634

Published: March 23, 2019

Language: Английский

Host and microbiome jointly contribute to environmental adaptation DOI Creative Commons
Carola Petersen, Inga K. Hamerich, Karen L. Adair

et al.

The ISME Journal, Journal Year: 2023, Volume and Issue: 17(11), P. 1953 - 1965

Published: Sept. 6, 2023

Abstract Most animals and plants have associated microorganisms, collectively referred to as their microbiomes, which can provide essential functions. Given importance, host-associated microbiomes the potential contribute substantially adaptation of host-microbiome assemblage (the “metaorganism”). Microbiomes may be especially important for rapid novel environments because change more rapidly than host genomes. However, it is not well understood how hosts jointly metaorganism adaptation. We developed a model system with disentangle contributions established replicate mesocosms containing nematode Caenorhabditis elegans co-cultured microorganisms in complex environment (laboratory compost). After approximately 30 generations (100 days), we harvested worm populations subjected them common garden experiment designed unravel impacts microbiome composition genetics on observed that took different trajectories mesocosm lines, some increasing fitness others decreasing, interactions between played an role these contrasting evolutionary paths. chose two exemplary (one increase one decrease) detailed study. For each example, identified specific changes both (for bacteria fungi) gene expression fitness. Our study provides experimental evidence influenced by microbiome.

Language: Английский

Citations

36
Gut microbes in metabolic disturbances. Promising role for therapeutic manipulations? DOI
Piero Portincasa, Mohamad Khalil,

Annarita Graziani

et al.

European Journal of Internal Medicine, Journal Year: 2023, Volume and Issue: 119, P. 13 - 30

Published: Oct. 4, 2023

Language: Английский

Citations

29
Enterobactin carries iron into C. elegans and mammalian intestinal cells by a mechanism independent of divalent metal transporter DMT1 DOI Creative Commons

Aileen K. Sewell,

Mingxue Cui,

Mengnan Zhu

et al.

Journal of Biological Chemistry, Journal Year: 2025, Volume and Issue: unknown, P. 108158 - 108158

Published: Jan. 1, 2025

Language: Английский

Citations

1
Ecology and evolution of facilitation among symbionts DOI Creative Commons
Flore Zélé, Sara Magalhães, Sonia Kéfi

et al.

Nature Communications, Journal Year: 2018, Volume and Issue: 9(1)

Published: Nov. 13, 2018

Facilitation occurs when one species positively impacts the fitness of another, and has predominantly been studied in free-living like plants. can also occur among symbiont (mutualistic or parasitic) strains, but equivalent studies are scarce. To advance an integrated view effect facilitation on ecology evolution, we review empirical evidence their underlying mechanisms, explore factors favouring its emergence, discuss consequences for virulence transmission. We argue that concept improve understanding evolutionary forces shaping communities effects hosts.

Language: Английский

Citations

71
Experimental Evolution as a Tool to Investigate Natural Processes and Molecular Functions DOI Creative Commons
Philippe Remigi, Catherine Masson‐Boivin, Eduardo P. C. Rocha

et al.

Trends in Microbiology, Journal Year: 2019, Volume and Issue: 27(7), P. 623 - 634

Published: March 23, 2019

Language: Английский

Citations

67