Delivery of antibacterial agents for wound healing applications using polysaccharide-based scaffolds

Journal of Drug Delivery Science and Technology, Journal Year: 2023, Volume and Issue: 84, P. 104516 - 104516

Published: April 26, 2023

Language: Английский

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3D Printing of Polysaccharide-Based Hydrogel Scaffolds for Tissue Engineering Applications: A Review

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 270, P. 132123 - 132123

Published: May 17, 2024

Language: Английский

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Exploring advancements in polysaccharide-based approaches: The cornerstone of next-generation cartilage regeneration therapeutics

International Journal of Biological Macromolecules, Journal Year: 2025, Volume and Issue: unknown, P. 141352 - 141352

Published: Feb. 1, 2025

Language: Английский

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Active gellan gum/purple sweet potato composite films capable of monitoring pH variations

Food Hydrocolloids, Journal Year: 2017, Volume and Issue: 69, P. 491 - 502

Published: March 8, 2017

Language: Английский

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3D bioprinting of gellan gum and poly (ethylene glycol) diacrylate based hydrogels to produce human-scale constructs with high-fidelity

Materials & Design, Journal Year: 2018, Volume and Issue: 160, P. 486 - 495

Published: Sept. 25, 2018

3D bioprinting, a promising technology by precisely positioning cell-laden biomaterials to fabricate complex functional artificial tissues and organs, has potential applications in regenerative medicine drug discovery. However, the printing of large-scale constructs with high structural fidelity is still major challenge. One main bottlenecks development bioink materials. Herein, double network hydrogel that combines superior shear-thinning recovery properties gellan gum (GG) rapid UV cross-linking capability poly (ethylene glycol) diacrylate (PEGDA) was formulated for extrusion based bioprinting cells. Printability investigated rheological structure fidelity. Excellent enabled printed retain shape stably after deposition without additional support, making it possible subsequently crosslink mechanically property improvement permanent stabilization. Furthermore, human-scale tissue such as human ear nose were printed. BMSCs MC3T3-E1 cells encapsulated GG/PEGDA exhibited viable cell percentages above 87% during long-term culture 21 days. This study demonstrates significant print living organs.

Language: Английский

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Scaffolds for 3D in vitro culture of neural lineage cells

Acta Biomaterialia, Journal Year: 2017, Volume and Issue: 54, P. 1 - 20

Published: March 2, 2017

Language: Английский

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Gellan gum-based delivery systems of therapeutic agents and cells

Carbohydrate Polymers, Journal Year: 2019, Volume and Issue: 229, P. 115430 - 115430

Published: Oct. 18, 2019

Language: Английский

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Tree gum-based renewable materials: Sustainable applications in nanotechnology, biomedical and environmental fields

Biotechnology Advances, Journal Year: 2018, Volume and Issue: 36(7), P. 1984 - 2016

Published: Aug. 27, 2018

Language: Английский

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Gellan Fluid Gel as a Versatile Support Bath Material for Fluid Extrusion Bioprinting

ACS Applied Materials & Interfaces, Journal Year: 2019, Volume and Issue: 11(6), P. 5714 - 5726

Published: Jan. 15, 2019

Biomedical applications of three-dimensional (3D) printing demand complex hydrogel-based constructs laden with living cells. Advanced support materials facilitate the fabrication such constructs. This work demonstrates versatility and utility a gellan fluid gel as bath material for fabricating freeform 3D hydrogel from variety materials. Notably, can supply sensitive biological cross-linking agents enzymes to printed precursors mild covalent cross-linking. approach is suitable cell-laden gelatin-based in which mammalian cells form intercellular contacts within hours fabrication; cellular activity observed over several days In addition, compatible wide range ionic thermal conditions, makes it ionically cross-linked structures generated by alginate-based ink formulations well thermosensitive formed gelatin. Ultraviolet irradiation also demonstrated photoinitiated acrylated Furthermore, performance terms filament stability residual on found be comparable superior, respectively, previously reported

Language: Английский

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Biological Role of Gellan Gum in Improving Scaffold Drug Delivery, Cell Adhesion Properties for Tissue Engineering Applications

Molecules, Journal Year: 2019, Volume and Issue: 24(24), P. 4514 - 4514

Published: Dec. 10, 2019

Over the past few decades, gellan gum (GG) has attracted substantial research interest in several fields including biomedical and clinical applications. The GG highly versatile properties like easy bio-fabrication, tunable mechanical, cell adhesion, biocompatibility, biodegradability, drug delivery, is to functionalize. These have put forth as a promising material tissue engineering regenerative medicine fields. Nevertheless, alone poor mechanical strength, stability, high gelling temperature physiological conditions. However, physiochemical can be enhanced by blending them with other polymers chitosan, agar, sodium alginate, starch, cellulose, pullulan, polyvinyl chloride, xanthan gum, nanomaterials, gold, silver, or composites. In this review article, we discuss comprehensive overview different strategies for preparation of based biomaterial, hydrogels, scaffolds wound healing, antimicrobial activity, adhesion. addition, given special attention applications GG, which combined another natural, synthetic nanoparticles, composites materials. Overall, article clearly presents summary recent advances studies on

Language: Английский

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