Research Square (Research Square),
Journal Year:
2022,
Volume and Issue:
unknown
Published: May 23, 2022
Abstract
COVID-19
pandemic
emerged
as
a
very
challenging
issue
for
everybody.
Education
system
received
big
blow,
and
the
whole
was
transferred
into
virtual
mode.
Transition
from
online
to
offline
not
smooth
easy
After
initial
hick
ups,
students
have
become
comfortable,
with
classes
evaluations.
Post
Lockdown
again
time
of
transition,
were
finding
it
difficult
cope
up
changes.
This
research
deals
identification
various
matters
which
led
stress
anxiety
among
MBA
Students.
Sample
size
253
students.
Primary
data
collected
structured
questionnaire.
Exploratory
factor
analysis
carried
out,
in
order
identify
factors
affecting
level,
coping
post
Covid-19
academic
life.
BMC Psychiatry,
Journal Year:
2023,
Volume and Issue:
23(1)
Published: Aug. 7, 2023
Antenatal
depression
and
anxiety
symptoms
may
have
negative
consequences
for
both
mothers
offspring,
upward
trends
in
the
prevalence
of
these
were
especially
apparent
during
COVID-19
epidemic.
The
purpose
this
study
was
to
evaluate
relevant
factors
influencing
depressive
Chinese
pregnant
women
post-COVID-19
era.We
conducted
an
online
survey
1,963
Jiangsu
Province,
using
a
cross-sectional
design,
collected
their
general
demographic
data.
nine-item
Patient
Health
Questionnaire
9
(PHQ-9)
used
symptoms,
seven-item
Generalized
Anxiety
Disorder
7
(GAD-7)
measure
symptoms.The
reported
antenatal
combined
with
25.2%,
27.9%,
18.6%,
respectively.
Of
respondents,
moderate
severe
depression,
7.9%
7.7%,
Binary
logistic
regression
analysis
demonstrated
that
age,
low
level
education,
rural
area,
unemployment,
pregnancy
complications,
poor
marital
relationship,
fair
household
income
positively
association
(all
P
<
0.05).
proportion
reporting
third
trimester
1.91-fold
higher
than
first
trimester.
Parity
factor
0.05).In
era,
expected,
it
is
vital
establish
hospital,
community,
family
psychological
health
screening
systems
based
on
enhance
early
preventive
measures.
Medical Science Monitor,
Journal Year:
2023,
Volume and Issue:
29
Published: Jan. 19, 2023
BACKGROUND
The
coronavirus
disease
2019
(COVID-19)
pandemic
has
impacted
the
health-related
quality
of
life
(HRQoL)
and
mental
health
worldwide.
However,
its
impact
on
medical
students
in
Indonesia
not
been
well
documented.
This
study
aimed
to
evaluate
HRQoL
729
Indonesian
during
COVID-19
pandemic.
MATERIAL
AND
METHODS
We
conducted
a
cross-sectional
from
31
August
30
September
2021.
instrument
was
an
online
questionnaire
that
distributed
via
social
media
platforms.
12-item
short
form
version
2
(SF12v2)
used
measure
HRQoL,
21-item
Depression,
Anxiety,
Stress
Scale
(DASS-21)
health.
RESULTS
From
included
analyses,
37.3%
had
impaired
physical
component
66.9%
HRQoL.
determinants
were
students'
island
residence,
history
hospitalization,
family
member's
hospitalization
death
due
COVID-19.
Concerning
health,
prevalence
reported
symptoms
depression,
anxiety,
stress
45.4%,
65.2%,
60.9%,
respectively.
Sex,
method,
grade,
previous
severity,
comorbidities,
learning
experience,
isolation
identified
as
CONCLUSIONS
highlights
adverse
effects
students.
results
key
associations,
including
SARS-CoV-2
infection
comorbidities
experienced
by
students,
their
families,
grief
following
bereavement,
International Journal of Molecular Sciences,
Journal Year:
2022,
Volume and Issue:
23(20), P. 12448 - 12448
Published: Oct. 18, 2022
The
regular
reappearance
of
coronavirus
(CoV)
outbreaks
over
the
past
20
years
has
caused
significant
health
consequences
and
financial
burdens
worldwide.
most
recent
still
ongoing
novel
CoV
pandemic,
by
Severe
Acute
Respiratory
Syndrome
2
(SARS-CoV-2)
brought
a
range
devastating
consequences.
Due
to
exceptionally
fast
development
vaccines,
mortality
rate
virus
been
curbed
extent.
However,
limitations
vaccination
efficiency
applicability,
coupled
with
high
infection
rate,
emphasise
urgent
need
for
discovering
safe
effective
antivirals
against
SARS-CoV-2
suppressing
its
replication
or
attenuating
virulence.
Non-structural
protein
1
(nsp1),
unique
viral
conserved
leader
protein,
is
crucial
virulence
factor
causing
host
mRNA
degradation,
interferon
(IFN)
expression
antiviral
signalling
pathways.
In
view
essential
role
nsp1
in
life
cycle,
it
regarded
as
an
exploitable
target
drug
discovery.
Here,
we
report
variety
fragment
hits
N-terminal
domain
identified
fragment-based
screening
via
X-ray
crystallography.
We
also
determined
structure
at
atomic
resolution
(0.99
Å).
Binding
affinities
potential
stabilisation
were
orthogonal
biophysical
assays
such
microscale
thermophoresis
thermal
shift
assays.
two
ligand-binding
sites
on
nsp1,
one
deep
shallow
pocket,
which
are
not
between
three
medically
relevant
SARS,
MERS
coronaviruses.
Our
study
provides
excellent
starting
point
more
potent
nsp1-targeting
inhibitors
functional
studies
nsp1.
Healthcare,
Journal Year:
2023,
Volume and Issue:
11(6), P. 839 - 839
Published: March 13, 2023
As
a
creative
form
of
psychotherapy,
drama
appears
to
assist
individuals
in
the
COVID-19
pandemic
and
post-pandemic
period
altering
crisis
conditions
challenging
negative
perspectives.
Drama-based
intervention
is
presented
as
an
option
for
addressing
mental
health
issues
clinical
general
populations
by
utilising
various
multidisciplinary
sources,
such
psychodrama
role
playing.
In
this
study,
systematic
review
meta-analysis
were
employed
assess
impact
on
well-being
during
post-pandemic.
Four
electronic
databases
(PubMed,
Cochrane,
Web
Science,
ScienceDirect)
extensively
searched
from
December
2019
October
2022.
Quality
assessment
Risk
Bias
tool
Cochrane
Collaboration
performed.
Using
random
effect
model,
standardised
mean
difference
(SMD)
values
95%
confidence
intervals
(CI)
calculated.
final
analysis,
25
studies
involving
797
participants
included.
The
study
revealed
that
drama-based
interventions
have
potential
improve
(e.g.,
trauma-related
disorders)
psychological
well-being),
which
could
position
adjunctive
method
care.
This
original
offered
newer,
more
comprehensive
recommendations
based
evidence.
Translational Psychiatry,
Journal Year:
2022,
Volume and Issue:
12(1)
Published: Sept. 9, 2022
Abstract
Background
The
extent
and
severity
of
post-COVID-19
mental
health
symptoms
among
frontline
clinicians
are
not
clear.
This
study
compared
(i.e.,
depression,
anxiety,
insomnia
symptoms)
global
quality
life
(QOL)
after
the
first
COVID-19
outbreak
between
treating
non-COVID-19
clinicians.
Methods
cross-sectional,
comparative,
convenient-sampling
was
conducted
October
13
22,
2020,
which
five
months
in
China
brought
under
control.
symptoms,
QOL
were
assessed
using
Patient
Health
Questionnaire-9
items
(PHQ-9),
Generalized
Anxiety
Disorder
Scale—7
(GAD-7),
Insomnia
Severity
Index
(ISI),
World
Organization
Quality
Life
Questionnaire—brief
version
(WHOQOL-BREF),
respectively.
propensity
score
matching
(PSM)
method
used
to
identify
comparable
A
generalized
linear
model
(GLM)
assess
differences
PHQ-9,
GAD-7,
ISI,
scores
Results
In
total,
260
matched
non-
included.
Non-COVID-19
experienced
more
frequent
workplace
violence
(WPV)
than
(
χ
2
=
7.6,
p
0.006).
reported
higher
their
counterparts
(b
0.3,
0.042),
adjusting
for
WPV
experience.
similar
ISI
total
(all
values
>
0.05).
Conclusion
did
reveal
severe
It
is
possible
that
implementation
timely
appropriate
health,
social
financial
supports
could
have
prevented
worsening
China.
Emerging Science Journal,
Journal Year:
2022,
Volume and Issue:
6, P. 15 - 32
Published: Feb. 7, 2022
Objectives:
This
study
aimed
to
explore
the
six
cultural
dimensions
of
Geert
Hofstede
that
affect
perceptions
quality
life
in
26
European
countries
during
COVID-19
pandemic
(April
2020–March
2021):
(1)
Quality
life,
(2)
Democracy
and
trust,
(3)
Working
COVID-19,
(4)
Financial
situation,
(5)
Support
(6)
Health
care
COVID-19.
Many
studies
are
not
conclusive
on
which
national
culture
spread
death
rate
The
researchers,
therefore,
consider
studying
from
perception
can
prevent
its
contribute
security
people
affected
by
may
be
another
way
providing
information
those
stakeholders.
Method:
To
determine
aspects
Europeans
pandemic,
researchers
analyzed
data
through
stepwise
multiple
regression
analysis
predict
relationship
between
independent
variables
(cultural
dimensions)
dependent
(perceptions
life).
Findings:
It
was
found
with
higher
power
distance
uncertainty
avoidance
had
a
lower
several
dimensions,
mainly
Eastern
Latin
(France,
Italy,
Portugal,
Spain).
In
Nordic
or
Scandinavian
levels
indulgence,
were
more
satisfied
their
spite
epidemic.
Novelty/Improvement:The
results
inform
policy-makers
stakeholders
how
cultures
have
both
positive
(i.e.,
indulgent
long-term)
negative
(high
high
avoidance)
effects
pandemic.
There
should
short-term
measures
provide
equal
economic
public
health
assistance
reduce
anxiety
(reduce
avoidance),
medium-term
promote
education
training
prepare
for
new
modes
working
future
(decrease
long-term
cultivate
save
optimistic
happy,
mentally
physically
(increase
long
term
orientation
indulgence).
Doi:
10.28991/esj-2022-SPER-02
Full
Text:
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