
Trends in Cognitive Sciences, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 1, 2024
Language: Английский
Trends in Cognitive Sciences, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 1, 2024
Language: Английский
Nature, Journal Year: 2025, Volume and Issue: unknown
Published: March 12, 2025
Abstract Navigating social environments is a fundamental challenge for the brain. It has been established that brain solves this problem, in part, by representing information an agent-centric manner; knowledge about others’ abilities or attitudes tagged to individuals such as ‘oneself’ ‘other’ 1–6 . This intuitive approach informed understanding of key nodes parts brain, dorsomedial prefrontal cortex (dmPFC) and anterior cingulate (ACC) 7–9 However, patterns combinations which might interact with one another important identities individuals. Here, four studies using functional magnetic resonance imaging, behavioural experiments group decision-making task, we show dmPFC ACC represent combinatorial possibilities interaction afforded given situation, they do so compressed format resembling basis functions used spatial, visual motor domains 10–12 The align types, opposed individual identities. Our results indicate there are deep analogies between abstract neural coding schemes domain construction our sense identity.
Language: Английский
Citations
3Nature, Journal Year: 2025, Volume and Issue: 639(8053), P. 153 - 161
Published: Jan. 8, 2025
Language: Английский
Citations
2Neuron, Journal Year: 2024, Volume and Issue: unknown
Published: Nov. 1, 2024
Remembering events is crucial to intelligent behavior. Flexible memory retrieval requires a cognitive map and supported by two key brain systems: hippocampal episodic (EM) prefrontal working (WM). Although an understanding of EM emerging, little understood WM beyond simple retrieval. We develop mathematical theory relating the algorithms representations unveiling duality between storing memories in synapses versus neural activity. This results formalism as structured, controllable subspaces (activity slots) representing dynamic maps without synaptic plasticity. Using networks, we elucidate differences, similarities, trade-offs algorithms. Lastly, show that tasks from list learning cue-dependent recall are unified activity slots. Our unify frontal temporal offer new for WM.
Language: Английский
Citations
4Nature reviews. Neuroscience, Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 7, 2025
Language: Английский
Citations
0bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown
Published: Jan. 10, 2025
Abstract How do humans integrate fragmented experiences into a coherent structure for novel inferences? Although offline replay is proposed to reorganize memories, whether it constructs an integrated cognitive map remains unclear. Using magnetoencephalography, we tracked neural activity as participants learned one-dimensional, pairwise rank relationships that together formed two-dimensional (2D) conceptual map, and then inferred unobserved relationships. Offline during rest piecemeal memories 2D representation, predicting future inference accuracy. This fast on-task correlated with grid-cell-like code, representing generalizable schema minimized effortful online computations. In contrast, slow focusing on trial-specific details, negatively grid-like codes performance. Together, builds efficient offline, reducing reliance deliberate computations online.
Language: Английский
Citations
0Current Biology, Journal Year: 2025, Volume and Issue: 35(2), P. R60 - R62
Published: Jan. 1, 2025
Language: Английский
Citations
0bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown
Published: March 1, 2025
Abstract Schemas allow efficient behavior in new situations, but reliance on them can impair flexibility when demands conflict, culminating psychopathology. Evidence implicates the orbitofrontal cortex (OFC) deploying schemas situations congruent with previously acquired knowledge. But how does this role affect learning of a conflicting behavioral schema? Here we addressed question by recording single-unit activity OFC rats odor problems identical external information orthogonal rules governing reward. Consistent schema formation, representations adapted to track underlying rules, and both performance encoding was faster subsequent than initial problems. Surprisingly however, rule reward changed, persistent representation prior correlated acquisition new. Thus, not source interference instead supported accurately independently representing old as acquired.
Language: Английский
Citations
0bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2025, Volume and Issue: unknown
Published: March 4, 2025
Abstract At the core of intelligence is proficiency in solving new problems, including those that differ dramatically from problems seen before. Problem-solving, turn, depends on goal-directed generation novel thoughts and behaviors 1 , which has been proposed to rely internal representations discrete units, or symbols, processes can recombine them into a large set possible composite 1–11 . Although this view influential formulating cognitive-level explanations behavior, definitive evidence for neuronal substrate symbols remained elusive. Here, we identify neural population encoding action symbols—internal, recombinable units motor behavior—localized specific area frontal cortex. In macaque monkeys performing drawing-like task designed assess recombination learned sequences, found behavioral three critical features indicate actions have an underlying symbolic representation: (i) invariance over low-level parameters; (ii) categorical structure, reflecting classes action; (iii) sequences. simultaneous recordings across motor, premotor, prefrontal cortex, planning-related activity ventral premotor cortex encodes manner that, like reflects invariance, recombination, properties indicating representation. Activity no other recorded exhibited combination properties. These findings reveal representation localized PMv, therefore putative cognitive operations.
Language: Английский
Citations
0Nature Neuroscience, Journal Year: 2025, Volume and Issue: unknown
Published: May 28, 2025
Language: Английский
Citations
0Artificial Intelligence Review, Journal Year: 2025, Volume and Issue: 58(9)
Published: June 4, 2025
Language: Английский
Citations
0