Neuron,
Journal Year:
2023,
Volume and Issue:
111(24), P. 3911 - 3925
Published: Oct. 6, 2023
Understanding
how
individuals
form
and
maintain
strong
social
networks
has
emerged
as
a
significant
public
health
priority
result
of
the
increased
focus
on
epidemic
loneliness
myriad
protective
benefits
conferred
by
connection.
In
this
review,
we
highlight
psychological
neural
mechanisms
that
enable
us
to
connect
with
others,
which
in
turn
help
buffer
against
consequences
stress
isolation.
Central
process
is
experience
rewards
derived
from
positive
interactions,
encourage
sharing
perspectives
preferences
unite
individuals.
Sharing
affective
states
others
helps
align
our
understanding
world
another's,
thereby
continuing
reinforce
bonds
strengthen
relationships.
These
processes
depend
systems
supporting
reward
cognitive
function.
Lastly,
also
consider
limitations
associated
pursuing
healthy
connections
outline
potential
avenues
future
research.
Science,
Journal Year:
2023,
Volume and Issue:
382(6669), P. 399 - 404
Published: Oct. 26, 2023
Sexual,
parental,
and
aggressive
behaviors
are
central
to
the
reproductive
success
of
individuals
species
survival
thus
supported
by
hardwired
neural
circuits.
The
behavior
control
column
(RBCC),
which
comprises
medial
preoptic
nucleus
(MPN),
ventrolateral
part
ventromedial
hypothalamus
(VMHvl),
ventral
premammillary
(PMv),
is
essential
for
all
social
behaviors.
RBCC
integrates
diverse
hormonal
metabolic
cues
adjusts
an
animal's
physical
activity,
hence
chance
encounters.
further
engages
mesolimbic
dopamine
system
maintain
interest
reinforces
actions
that
time-locked
with
We
propose
brainstem
form
a
dual-control
generating
moment-to-moment
actions.
This
Review
summarizes
recent
progress
regarding
identities
cells
their
pathways
drive
different
aspects
Science,
Journal Year:
2025,
Volume and Issue:
387(6730)
Published: Jan. 9, 2025
Sociosexual
preference
is
critical
for
reproduction
and
survival.
However,
neural
mechanisms
encoding
social
decisions
on
sex
remain
unclear.
In
this
study,
we
show
that
both
male
female
mice
exhibit
but
shift
to
when
facing
survival
threats;
their
mediated
by
the
dimorphic
changes
in
excitability
of
ventral
tegmental
area
dopaminergic
(VTA
DA
)
neurons.
males,
VTA
projections
nucleus
accumbens
(NAc)
mediate
preference,
those
medial
preoptic
preference.
females,
firing-pattern
(phasic-like
versus
tonic-like)
alteration
-NAc
projection
determines
sociosexual
preferences.
These
findings
define
neurons
as
a
key
node
decision-making
reveal
sexually
circuit
underlying