Do probiotics and iron supplementation have any impact on element distribution in rat kidneys? - bioimaging by laser ablation inductively coupled plasma mass spectrometry DOI
Julia Frąckowiak, Izabela Komorowicz, Adam Sajnóg

et al.

Talanta, Journal Year: 2024, Volume and Issue: 283, P. 127112 - 127112

Published: Oct. 28, 2024

Language: Английский

Application prospects of ferroptosis in colorectal cancer DOI Creative Commons

Gen Yang,

Biyun Qian, Liya He

et al.

Cancer Cell International, Journal Year: 2025, Volume and Issue: 25(1)

Published: Feb. 21, 2025

Colorectal cancer (CRC) is a serious threat to human health with the third morbidity and second cancer-related mortality worldwide. It urgent explore more effective strategy for CRC because of acquired treatment resistance from non-surgical conventional therapies, including radiation, chemotherapy, targeted therapy immunotherapy. Ferroptosis novel form programmed cell death characterized by iron-dependent lipid peroxidation species (ROS) accumulation has been identified as promising target treatment, especially those resistance. In this review, we mainly summarize recent studies on influence regulation ferroptosis which (including gut microbiota) modulating metabolism iron, amino acid lipid. Thus analysis may provide potential targets inducing shed lights future application in CRC.

Language: Английский

Citations

0
Gut microbiota participates in polystyrene microplastics-induced defective implantation through impairing uterine receptivity DOI
Jiani Sun, Lulu Geng, Dan Zhou

et al.

Journal of Environmental Management, Journal Year: 2025, Volume and Issue: 380, P. 124997 - 124997

Published: March 17, 2025

Language: Английский

Citations

0
Design, Synthesis, and Biological Evaluation of RSL3-based GPX4 Degraders with Hydrophobic Tags DOI

Yao Ning,

Zeqi Zhu,

Yi‐Cheng Wang

et al.

European Journal of Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 277, P. 116719 - 116719

Published: July 27, 2024

Language: Английский

Citations

3
Ferroptosis in kidney disease: a bibliometric analysis from 2012 to 2024 DOI Creative Commons
Yuxin Hu, Jingyi Tang,

Hanzhang Hong

et al.

Frontiers in Pharmacology, Journal Year: 2025, Volume and Issue: 15

Published: Jan. 13, 2025

Ferroptosis, a novel concept of programmed cell death proposed in 2012, kidney disease, has garnered significant attention based on evidence abnormal iron deposition and lipid peroxidation damage the kidney. Our study aim to examine trends future research directions field ferroptosis so as further explore target or treatment strategy for clinical disease. A thorough survey using Web Science Core Collection, focusing literature published between 2012 2024 examining interaction disease was conducted. VOSviewer, CiteSpace, Biblioshiny were used in-depth scientometric visualized analyses. From 2024, total 2,244 articles met inclusion criteria final analysis. The number annual publications this area showed steady pattern at beginning decade. top 3 journals with highest publication output Renal Failure, Oxidative Medicine And Cellular Longevity, Biomedicine & Pharmacotherapy. China United States had publications. Central South University Guangzhou Medical most active influential institutions. Documents citation analysis suggested that Andreas Linkermann, Jolanta Malyszko, Alberto Ortiz are researchers, by Scott J. Dixon Jose Pedro Friedmann Angeli, cited article, more important drivers development field. Keywords associated glutathione, peroxidation, nitric oxide high frequency early studies. In recent years, however, there been shift towards biomarkers, inflammation necrosis, which indicate current area. global landscape from presented. Basic mechanism exploration renal fibrosis chronic may be hot spot future.

Language: Английский

Citations

0
Skin Aging and the Upcoming Role of Ferroptosis in Geroscience DOI Open Access
Rita Rezzani, Gaia Favero,

Giorgia Cominelli

et al.

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(15), P. 8238 - 8238

Published: July 28, 2024

The skin is considered the most important organ system in mammals, and as population ages, it to consider aging anti-aging therapeutic strategies. Exposure of various insults induces significant changes throughout our lives, differentiating a young adult from that an older adult. These are caused by combination intrinsic extrinsic aging. We report interactions between its metabolism, showing network due several factors. For example, iron nutrient for humans, but level increases with aging, inducing deleterious effects on cellular functions. Recently, was discovered ferroptosis, or iron-dependent cell death, linked diseases. pursuit new molecular targets ferroptosis has recently attracted attention. Prevention effective strategy treatment diseases, especially old age. However, pathological biological mechanisms underlying still not fully understood, diseases such melanoma autoimmune Only few basic studies regulated death exist, challenge turn into clinical applications.

Language: Английский

Citations

1
Do probiotics and iron supplementation have any impact on element distribution in rat kidneys? - bioimaging by laser ablation inductively coupled plasma mass spectrometry DOI
Julia Frąckowiak, Izabela Komorowicz, Adam Sajnóg

et al.

Talanta, Journal Year: 2024, Volume and Issue: 283, P. 127112 - 127112

Published: Oct. 28, 2024

Language: Английский

Citations

0