Bonding against the odds: Male prairie vole response to the “widow effect” among females DOI
Santiago A. Forero, Alexander G. Ophir

Behavioural Processes, Journal Year: 2023, Volume and Issue: 213, P. 104968 - 104968

Published: Nov. 1, 2023

Language: Английский

Prairie voles as a model for adaptive reward remodeling following loss of a bonded partner DOI
Julie M. Sadino, Zoe R. Donaldson

Annals of the New York Academy of Sciences, Journal Year: 2024, Volume and Issue: 1535(1), P. 20 - 30

Published: April 9, 2024

Loss of a loved one is painful event that substantially elevates the risk for physical and mental illness impaired daily function. Socially monogamous prairie voles are laboratory-amenable rodents form life-long pair bonds exhibit distress upon partner separation, mirroring phenotypes seen in humans. These attributes make an excellent model studying biology loss. In this review, we highlight parallels between humans voles, focusing on reward system engagement during bonding As yearning unique feature differentiates loss from other negative states, posit which homeostatic mechanisms help to maintain disrupted loss, resulting impacts. Finally, synthesize studies delineate remodeling systems adaptation. The stalling these processes likely contributes prolonged grief disorder, diagnosis recently added Diagnostic Statistical Manual Psychiatry.

Language: Английский

Citations

2
Oxytocin, Vasopressin, and Sex Differences in Social Behavior. It’s Complicated! DOI
Sean L. Veney, Heather K. Caldwell

Masterclass in neuroendocrinology, Journal Year: 2024, Volume and Issue: unknown, P. 109 - 129

Published: Jan. 1, 2024

Language: Английский

Citations

1
Pair bond quality influences social conditioned place preference expression, passive coping behavior, and central oxytocin receptor expression following partner loss in male prairie voles DOI

Erika M. Vitale,

Amina H. Tbaba,

Sophia Sanchez

et al.

Social Neuroscience, Journal Year: 2024, Volume and Issue: unknown, P. 1 - 14

Published: Nov. 22, 2024

The dissolving of social bonds is disruptive and leads to increased stress responsivity a strong desire for reunion. oxytocin (OXT) system critical the formation attachments, such as pair bonds, also involved in recognition, memory, vigilance. Therefore, long-term changes OXT resulting from cohabitation bonding may contribute reunion-seeking behavior. Here, we employed conditioned place preference (SCPP) forced swim test (FST) examine sensitivity partner-associated contexts passive coping following period partner separation. We found that opposite-sex led SCPP only male prairie voles with their partner, this was maintained short-term loss bonded partner. Furthermore, males were separated displayed more stress-coping than those not lost suggesting differences vole mating tactics (i.e. bond or not) influence behavioral response Finally, OXTR binding reflect variation loss-related phenotypes based on different strategies.

Language: Английский

Citations

1
Vasotocin but not isotocin is involved in the emergence of the dominant-subordinate status in males of the weakly electric fish, Gymnotus omarorum DOI
Paula Pouso, Álvaro Cabana,

Virginia Francia

et al.

Hormones and Behavior, Journal Year: 2023, Volume and Issue: 158, P. 105446 - 105446

Published: Nov. 8, 2023

Language: Английский

Citations

3
Aging leads to sex-dependent effects on pair bonding and increased number of oxytocin-producing neurons in monogamous prairie voles DOI Creative Commons
Michael A. Kelberman,

Kelly E. Winther,

Yana M. Medvedeva

et al.

bioRxiv (Cold Spring Harbor Laboratory), Journal Year: 2024, Volume and Issue: unknown

Published: May 17, 2024

Abstract Pair bonds powerfully modulate health, which becomes particularly important when facing the detrimental effects of aging. To examine impact aging on relationship formation and response to loss, we examined behavior in 6-, 12-, 18-month male female prairie voles, a monogamous species that forms mating-based pair bonds. We found older males (18-months) bonded quicker than younger while similarly aged voles increased partner directed affiliative behaviors. Supporting sex differences bonding behaviors, were more likely sample both novel females display preference during initial 20 minutes test. Using separation study observed an erosion only 12-month females, but overall decrease partner-directed affiliation across all groups, not males. Finally, number oxytocin, vasopressin, cells paraventricular hypothalamus These results establish as model normal abnormal bonding. Highlights demonstrate accelerated bond increase huddling after 2 wks Bonds erode faster Female from tests is reflected free interaction The oxytocin

Language: Английский

Citations

0
Hypothalamic vasopressin neural densities are higher in male Mongolian gerbils after separation from a pair bond partner and may facilitate behavior to form a new bond DOI
Brandon A. Fricker, Jing Jiang,

C.J. Esquilin-Rodriguez

et al.

Behavioural Brain Research, Journal Year: 2024, Volume and Issue: 473, P. 115181 - 115181

Published: Aug. 6, 2024

Language: Английский

Citations

0
Egalitarian cooperation linked to central oxytocin levels in communal breeding house mice DOI Creative Commons
Stefan Fischer, Callum Duffield, William T. Swaney

et al.

Communications Biology, Journal Year: 2024, Volume and Issue: 7(1)

Published: Sept. 27, 2024

Language: Английский

Citations

0
Aging leads to sex-dependent effects on pair bonding and increased number of oxytocin-producing neurons in monogamous prairie voles DOI
Michael A. Kelberman,

Kelly E. Winther,

Yana M. Medvedeva

et al.

Hormones and Behavior, Journal Year: 2024, Volume and Issue: 166, P. 105647 - 105647

Published: Sept. 29, 2024

Language: Английский

Citations

0
Bonding against the odds: Male prairie vole response to the “widow effect” among females DOI
Santiago A. Forero, Alexander G. Ophir

Behavioural Processes, Journal Year: 2023, Volume and Issue: 213, P. 104968 - 104968

Published: Nov. 1, 2023

Language: Английский

Citations

1