Materials Chemistry Frontiers, Journal Year: 2021, Volume and Issue: 5(18), P. 6693 - 6717
Published: Jan. 1, 2021
This review summarizes recent progress in CTE studies focusing on understanding the mechanisms and general characteristics. Additionally, some interdisciplinary distinctive are discussed.
Language: Английский
Angewandte Chemie International Edition, Journal Year: 2020, Volume and Issue: 59(25), P. 9888 - 9907
Published: Feb. 12, 2020
Aggregation-induced emission (AIE) describes a photophysical phenomenon in which molecular aggregates exhibit stronger than the single molecules. Over course of last 20 years, AIE research has made great strides material development, mechanistic study and high-tech applications. The achievements demonstrate that show many properties functions are absent species. In this review, we summarize advances field its related areas. We specifically focus on new materials attained by beyond microscopic level. hope review will inspire more into ensembles at meso level lead to significant progress biological science.
Language: Английский
Citations
1140
Aggregate, Journal Year: 2020, Volume and Issue: 1(1), P. 80 - 106
Published: Dec. 1, 2020
Abstract Theranostics referring to the ingenious integration of diagnostics and therapeutics has garnered tremendous attention in these years as it provides a promising opportunity for modern personalized precision medicine. By virtue good biocompatibility, outstanding fluorescence property, easy processability functionalization, promoted photosensitizing efficiency, well facile construction multi‐modality theranostics, fluorophores with aggregation‐induced emission (AIE) characteristics exhibit inexhaustible vigorous vitality field theranostics. Numerous significant breakthroughs state‐of‐the‐art progression have been witnessed past few years. This review highlights aggregation‐enhanced superiorities AIE luminogens (AIEgens) disease theranostics mainly involving diagnostic imaging (fluorescence room temperature phosphorescence), therapeutic intervention (photodynamic therapy), feasibility based on experimental measurements theoretical simulations. Additionally, latest advanced developments AIEgens aspect corresponding strategies design highly effective AIE‐active through triggering aggregation formation are comprehensively summarized. Moreover, brief conclusion discussion current challenges future perspectives this area is further presented.
Language: Английский
Citations
436
Advanced Materials, Journal Year: 2020, Volume and Issue: 32(36)
Published: July 30, 2020
Abstract Molecular science entails the study of structures and properties materials at level single molecules or small interacting complexes molecules. Moving beyond well‐defined complexes, aggregates (i.e., irregular clusters many molecules) serve as a particularly useful form that often display modified wholly new compared to their molecular components. Some unique phenomena such polymorphic aggregates, aggregation‐induced symmetry breaking, cluster excitons are only identified in few examples exotic features. Here, by virtue flourishing research on emission, concept “aggregate science” is put forward fill gaps between aggregates. Structures aggregate scale also systematically summarized. The structure–property relationships established for expected contribute technological development. Ultimately, may become an interdisciplinary field serves general platform academic research.
Language: Английский
Citations
422
Advanced Materials, Journal Year: 2019, Volume and Issue: 32(1)
Published: Oct. 3, 2019
Precise design of fluorescent molecules with desired properties has enabled the rapid development many research fields. Among different types optically active materials, luminogens aggregation-induced emission (AIEgens) have attracted significant interest over past two decades. The negligible luminescence AIEgens as a molecular species and high brightness in aggregate states distinguish them from conventional dyes, which galvanized efforts to bring wide array multidisciplinary applications. Herein, useful principles emerging structure-property relationships for precise toward desirable using concrete examples are revealed. cutting-edge applications their excellent performance enabling new directions biomedical theranostics, optoelectronic devices, stimuli-responsive smart visualization physical processes also highlighted.
Language: Английский
Citations
414
Nature Communications, Journal Year: 2020, Volume and Issue: 11(1)
Published: March 9, 2020
Abstract Fluorescence imaging in near-infrared IIb (NIR-IIb, 1500–1700 nm) spectrum holds a great promise for tissue imaging. While few inorganic NIR-IIb fluorescent probes have been reported, their organic counterparts are still rarely developed, possibly due to the shortage of efficient materials with long emission wavelength. Herein, we propose molecular design philosophy explore pure fluorophores by manipulation effects twisted intramolecular charge transfer and aggregation-induced at morphological levels. An dye emitting up 1600 nm quantum yield 11.5% NIR-II region is developed. fluorescence blood vessels deeply-located intestinal tract live mice based on dyes achieved high clarity enhanced signal-to-background ratio. We hope this study will inspire further development evolution bio-imaging.
Language: Английский
Citations
369
Aggregate, Journal Year: 2021, Volume and Issue: 2(1), P. 95 - 113
Published: Jan. 22, 2021
Abstract Phototheranostics that concurrently and complementarily integrate real‐time diagnosis in situ therapeutic capabilities one platform has become the advancing edge of precision medicine. Organic agents possess merits facile preparation, high purity, tunable photophysical property, good biocompatibility, potential biodegradability, which have shown great promise for disease theranostics. This review summarizes recent achievements organic phototheranostic applications, especially rationally utilize energy dissipation pathways Jablonski diagram to modulate fluorescence emission, photoacoustic/photothermal production, photodynamic processes. Of particular interest are systems exhibiting huge differences aggregate state as compared with solution or single molecule form, during intramolecular motions play an important role regulating properties. The advances from such aspect biomedical applications including high‐resolution imaging, activatable imaging therapy, adaptive theranostics, image‐guided surgery, immunotherapy, afterglow discussed. A brief summary perspective this field also presented. We hope will be helpful researchers interested bioprobe design theranostic inspire new insights into linkage between science field.
Language: Английский
Citations
249
Advanced Functional Materials, Journal Year: 2019, Volume and Issue: 30(7)
Published: Dec. 18, 2019
Abstract The shortage of high quantum yield (QY) organic fluorophores in the second near‐infrared window (NIR‐II) has become a bottleneck bioimaging field. Now, simple strategy is proposed to address this: constitutional isomerization on basis molecular design philosophy aggregation‐induced emission. With combination backbone distortion and rotor twisting, resultant NIR‐II fluorophore 2TT‐ o C6B displays an emission peak at 1030 nm QY 11% nanoparticles, one highest reported so far. Control molecules confirm that distorted twisted rotors play equally important roles determining fluorescence properties fluorophores. To allow for targeting ability reach deeply located diseases, neutrophils (NEs) are used penetrate brain tissues accumulate inflammation site. Herein, it shown NEs carrying nanoparticles can blood‐brain‐barrier visualize through intact scalp skull. Notably, bright contributes significantly enhanced signal‐to‐background ratio 30.6
Language: Английский
Citations
237
Advanced Materials, Journal Year: 2022, Volume and Issue: 34(23)
Published: Jan. 16, 2022
Abstract Liquid crystals have been intensively studied as functional materials. Recently, integration of various disciplines has led to new directions in the design liquid‐crystalline materials fields energy, water, photonics, actuation, sensing, and biotechnology. Here, recent advances liquid based on polymers, supramolecular complexes, gels, colloids, inorganic‐based hybrids are reviewed, from strategies functionalization these interfaces. New insights into provided by significant progress advanced measurements computational simulations, which enhance materials, also discussed.
Language: Английский
Citations
236
Coordination Chemistry Reviews, Journal Year: 2020, Volume and Issue: 429, P. 213693 - 213693
Published: Dec. 17, 2020
Language: Английский
Citations
228
Nanomaterials, Journal Year: 2020, Volume and Issue: 10(2), P. 261 - 261
Published: Feb. 4, 2020
Recently, metal nanoclusters (MNCs) emerged as a new class of luminescent materials and have attracted tremendous interest in the area luminescence-related applications due to their excellent luminous properties (good photostability, large Stokes shift) inherent good biocompatibility. However, origin photoluminescence (PL) MNCs is still not fully understood, which has limited practical application. In this mini-review, focusing on photoemission emission MNCs, we simply review evolution mechanism models from pure metal-centered quantum confinement mechanics ligand-centered p band intermediate state (PBIS) model via transitional ligand-to-metal charge transfer (LMCT or LMMCT) compromise model.
Language: Английский
Citations
203