Stem cell therapy as a novel concept to combat CNS disorders DOI
Rahul Kumar, Srushti Mahajan, Ujala Gupta

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 175 - 206

Published: Oct. 11, 2024

Language: Английский

Mesenchymal stem cell-derived extracellular vesicles in systemic sclerosis: role and therapeutic directions DOI Creative Commons
Xuan Wang,

Jiaying Guo,

Qinggang Dai

et al.

Frontiers in Cell and Developmental Biology, Journal Year: 2024, Volume and Issue: 12

Published: Oct. 17, 2024

Systemic sclerosis (SSc) is a complex autoimmune disease with clinical symptoms of vascular damage, immune disorders, and fibrosis, presenting significant treatment challenges limited therapeutic options. Mesenchymal stem cell-derived extracellular vesicles (MSC-EVs) have been demonstrated in numerous studies as more effective than MSCs treating diseases. Recent demonstrate that MSC-EVs can significantly ameliorate the SSc mitigate pathological changes such injury, dysregulation, fibrosis. These findings underscore promising potential SSc. promote angiogenesis, modulate dysfunction, combat This article summarizes applications possible mechanisms for SSc, thereby offering novel direction

Language: Английский

Citations

1
Adipose-Derived Mesenchymal Stromal Cells: A Study on Safety and Efficacy in Ocular Inflammation DOI

Robert Rusch,

Emi Inagaki,

Hiroko Taniguchi

et al.

The Ocular Surface, Journal Year: 2024, Volume and Issue: 34, P. 523 - 534

Published: Oct. 1, 2024

Language: Английский

Citations

1
Interplay Between Skeletal and Hematopoietic Cells in the Bone Marrow Microenvironment in Homeostasis and Aging DOI
Emily R. Quarato, Noah Salama, Laura M. Calvi

et al.

Current Osteoporosis Reports, Journal Year: 2024, Volume and Issue: 22(4), P. 416 - 432

Published: May 23, 2024

Language: Английский

Citations

0
Therapeutic Prospects of Stem Cell-Derived EVs: Upcoming Avenues, Promises, and Challenges DOI

Yashvi Sharma,

Meenakshi Mendiratta,

Sujata Mohanty

et al.

Published: Jan. 1, 2024

Language: Английский

Citations

0
Mechanism and Application of Mesenchymal Stem Cells and Their Secreting Extracellular Vesicles in Regulating CD4<sup>+</sup>T Cells in Immune Diseases DOI Creative Commons

Zehua Lin,

Weisong Cai,

Yuechen Sun

et al.

Biophysics Reports, Journal Year: 2024, Volume and Issue: 10(6), P. 403 - 403

Published: Jan. 1, 2024

Mesenchymal stem cells (MSCs) show significant promise in treating immune diseases due to their ability differentiate into various cell types and immunomodulatory properties. However, the mechanisms by which MSCs regulate CD4

Language: Английский

Citations

0
The balance between helper T 17 and regulatory T cells in osteoimmunology and relevant research progress on bone tissue engineering DOI Creative Commons
Shuyu Zhu, Jing Zhou, Zhigang Xie

et al.

Immunity Inflammation and Disease, Journal Year: 2024, Volume and Issue: 12(9)

Published: Sept. 1, 2024

Abstract Background Bone regeneration is a well‐regulated dynamic process, of which the prominent role immune system on bone homeostasis more and revealed by recent research. Before fully activation remodeling cells, needs to clean up microenvironment in facilitating repair initiation. Furthermore, this must be maintained properly various mechanisms over entire process. Objective This review aims summarize T‐helper 17/Regulatory T cell (Th17/Treg) balance discuss relevant progress tissue engineering. Results The response early stages crucial, especially impact Th17/Treg osteoclasts, mesenchymal stem cells (MSCs), osteoblasts activity. By virtue these knowledge advancements, innovative approaches engineering, such as nano‐structures, hydrogel, exosomes, are designed influence thereby augment regeneration. Conclusion Targeting promising strategy for developing new treatments enhance regeneration, thus offering potential breakthroughs injury clinics.

Language: Английский

Citations

0
Stem cell therapy as a novel concept to combat CNS disorders DOI
Rahul Kumar, Srushti Mahajan, Ujala Gupta

et al.

Elsevier eBooks, Journal Year: 2024, Volume and Issue: unknown, P. 175 - 206

Published: Oct. 11, 2024

Language: Английский

Citations

0