Carbon Dots for Forensic Applications: A Critical Review DOI Creative Commons
Amy Verhagen, Antonios Kelarakis

Nanomaterials, Journal Year: 2020, Volume and Issue: 10(8), P. 1535 - 1535

Published: Aug. 5, 2020

Owing to their superior fluorescence performance, inexpensive synthesis and nontoxic nature, carbon dots (C-dots) are systematically explored in a variety of applications; this review, we outline critically discuss recent trends with respect potential exploitation criminal investigation, forensic toxicology anti-counterfeit interventions. Capitalising on colour-tuneable behaviour (in the sense that they adopt different colours incident radiation), C-dot-based compositions ideal for visual enhancement latent fingerprints, affording improved contrast against multicoloured patterned backgrounds. As highly sensitive selective optical nanoprobes, C-dots show excellent analytical performance detecting biological compounds, drugs, explosives, heavy metals poisonous reactants. In addition, benefiting from versatile structural chemical composition, can be incorporated into ink polymeric formulations capable functioning as new generation cost-effective barcodes security nanotags object authentication applications. Translating these encouraging research outcomes real-life innovations significant social economic impact requires an open, multidisciplinary approach close synergy between materials scientists, biologists, investigators digital engineers.

Language: Английский

Delivering the power of nanomedicine to patients today DOI Creative Commons

Matthieu Germain,

Fanny Caputo,

Su Metcalfe

et al.

Journal of Controlled Release, Journal Year: 2020, Volume and Issue: 326, P. 164 - 171

Published: July 15, 2020

The situation of the COVID-19 pandemic reminds us that we permanently need high-value flexible solutions to urgent clinical needs including simplified diagnostic technologies suitable for use in field and delivering targeted therapeutics. From our perspective nanotechnology is revealed as a vital resource this, generic platform technical tackle complex medical challenges. It towards this focusing on nanomedicine take issue with Prof Park's recent editorial published Journal Controlled Release. Prof. Park argued last 15 years failed deliver promised innovative patients (Park, K. beginning end hype. Release, 2019; 305, 221-222 [1]. We, ETPN (European Technology Platform Nanomedicine) [2], respectfully disagree. In fact, more than 50 formulations currently market, approval 3 key products (e. g. Onpattro, Hensify Vyxeos), have demonstrated concretely able design overcome critical barriers conventional medicine unique manner, but also within cells new drug-free therapeutic effects by using pure physical modes action, therefore make difference lives. Furthermore, >400 trials are expecting bring novel (e.g. platforms nucleic acid delivery), alone or combination other enabling biotechnologies, microfluidics, advanced materials, biomaterials, smart systems, photonics, robotics, textiles, Big Data ICT (information & communication technologies) generally. However, agree " it time examine sources difficulty translation move forward ". But reaching goal, investments support promising should increase, not decrease. As recently encouraged EMA its roadmap 2025, create unity through common knowledge hub linking academia, industry, healthcare providers hopefully policy makers reduce current fragmentation standardization regulatory body landscape. We promote strategy cross-technology innovation, development high value low-cost solution answer unmet help most projects get better faster clinic. This global vision one chose encourage fifteen years. All actions be taken clear view mind, without any fanfare", focus "on what matters real life", which patient his/her quality life. overview achievements serves reinforce drive further expanding growing maturity healthcare, accelerating pace transformation great potential into tangible breakthroughs.

Language: Английский

Citations

308

Review—Nanostructured Materials-Based Nanosensors DOI Creative Commons
R. Abdel-Karim,

Y. Reda,

A. M. ABD‐ELFATTAH

et al.

Journal of The Electrochemical Society, Journal Year: 2020, Volume and Issue: 167(3), P. 037554 - 037554

Published: Jan. 2, 2020

Nanosensors are sensing devices with at least one of their dimensions being up to100 nm. In the field nanotechnology, nanosensors instrumental for (a) detecting physical and chemical changes, (b) monitoring biomolecules biochemical changes in cells, (c) measuring toxic polluting materials presented industry environment. can be classified according to energy source, structure applications. The nanostructured used manufacturing such as: nanoscale wires (capability high detection sensitivity), carbon nanotubes (very surface area electron conductivity), thin films, metal oxides nanoparticles, polymer biomaterials. aim this review is provide an overview all classifications nanosensors, showing characteristcs functioning mechanisms among various categories.

Language: Английский

Citations

244

Nanotechnology-Enabled Biosensors: A Review of Fundamentals, Design Principles, Materials, and Applications DOI Creative Commons
M. Ramesh,

R. Janani,

C. Deepa

et al.

Biosensors, Journal Year: 2022, Volume and Issue: 13(1), P. 40 - 40

Published: Dec. 27, 2022

Biosensors are modern engineering tools that can be widely used for various technological applications. In the recent past, biosensors have been in a broad application spectrum including industrial process control, military, environmental monitoring, health care, microbiology, and food quality control. also specifically monitoring pollution, detecting toxic elements’ presence, presence of bio-hazardous viruses or bacteria organic matter, biomolecule detection clinical diagnostics. Moreover, deep medical applications such as well-being chronic disease treatment, vitro examination studies screening infectious diseases early detection. The scope expanding use is very high owing to their inherent advantages ease use, scalability, simple manufacturing process. Biosensor technology more prevalent large-scale, low cost, enhanced field. Integration nanotechnology with has shown development path novel sensing mechanisms they enhance performance ability currently biosensors. Nanoscale dimensional integration promotes formulation rapid molecules along single biomolecules where evaluated analyzed critically. Nanomaterials nano-biosensors nanomaterials commonly include nanoparticles, nanowires, carbon nanotubes (CNTs), nanorods, quantum dots (QDs). possess color tunability, sensitivity, large surface area, carrier capacity, stability, thermal electrical conductivity. current review focuses on nanotechnology-enabled biosensors, fundamentals, architectural design. expands view materials fabricating probable

Language: Английский

Citations

175

Exploring the potential of nanosensors: A brief overview DOI Creative Commons
Mohd Javaid, Abid Haleem, Ravi Pratap Singh

et al.

Sensors International, Journal Year: 2021, Volume and Issue: 2, P. 100130 - 100130

Published: Jan. 1, 2021

Nanosensors are now being used to detect and monitor physical characteristics such as the temperature at nanoscale, with chemical species nanoparticles. It is nanoscale devices that transform quantities into signals detectable analysable. in medical, pollutant control, pathogens detection, monitoring processes of manufacturing transportation systems. This technology can identify specific cells molecular level deliver medicine development particular places body by measuring volume, concentration, movement speed, gravitational, electric, magnetic forces, pressure, temperature, etc. paper briefly discusses nanosensors their associated varieties sensing techniques, along advancements. Taxonomy for industrial perspectives recognition elements discussed diagrammatically. Furthermore, ten significant potentials identified discussed. Therefore, present review work may be a basis future research find consolidated report on potential various nanosensors.

Language: Английский

Citations

121

Nanosensors: Recent perspectives on attainments and future promise of downstream applications DOI
Tijjani Adam, Subash C. B. Gopinath

Process Biochemistry, Journal Year: 2022, Volume and Issue: 117, P. 153 - 173

Published: March 29, 2022

Language: Английский

Citations

70

Electrochemical sensing of analytes in saliva: Challenges, progress, and perspectives DOI
Ana Gomez Cardoso, Herlys Viltres, Greter A. Ortega

et al.

TrAC Trends in Analytical Chemistry, Journal Year: 2023, Volume and Issue: 160, P. 116965 - 116965

Published: Feb. 13, 2023

Language: Английский

Citations

48

Nanotechnology-based biomedical devices in the cancer diagnostics and therapy DOI
Junaid Tantray, Akhilesh Patel,

Hiba Parveen

et al.

Medical Oncology, Journal Year: 2025, Volume and Issue: 42(2)

Published: Jan. 20, 2025

Language: Английский

Citations

2

Nanomaterial-based fluorescent sensors for the detection of lead ions DOI

Harpreet Singh,

Amy Bamrah,

Sanjeev K. Bhardwaj

et al.

Journal of Hazardous Materials, Journal Year: 2020, Volume and Issue: 407, P. 124379 - 124379

Published: Nov. 2, 2020

Language: Английский

Citations

117

Electrospun Nanofibers: Materials, Synthesis Parameters, and Their Role in Sensing Applications DOI Creative Commons

Saraswathi Kailasa,

M. Sai Bhargava Reddy, Muni Raj Maurya

et al.

Macromolecular Materials and Engineering, Journal Year: 2021, Volume and Issue: 306(11)

Published: Sept. 16, 2021

Abstract Since the last decade, electrospinning is garnering more attention in scientific research community, industries, applications like sensing (glucose, H 2 O , dopamine, ascorbic acid, uric neurotransmitter, etc.), biomedical (wound dressing, wound healing, skin, nerve, bone tissue engineering, and drug delivery systems), water treatment, energy harvesting, storage applications. This review paper provides a brief overview of method, history electrospinning, factors affecting electrospun nanofibers, their morphology with different materials composites (metals, metal oxides, 2D material, polymers copolymers, carbon‐based materials, etc.) used technique optical spinning parameters. Moreover, this deliberates application nanofibers fibrous mats for (electrochemical, optical, fluorescence, colorimetric, mechanical, photoelectric, mass sensitive change, resistive, ultrasensitive, most illustrative representations. In end, challenges, opportunities new direction future progress are also discussed.

Language: Английский

Citations

100

Trends of nanotechnology in type 2 diabetes mellitus treatment DOI Creative Commons
Yannis V. Simos, Konstantinos Spyrou, Michaela Patila

et al.

Asian Journal of Pharmaceutical Sciences, Journal Year: 2020, Volume and Issue: 16(1), P. 62 - 76

Published: June 4, 2020

There are several therapeutic approaches in type 2 diabetes mellitus (T2DM). When diet and exercise fail to control hyperglycemia, patients forced start therapy with antidiabetic agents. However, these drugs present drawbacks that can affect the course of treatment. The major disadvantages current oral modalities for treatment T2DM mainly depicted low bioavailability immediate release drug, generating need an increase frequency dosing. In conjugation manifestation adverse side effects, patient compliance is reduced. Over past few years nanotechnology has found fertile ground development novel delivery potentially enhance anti-diabetic regimes efficacy. All efforts have been targeted towards two main vital steps: (a) protect drug by encapsulating it into a nano-carrier system (b) efficiently gradual as well controllable manner. only limited number studies published literature used

Language: Английский

Citations

86