Benchmarking Spike Rate Inference in Population Calcium Imaging DOI Creative Commons

Lucas Theis,

Philipp Berens, Emmanouil Froudarakis

et al.

Neuron, Journal Year: 2016, Volume and Issue: 90(3), P. 471 - 482

Published: May 1, 2016

Language: Английский

Technologies for imaging neural activity in large volumes DOI
Na Ji, Jeremy Freeman, Spencer L. Smith

et al.

Nature Neuroscience, Journal Year: 2016, Volume and Issue: 19(9), P. 1154 - 1164

Published: Aug. 26, 2016

Language: Английский

Citations

274
Subcellular Imaging of Voltage and Calcium Signals Reveals Neural Processing In Vivo DOI Creative Commons
Helen H. Yang, François St-Pierre, Xulu Sun

et al.

Cell, Journal Year: 2016, Volume and Issue: 166(1), P. 245 - 257

Published: June 1, 2016

Language: Английский

Citations

263
Population imaging of neural activity in awake behaving mice DOI
Kiryl D. Piatkevich, Seth Bensussen,

Hua-an Tseng

et al.

Nature, Journal Year: 2019, Volume and Issue: 574(7778), P. 413 - 417

Published: Oct. 9, 2019

Language: Английский

Citations

234
A Photostable Silicon Rhodamine Platform for Optical Voltage Sensing DOI
Yi‐Lin Huang,

Alison Walker,

Evan W. Miller

et al.

Journal of the American Chemical Society, Journal Year: 2015, Volume and Issue: 137(33), P. 10767 - 10776

Published: Aug. 3, 2015

This paper describes the design and synthesis of a photostable, far-red to near-infrared (NIR) platform for optical voltage sensing. We developed new, sulfonated silicon rhodamine fluorophore integrated it with phenylenevinylene molecular wire create Berkeley Red Sensor Transmembrane potential, or BeRST 1 ("burst"). is first member class NIR sensitive dyes that make use photoinduced electron transfer (PeT) trigger interrogation membrane voltage. show displays bright, membrane-localized fluorescence in living cells, high photostability, excellent sensitivity neurons. Depolarization plasma results rapid increases (24% ΔF/F per 100 mV). can be used conjunction fluorescent stains organelles, Ca(2+) indicators, voltage-sensitive proteins. In addition, red-shifted spectral profile 1, relative commonly employed optogenetic actuators like ChannelRhodopsin2 (ChR2), which require blue light, enables electrophysiology The speed, sensitivity, photostability long-wavelength profiles useful noninvasive, dissection neuronal activity.

Language: Английский

Citations

228
Benchmarking Spike Rate Inference in Population Calcium Imaging DOI Creative Commons

Lucas Theis,

Philipp Berens, Emmanouil Froudarakis

et al.

Neuron, Journal Year: 2016, Volume and Issue: 90(3), P. 471 - 482

Published: May 1, 2016

Language: Английский

Citations

196