The neurocognitive correlates of brain entropy estimated by resting state fMRI DOI Creative Commons
Ze Wang

NeuroImage, Journal Year: 2021, Volume and Issue: 232, P. 117893 - 117893

Published: Feb. 21, 2021

The human brain exhibits large-scale spontaneous fluctuations that account for most of its total energy metabolism. Independent any overt function, this immense ongoing activity likely creates or maintains a potential functional reserve to facilitate normal function. An important property is the long-range temporal coherence, which can be characterized by resting state fMRI-based entropy mapping (BEN), relatively new method has gained increasing research interest. purpose study was leverage large fMRI and behavioral data publicly available from connectome project address three but still unknown questions: stability rsfMRI-derived BEN; relationship BEN latent reserve; associations neurocognition. Our results showed highly stable across time; in default mode network (DMN) executive control (ECN) related negative correlation education years; lower DMN/ECN corresponds higher fluid intelligence better task performance. These suggest temporally trait; may provide means measure bestows functionality enhanced education.

Language: Английский

A meta-analysis suggests that tACS improves cognition in healthy, aging, and psychiatric populations DOI
Shrey Grover, Renata Fayzullina, Breanna M. Bullard

et al.

Science Translational Medicine, Journal Year: 2023, Volume and Issue: 15(697)

Published: May 24, 2023

Transcranial alternating current stimulation (tACS) has attracted interest as a technique for causal investigations into how rhythmic fluctuations in brain neural activity influence cognition and promoting cognitive rehabilitation. We conducted systematic review meta-analysis of the effects tACS on function across 102 published studies, which included 2893 individuals healthy, aging, neuropsychiatric populations. A total 304 were extracted from these studies. found modest to moderate improvements with treatment that evident several domains, including working memory, long-term attention, executive control, fluid intelligence. Improvements generally stronger after completion ("offline" effects) than during ("online" effects). greater studies used flow models optimize or confirm neuromodulation targets by stimulating electric fields generated protocols. In targeting multiple regions concurrently, changed bidirectionally (improved decreased) according relative phase, alignment, two (in phase versus antiphase). also noted separately older adults illnesses. Overall, our findings contribute debate surrounding effectiveness rehabilitation, quantitatively demonstrate its potential, indicate further directions optimal clinical study design.

Language: Английский

Citations

65
Resolving the prefrontal mechanisms of adaptive cognitive behaviors: A cross-species perspective DOI Creative Commons
Ileana L. Hanganu‐Opatz, Thomas Klausberger, Torfi Sigurdsson

et al.

Neuron, Journal Year: 2023, Volume and Issue: 111(7), P. 1020 - 1036

Published: April 1, 2023

Language: Английский

Citations

50
Hyperedge overlap drives explosive transitions in systems with higher-order interactions DOI Creative Commons
Federico Malizia, Santiago Lamata-Otín, Mattia Frasca

et al.

Nature Communications, Journal Year: 2025, Volume and Issue: 16(1)

Published: Jan. 9, 2025

Recent studies have shown that novel collective behaviors emerge in complex systems due to the presence of higher-order interactions. However, how behavior a system is influenced by microscopic organization its interactions not fully understood. In this work, we introduce way quantify overlap among hyperedges network, and show real-world exhibit different levels intra-order hyperedge overlap. We then study two types dynamical processes on networks, namely contagion synchronization, finding plays universal role determining variety systems. Our results demonstrate alone does guarantee abrupt transitions. Rather, explosivity bistability require structure with low value Group can lead explosive onsets biological sociotechnological Here, authors it between these kind drives whether emergence synchrony epidemics shows up smoothly or abruptly.

Language: Английский

Citations

4
Reproducibility of EEG functional connectivity in Alzheimer’s disease DOI Creative Commons
Casper T. Briels, Deborah N. Schoonhoven, Cornelis J. Stam

et al.

Alzheimer s Research & Therapy, Journal Year: 2020, Volume and Issue: 12(1)

Published: June 3, 2020

Abstract Background Although numerous electroencephalogram (EEG) studies have described differences in functional connectivity Alzheimer’s disease (AD) compared to healthy subjects, there is no general consensus on the methodology of estimating AD. Inconsistent results are reported due multiple methodological factors such as diagnostic criteria, small sample sizes and use measures sensitive volume conduction. We aimed investigate reproducibility disease-associated effects by commonly used with respect amyloid, tau neurodegeneration (A/T/N) criteria. Methods Eyes-closed task-free 21-channel EEG was from patients probable AD subjective cognitive decline (SCD), form two cohorts. Artefact-free epochs were visually selected several (AEC(-c), coherence, imaginary PLV, PLI, wPLI) estimated five frequency bands. Functional between diagnoses using AN(C)OVA models correcting for sex, age and, additionally, relative power band. Another model predicted Mini-Mental State Exam (MMSE) score estimates. The analysis repeated a subpopulation fulfilling A/T/N after correction influencing factors. analyses second cohort. Results Two large cohorts formed (SCD/AD; n = 197/214 202/196). Reproducible found AEC-c alpha beta bands ( p 6.20 × 10 −7 , Cohen’s d − 0.53; 5.78 −4 0.37) PLI wPLI theta band 3.81 −8 0.59; 1.62 0.60, respectively). Only remained significant statistical bandwidth. In addition, correlated severity represented MMSE score. Conclusion choice measure can impact outcome Our indicate that bands, measured reproducible most valid terms factors, correlation preferable properties Phase-based conduction, showed

Language: Английский

Citations

125
Transcranial electrical stimulation nomenclature DOI
Marom Bikson, Zeinab Esmaeilpour,

Devin Adair

et al.

Brain stimulation, Journal Year: 2019, Volume and Issue: 12(6), P. 1349 - 1366

Published: July 17, 2019

Language: Английский

Citations

115
High-frequency neuromodulation improves obsessive–compulsive behavior DOI
Shrey Grover,

John A. Nguyen,

Vighnesh Viswanathan

et al.

Nature Medicine, Journal Year: 2021, Volume and Issue: 27(2), P. 232 - 238

Published: Jan. 18, 2021

Language: Английский

Citations

96
Synchronization and chimeras in a network of photosensitive FitzHugh–Nagumo neurons DOI
Iqtadar Hussain, Sajad Jafari, Dibakar Ghosh

et al.

Nonlinear Dynamics, Journal Year: 2021, Volume and Issue: 104(3), P. 2711 - 2721

Published: May 1, 2021

Language: Английский

Citations

90
Frontoparietal theta-gamma interactions track working memory enhancement with training and tDCS DOI Creative Commons
Kevin T. Jones, Elizabeth L. Johnson, Marian E. Berryhill

et al.

NeuroImage, Journal Year: 2020, Volume and Issue: 211, P. 116615 - 116615

Published: Feb. 7, 2020

Despite considerable interest in enhancing, preserving, and rehabilitating working memory (WM), efforts to elicit sustained behavioral improvements have been met with limited success. Here, we paired WM training transcranial direct current stimulation (tDCS) the frontoparietal network over four days. Active tDCS enhanced performance by modulating interactions between theta oscillations gamma activity, as measured pre- post-training high-density electroencephalography (EEG). Increased phase-amplitude coupling (PAC) prefrontal site temporo-parietal activity explained improvements, was most effective when occurred near peak. These results demonstrate for first time that tDCS-linked elicits lasting changes behavior optimizing oscillatory substrates of control.

Language: Английский

Citations

83
Cohort study into the neural correlates of postoperative delirium: the role of connectivity and slow-wave activity DOI Creative Commons
Sean Tanabe, Rosaleena Mohanty, Heidi Lindroth

et al.

British Journal of Anaesthesia, Journal Year: 2020, Volume and Issue: 125(1), P. 55 - 66

Published: June 1, 2020

Language: Английский

Citations

83
Past, Present, and Future of Non-invasive Brain Stimulation Approaches to Treat Cognitive Impairment in Neurodegenerative Diseases: Time for a Comprehensive Critical Review DOI Creative Commons
Clara Sanches, Chloé Stengel,

Juliette Godard

et al.

Frontiers in Aging Neuroscience, Journal Year: 2021, Volume and Issue: 12

Published: Jan. 20, 2021

Low birth rates and increasing life expectancy experienced by developed societies have placed an unprecedented pressure on governments the health system to deal effectively with human, social financial burden associated aging-related diseases. At present, ∼24 million people worldwide suffer from cognitive neurodegenerative diseases, a prevalence that doubles every five years. Pharmacological therapies training/rehabilitation generated temporary hope and, occasionally, proof of mild relief. Nonetheless, these approaches are yet demonstrate meaningful therapeutic impact changes in prognosis. We here review evidence gathered for nearly decade non-invasive brain stimulation (NIBS), less known strategy aiming limit decline conditions. Transcranial Magnetic Stimulation Direct Current Stimulation, two most popular NIBS technologies, use electrical fields non-invasively long-lastingly enhance excitability/activity key regions contributing relevant processes. The current comprehensive critical presents proof-of-concept outcomes eight prevalent pathologies affecting cognition: Alzheimer’s Disease, Parkinson’s Dementia Lewy Bodies, Primary Progressive Aphasias (PPA), behavioral variant Frontotemporal Dementia, Corticobasal Syndrome, Supranuclear Palsy, Posterior Cortical Atrophy. analyzed total 70 internationally published studies: 33 focusing disease, 19 PPA 18 remaining pathologies. benefit clinical significance remains inconclusive, particular given lack sufficient number double-blind placebo-controlled randomized trials using multiday regimes, heterogeneity protocols, adequate neuroimaging response biomarkers, able show lasting effects field promising but, make further progress, research efforts need take account latest anatomical neurophysiological features underlying deficits patient populations. Moreover, as development vivo biomarkers ongoing, allowing early diagnosis neuro-cognitive conditions, one could consider scenario which treatment will be personalized made part rehabilitation program, or useful potential adjunct drug since earliest stages suh Research should also integrate novel knowledge mechanisms constraints guiding magnetic cerebral tissues activity, incorporate principles information-based neurostimulation.

Language: Английский

Citations

79