Quasi-Isotropic High-Resolution Fourier Ptychographic Diffraction Tomography with Opposite Illuminations DOI
Ning Zhou, Jiasong Sun, Runnan Zhang

et al.

ACS Photonics, Journal Year: 2023, Volume and Issue: 10(8), P. 2461 - 2466

Published: May 22, 2023

Optical diffraction tomography (ODT) is a powerful tool for the study of unlabeled biological cells thanks to its unique capability measuring three-dimensional (3D) refractive index (RI) distribution samples quantitatively and noninvasively. In conventional transmission ODT, however, certain spatial frequency components along optical axis cannot be measured due limited angular coverage incident beam, resulting in poor axial resolution several times worse than lateral one. this Letter we propose new type ODT method, termed opposite illumination Fourier ptychographic (OI-FPDT), which produces almost isotropic by combining transmissive angle-scanning reflective wavelength-scanning. Without resorting interferometric detection, OI-FPDT requires an intensity-only measurement, forward backward scattered intensity images are synthesized space recover 3D RI based on iterative reconstruction algorithm. To best our knowledge, first time that near-isotropic (∼ 274 nm) result obtained non-interferometric sample motion-free manner. Results simulated cell phantom, tailor-made fiberglass, onion epidermal confirm validity proposed method.

Language: Английский

Adaptive optical quantitative phase imaging based on annular illumination Fourier ptychographic microscopy DOI Creative Commons
Yefeng Shu, Jiasong Sun,

Jiaming Lyu

et al.

PhotoniX, Journal Year: 2022, Volume and Issue: 3(1)

Published: Oct. 21, 2022

Abstract Quantitative phase imaging (QPI) has emerged as a valuable tool for biomedical research thanks to its unique capabilities quantifying optical thickness variation of living cells and tissues. Among many QPI methods, Fourier ptychographic microscopy (FPM) allows long-term label-free observation quantitative analysis large cell populations without compromising spatial temporal resolution. However, high spatio-temporal resolution over long-time scale (from hours days) remains critical challenge: optically inhomogeneous structure biological specimens well mechanical perturbations thermal fluctuations the microscope body all result in time-varying aberration focus drifts, significantly degrading performance study. Moreover, aberrations are sample- environment-dependent, cannot be compensated by fixed design, thus necessitating rapid dynamic correction process. Here, we report an adaptive method based on annular illumination FPM. In this method, matched configuration (i.e., numerical aperture (NA) strictly equals objective NA), which is key recovering low-frequency information, further utilized accurate characterization. By using only 6 low-resolution images captured with different angles matching NA 10x, 0.4 objective, recover high-resolution (synthetic 0.8) characterize real time, restoring optimum system adaptively. Applying our live-cell imaging, achieve diffraction-limited (full-pitch $$655\,nm$$ 655 n m at wavelength $$525\,nm$$ 525 ) across wide field view ( $$1.77\,mm^2$$ 1.77 2 extended period time.

Language: Английский

Citations

73

Analytical study of nonlinear models using a modified Schrödinger’s equation and logarithmic transformation DOI Creative Commons
Chaoyang Zhu, Sahar Ahmed Idris,

M.E.M. Abdalla

et al.

Results in Physics, Journal Year: 2023, Volume and Issue: 55, P. 107183 - 107183

Published: Nov. 12, 2023

Optical solitons are special waves that maintain their shape while traveling. Hence, solitary optical have great significance when it comes to representing pulse propagation through nonlinear partial differential equations. In our research, we uncovered unique solutions for the formation of wave patterns in equation Heisenberg ferromagnetic spin chain (HFSC). This aptly describes behavior electromagnetic contemporary magnetism. By employing innovative techniques based on logarithmic transformations and analytical methods, obtained various solution forms expressed a concise manner using elementary functions. We tested correctness these by substituting them directly into main equation. These recent discoveries provide novel perspectives complex realm as depicted this model. Moreover, since model finds applications fiber optic communications, fluid dynamics, other fields, implications broad. The utilized methods stand out being simple, reliable, capable creating fresh equations mathematical physics. research findings presented here showcase effectiveness applied reliably studying phenomena HFSC problems utilizing tools, scholars opportunity expand enhance understanding frameworks underlying real-world problems.

Language: Английский

Citations

58

Trace element pollution tracking in the complex multi-aquifer groundwater system of Al-Hassa oasis (Saudi Arabia) using spatial, chemometric and index-based techniques DOI
Sani I. Abba, Mohamed A. Yassin, Syed Muzzamil Hussain Shah

et al.

Environmental Research, Journal Year: 2024, Volume and Issue: 249, P. 118320 - 118320

Published: Feb. 6, 2024

Language: Английский

Citations

50

On new diverse variety analytical optical soliton solutions to the perturbed nonlinear Schrödinger equation DOI Creative Commons
Chaoyang Zhu,

Suhad Ali Osman Abdallah,

Shahram Rezapour

et al.

Results in Physics, Journal Year: 2023, Volume and Issue: 54, P. 107046 - 107046

Published: Oct. 6, 2023

This study focuses on investigating the optical soliton solutions for perturbed nonlinear Schrödinger equation involving Kerr nonlinearity. It should be noted that non-integrable nature of becomes apparent when law nonlinearity is absent. absence integrability significantly obstructs finding exact solutions. Our research utilizes an innovative analytical technique, modified generalized exponential rational function method, to derive new The we obtained are quite versatile and practical real-world applications. They expressed in terms elementary functions such as exponentials, trigonometric functions, hyperbolic functions. simplicity allows easy comprehension straightforward utilization various scenarios. We present a variety visualizations graphs enhance understanding physical behaviors exhibited by graphical outcomes give insights into evolution dynamics under conditions. shows technique's efficacy producing equation. explore possibility expanding method discover alternative partial differential equations arise within theory optics. approach offers systematic framework obtaining broad class wave equations. employed methodologies hold also potential advance field contribute development tackling these challenging

Language: Английский

Citations

48

Quantitative phase imaging based on holography: trends and new perspectives DOI Creative Commons

Zhengzhong Huang,

Liangcai Cao

Light Science & Applications, Journal Year: 2024, Volume and Issue: 13(1)

Published: June 27, 2024

Abstract In 1948, Dennis Gabor proposed the concept of holography, providing a pioneering solution to quantitative description optical wavefront. After 75 years development, holographic imaging has become powerful tool for wavefront measurement and phase imaging. The emergence this technology given fresh energy physics, biology, materials science. Digital holography (DH) possesses advantages wide-field, non-contact, precise, dynamic capability complex-waves. DH unique capabilities propagation fields by measuring light scattering with information. It offers visualization refractive index thickness distribution weak absorption samples, which plays vital role in pathophysiology various diseases characterization materials. provides possibility bridge gap between disciplines. is described complex amplitude. complex-value complex-domain reconstructed from intensity-value camera real-domain. Here, we regard process recording reconstruction as transformation real-domain, discuss mathematics physical principles reconstruction. We review underlying principles, technical approaches, breadth applications. conclude emerging challenges opportunities based on combining other methodologies that expand scope utility even further. multidisciplinary nature brings application experts together label-free cell analytical chemistry, clinical sciences, sensing, semiconductor production.

Language: Английский

Citations

34

Graphical, statistical and index-based techniques integrated for identifying the hydrochemical fingerprints and groundwater quality of In Salah, Algerian Sahara DOI
Boualem Bouselsal, Johnbosco C. Egbueri

Environmental Geochemistry and Health, Journal Year: 2024, Volume and Issue: 46(5)

Published: April 9, 2024

Language: Английский

Citations

29

Groundwater potential zone mapping using GIS and Remote Sensing based models for sustainable groundwater management DOI Creative Commons
Abdur Rehman, Fakhrul Islam, Aqil Tariq

et al.

Geocarto International, Journal Year: 2024, Volume and Issue: 39(1)

Published: Jan. 1, 2024

The present research is conducted in the southern region of Khyber Pakhtunkhwa, Pakistan, to identify groundwater potential zones (GWPZ). We used three models including Weight Evidence (WOE), Frequency Ratio (FR), and Information Value (IV) with twelve parameters (elevation, slope, aspect, curvature, drainage network, LULC, precipitation, geology, Lineament, NDVI, road, soil texture, that have been prepared integrated into ArcGIS 10.8. reliability applied models' results was validated using Area Under Receiver Operating Characteristics (AUROC). GWPZ were reclassified five classes, i.e. very low, medium, high, high zone. area occupied by mentioned classes WOE are low (10.14%), (19.58%), medium (26.75%), (27.10%), (16.40%), while FR (20.93%), (32.38%), (18.92%), (13.13%), (14.61%) IV (14.41%), (17.17%), (29.01%), (25.85%), High (13.53%). Success Rate Curve WOE, FR, 0.86, 0.91, 0.87, Predicted values 0.89, 0.93, 0.90, respectively. revealed all statistical performed well delineate GWPZ. However, use technique strongly encouraged evaluate GWPZ, its findings especially useful for managing resources urban planning. Our approaches assessing mapping can be any similar scenarios recommended as a helpful tool policymakers manage groundwater.

Language: Английский

Citations

22

Lens-free on-chip 3D microscopy based on wavelength-scanning Fourier ptychographic diffraction tomography DOI Creative Commons
Xuejuan Wu, Ning Zhou, Yang Chen

et al.

Light Science & Applications, Journal Year: 2024, Volume and Issue: 13(1)

Published: Sept. 5, 2024

Language: Английский

Citations

21

AI-driven projection tomography with multicore fibre-optic cell rotation DOI Creative Commons
Jiawei Sun, Bin Yang, Nektarios Koukourakis

et al.

Nature Communications, Journal Year: 2024, Volume and Issue: 15(1)

Published: Jan. 2, 2024

Optical tomography has emerged as a non-invasive imaging method, providing three-dimensional insights into subcellular structures and thereby enabling deeper understanding of cellular functions, interactions, processes. Conventional optical methods are constrained by limited illumination scanning range, leading to anisotropic resolution incomplete structures. To overcome this problem, we employ compact multi-core fibre-optic cell rotator system that facilitates precise manipulation cells within microfluidic chip, achieving full-angle projection with isotropic resolution. Moreover, demonstrate an AI-driven tomographic reconstruction workflow, which can be paradigm shift from conventional computational methods, often demanding manual processing, fully autonomous process. The performance the proposed rotation approach is validated through phantoms HL60 human cancer cells. versatility learning-based workflow paves way for its broad application across diverse modalities, including but not flow cytometry acoustic tomography. Therefore, propel advancements in biology, aiding inception pioneering therapeutics, augmenting early-stage diagnostics.

Language: Английский

Citations

19

Transport-of-intensity Fourier ptychographic diffraction tomography: defying the matched illumination condition DOI Creative Commons
Shun Zhou, Jiaji Li, Jiasong Sun

et al.

Optica, Journal Year: 2022, Volume and Issue: 9(12), P. 1362 - 1362

Published: Oct. 26, 2022

Optical diffraction tomography (ODT) is a promising label-free three-dimensional (3D) microscopic method capable of measuring the 3D refractive index (RI) distribution optically transparent samples (e.g., unlabeled biological cells). In recent years, non-interferometric ODT techniques have received increasing attention for their system simplicity, speckle-free imaging quality, and compatibility with existing microscopes. However, methods implementing measurements in high numerical aperture (NA) microscopy systems are often plagued by low-frequency missing problems—a consequence violating matched illumination condition. Here, we present transport-of-intensity Fourier ptychographic (TI-FPDT) to address this challenging issue combining angular diversity additional “transport intensity” measurements. TI-FPDT exploits defocused phase contrast circumvent stringent requirement on NA imposed It effectively overcomes reconstruction quality deterioration RI underestimation problems conventional FPDT, as demonstrated high-resolution tomographic various (including microspheres, USAF targets, HeLa cells, C2C12 Due its simplicity effectiveness, anticipated open new possibilities biomedical applications.

Language: Английский

Citations

39