Oxidation of commercial antioxidants is driving increasing atmospheric abundance of organophosphate esters: Implication for global regulation

One Earth, Journal Year: 2023, Volume and Issue: 6(9), P. 1202 - 1212

Published: Aug. 25, 2023

Language: Английский

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Per- and polyfluoroalkyl substances and volatile methyl siloxanes in global air: Spatial and temporal trends

Environmental Pollution, Journal Year: 2023, Volume and Issue: 323, P. 121291 - 121291

Published: Feb. 14, 2023

The study reports on the atmospheric concentrations of per- and polyfluoroalkyl substances (PFAS) volatile methyl siloxanes (VMS) measured using sorbent-impregnated polyurethane foam disks (SIPs) passive air samplers. New results are reported for samples collected in 2017, which extends temporal trend information to period 2009-2017, 21 sites where SIPs have been deployed since 2009. Among neutral PFAS, fluorotelomer alcohols (FTOHs) had higher than perfluoroalkane sulfonamides (FOSAs) sulfonamido ethanols (FOSEs) with levels ND‒228, ND‒15.8, ND‒10.4 pg/m3, respectively. ionizable sum perfluoroalkyl carboxylic acids (PFCAs) sulfonic (PFSAs) were 0.128-781 6.85-124 Longer-chain i.e. C9-C14 relevant recent proposal by Canada a listing long-chain (C9-C21) PFCAs Stockholm Convention, also detected environment at all site categories including Arctic sites. Cyclic linear VMS ranged between 1.34‒452 0.01-12.1 ng/m3, respectively, showing dominance urban areas. Despite wide range observed across different categories, geometric means PFAS groups fairly similar when grouped according five United Nations regions. Variable trends (2009-2017) both VMS. PFOS, has listed Convention 2009, is still increasing tendencies several sites, indicating constant input from direct and/or indirect sources. These new data inform international chemicals management

Language: Английский

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Building the Environmental Chemical-Protein Interaction Network (eCPIN): An Exposome-Wide Strategy for Bioactive Chemical Contaminant Identification

Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 57(9), P. 3486 - 3495

Published: Feb. 24, 2023

Although advancements in nontargeted analysis have made it possible to detect hundreds of chemical contaminants a single run, the current environmental toxicology approaches lag behind, precluding transition from analytical chemistry efforts health risk assessment. We herein highlighted recently developed "top-down" bioanalytical method, protein Affinity Purification with Nontargeted Analysis (APNA), screen for bioactive at "exposome-wide" level. To achieve this, tagged functional is employed as "bait" directly isolate mixtures, which are further identified by analysis. Advantages this protein-guided approach, including discovery new ligands well targets known contaminants, were several case studies. Encouraged these successful applications, we proposed framework, i.e., Chemical-Protein Interaction Network (eCPIN), construct complete map 7 billion binary interactions between all (>350,000) and human proteins (∼20,000) via APNA. The eCPIN could be established three stages through strategically prioritizing ∼20,000 proteins, such focusing on 48 nuclear receptors (e.g., thyroid hormone receptors) first stage. will provide an unprecedented throughput screening exposome-wide level facilitate identification molecular initiating events proteome-wide

Language: Английский

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Opinion: Atmospheric multiphase chemistry – past, present, and future

Atmospheric chemistry and physics, Journal Year: 2023, Volume and Issue: 23(17), P. 9765 - 9785

Published: Sept. 4, 2023

Abstract. Multiphase chemistry occurs between chemicals in different atmospheric phases, typically involving gas–solid and gas–liquid interactions. The importance of multiphase has long been recognized. Its central role extends from acid precipitation stratospheric ozone depletion to its impact on the oxidizing capacity troposphere roles that aerosol particles play driving chemistry–climate interactions affecting human health. This opinion article briefly introduces subject tracks development before after start Atmospheric Chemistry Physics. Most focuses research opportunities challenges field. Central themes are a fundamental understanding at molecular level underpins ability accurately predict environmental change discipline is strongest when tightly connected modeling field observations.

Language: Английский

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Nontarget Identification of Novel Organophosphorus Flame Retardants and Plasticizers in Rainfall Runoffs and Agricultural Soils around a Plastic Recycling Industrial Park

Environmental Science & Technology, Journal Year: 2023, Volume and Issue: 57(34), P. 12794 - 12805

Published: Aug. 14, 2023

Plastic recycling and reprocessing activities may release organophosphate ester (OPE) flame retardants plasticizers into the surrounding environment. However, relevant contamination profiles impacts remain not well studied. This study investigated occurrence of 28 OPEs their metabolites (mOPEs) in rainfall runoffs agricultural soils around one largest plastic industrial parks North China identified novel organophosphorus compounds (NOPs) using high-resolution mass spectrometry-based nontarget analysis. Twenty twenty-seven were detected runoff water soil samples, with total concentrations 86.0–2491 ng/L 2.53–199 ng/g dw, respectively. Thirteen NOPs identified, which eight reported environment for first time, including a chlorine-containing OPE, an heterocycle, phosphite, three OPE metabolites, two oligomers. Triphenylphosphine oxide diphenylphosphinic acid occurred ubiquitously soils, up to 390 40.2 The downwind areas park showed elevated levels NOPs. contribution hydroxylated mOPEs was higher than runoffs. These findings suggest that are significant sources biotransformation further increase ecological human exposure risk.

Language: Английский

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