Frontiers in Public Health,
Journal Year:
2023,
Volume and Issue:
11
Published: March 16, 2023
Psychological
disturbances
are
frequent
following
COVID-19.
However,
there
is
not
much
information
about
whether
pre-existing
psychological
disorders
associated
with
the
severity
and
evolution
of
We
aimed
to
explore
associations
between
regular
psychotropic
medication
use
(PM)
before
infection
as
a
proxy
for
mood
or
anxiety
COVID-19
recovery
trajectories.
used
data
from
Predi-COVID
study.
followed
adults,
tested
positive
SARS-CoV-2
collected
demographics,
clinical
characteristics,
comorbidities
daily
symptoms
14
days
after
inclusion.
calculated
score
based
on
16
modeled
latent
class
performed
polynomial
logistic
regression
PM
primary
exposure
different
trajectories
outcome.
included
791
participants,
51%
were
men,
5.3%
reported
infection.
identified
four
characterizing
dynamics:
"Almost
asymptomatic,"
"Quick
recovery,"
"Slow
"Persisting
symptoms".
With
fully
adjusted
model
age,
sex,
socioeconomic,
lifestyle
comorbidity,
we
observed
risks
being
in
more
severe
than
Asymptomatic":
recovery"
(relative
risk
(95%
confidence
intervals)
3.1
(2.7,
3.4),
5.2
(3.0,
9.2),
symptoms"11.7
(6.9,
19.6)
gradient
slow
no
first
days.
These
results
suggest
that
condition
increases
poorer
may
increase
Long
COVID.
Our
findings
can
help
personalize
care
people
Biomedicines,
Journal Year:
2022,
Volume and Issue:
10(5), P. 1068 - 1068
Published: May 4, 2022
SARS-CoV-2
virus
infection
is
the
cause
of
coronavirus
disease
2019
(COVID-19),
which
still
spreading
over
world.
The
manifestation
this
can
range
from
mild
to
severe
and
be
limited
in
time
(weeks)
or
persist
for
months
about
30–50%
patients.
COVID-19
considered
a
multiple
organ
dysfunction
syndrome
musculoskeletal
system
manifestations
are
beginning
absolute
importance
both
patients
recovering
infection.
Musculoskeletal
other
infections
include
loss
muscle
mass,
weakness,
fatigue
myalgia,
injury.
molecular
mechanisms
by
damage
skeletal
(SkM)
cells
not
yet
well
understood.
Sphingolipids
(SLs)
represent
an
important
class
eukaryotic
lipids
with
structural
functions
as
bioactive
molecules
able
modulate
crucial
processes,
including
inflammation
viral
In
last
two
decades,
several
reports
have
highlighted
role
SLs
modulating
SkM
cell
differentiation,
regeneration,
aging,
response
insulin,
contraction.
This
review
summarizes
consequences
on
potential
involvement
tissue
responses
particular,
we
highlight
sphingosine
1-phosphate
signaling
order
aid
prediction
novel
targets
preventing
and/or
treating
acute
long-term
COVID-19.
Brazilian Journal of Psychiatry,
Journal Year:
2023,
Volume and Issue:
unknown
Published: Jan. 1, 2023
To
examine
the
association
between
psychiatric
and
non-psychiatric
comorbidity
28-day
mortality
among
patients
with
disorders
COVID-19.We
performed
a
multicenter
observational
retrospective
cohort
study
of
adult
hospitalized
laboratory-confirmed
COVID-19
at
36
Greater
Paris
University
hospitals
(January
2020-May
2021)
(N=3,768).
First,
we
searched
for
different
subgroups
according
to
their
comorbidities
through
cluster
analysis.
Next,
compared
all-cause
rates
across
identified
clusters,
while
taking
into
account
sex,
age,
number
medical
conditions.We
found
5
clusters
distinct
patterns.
Twenty-eight-day
in
mood
was
significantly
lower
than
other
clusters.
There
were
no
significant
differences
clusters.All
conditions
may
be
associated
increased
COVID-19.
The
risk
death
might
line
potential
beneficial
effect
certain
antidepressants
COVID-19,
but
requires
further
research.
These
findings
help
identify
at-risk
who
should
benefit
from
vaccine
booster
prioritization
prevention
measures.
V M BEKHTEREV REVIEW OF PSYCHIATRY AND MEDICAL PSYCHOLOGY,
Journal Year:
2024,
Volume and Issue:
58(2), P. 79 - 88
Published: April 25, 2024
The
aim
of
this
study
is
to
examine
the
relationship
between
severity
and
duration
criteria
COVID-19
psychopharmacotherapy
administered
patients
in
within
a
psychiatric
hospital.
Materials
Methods.
We
analyzed
169
case
histories
involving
completed
clinical
cases
treatment
specialized
infectious
department
St.
Petersburg,
covering
period
from
May
2020
January
2021.
Correlation,
dispersion,
regression
analyses
were
employed
evaluate
severe
mild
progression
indicators,
as
well
persistent
SARS-CoV-2
viral
shedding.
assessed
laboratory
parameters
patients,
along
with
administered,
including
antidepressants,
antipsychotics,
acid
sphingomyelinase
inhibitors
(FIASMA-active
drugs).
Results.
Cardiovascular
diseases
emerged
predictor
when
combined
an
increasing
platelet-to-lymphocyte
ratio
(PLR),
risk
course
by
over
two-fold.
use
any
psychotropic
agents
was
associated
0.9%
increase
for
each
unit
systemic
inflammation
index
PLR,
specifically
intellectual
disability
(ICD-10
codes
F70-79),
compared
schizophrenia
F20-29).
High
PLR
values
FIASMA-active
drugs
prolonged
duration,
while
antidepressant
therapy
elevated
C-reactive
protein
levels
reduced
predicted
shedding
13.8%
variance.
Additional
consideration
nosology
disorders
model
increased
proportion
explained
variance
22.8%.
Conclusion.
Consideration
should
be
given
thymoanaleptic
individuals
during
periods
disease
incidence
leading
up
potential
infection,
it
may
serve
protective
factor
against
COVID-19.
Furthermore,
there
no
evidence
suggest
adverse
effects
antipsychotics
on
Further
research
required
investigate
psychopharmacological
nosologically
homogeneous
groups.
Frontiers in Public Health,
Journal Year:
2023,
Volume and Issue:
11
Published: March 16, 2023
Psychological
disturbances
are
frequent
following
COVID-19.
However,
there
is
not
much
information
about
whether
pre-existing
psychological
disorders
associated
with
the
severity
and
evolution
of
We
aimed
to
explore
associations
between
regular
psychotropic
medication
use
(PM)
before
infection
as
a
proxy
for
mood
or
anxiety
COVID-19
recovery
trajectories.
used
data
from
Predi-COVID
study.
followed
adults,
tested
positive
SARS-CoV-2
collected
demographics,
clinical
characteristics,
comorbidities
daily
symptoms
14
days
after
inclusion.
calculated
score
based
on
16
modeled
latent
class
performed
polynomial
logistic
regression
PM
primary
exposure
different
trajectories
outcome.
included
791
participants,
51%
were
men,
5.3%
reported
infection.
identified
four
characterizing
dynamics:
"Almost
asymptomatic,"
"Quick
recovery,"
"Slow
"Persisting
symptoms".
With
fully
adjusted
model
age,
sex,
socioeconomic,
lifestyle
comorbidity,
we
observed
risks
being
in
more
severe
than
Asymptomatic":
recovery"
(relative
risk
(95%
confidence
intervals)
3.1
(2.7,
3.4),
5.2
(3.0,
9.2),
symptoms"11.7
(6.9,
19.6)
gradient
slow
no
first
days.
These
results
suggest
that
condition
increases
poorer
may
increase
Long
COVID.
Our
findings
can
help
personalize
care
people
