Chem,
Journal Year:
2023,
Volume and Issue:
10(2), P. 504 - 543
Published: Oct. 16, 2023
Metal-organic
frameworks
(MOFs)
have
emerged
as
a
potential
platform
for
biomedical
applications
due
to
their
highly
tunable
porosities,
structural
diversity,
and
multi-functionality.
MOFs'
external
surface
modifications
endow
them
with
new
properties
functions,
such
hydrophilicity,
colloidal
stability,
controlled
payload
release,
specific
targeted
delivery,
biocompatibility.
These
attributes
greatly
improve
the
performance
use
of
MOFs
diagnosis
treatment
several
diseases.
In
this
review,
we
aim
offer
an
up-to-date
comprehensive
assessment
current
advances
in
development
functionalization
MOFs,
from
design
application.
This
review
summarizes
engineering
approaches,
highlighting
representative
examples
successful
healthcare
applications.
Finally,
discuss
remaining
challenges
limitations
field
while
foresighted
ideas
future
research
directions.
Angewandte Chemie International Edition,
Journal Year:
2023,
Volume and Issue:
62(34)
Published: May 12, 2023
Thermocatalysis
of
CO2
into
high
valuable
products
is
an
efficient
and
green
method
for
mitigating
global
warming
other
environmental
problems,
which
Noble-metal-free
metal-organic
frameworks
(MOFs)
are
one
the
most
promising
heterogeneous
catalysts
thermocatalysis,
many
excellent
researches
have
been
published.
Hence,
this
review
focuses
on
obtained
from
various
conversion
reactions
catalyzed
by
noble-metal-free
MOFs,
such
as
cyclic
carbonates,
oxazolidinones,
carboxylic
acids,
N-phenylformamide,
methanol,
ethanol,
methane.
We
classified
these
published
references
according
to
types
products,
analyzed
methods
improving
catalytic
efficiency
MOFs
in
reaction.
The
advantages
using
MOF
were
also
discussed
along
text.
This
concludes
with
future
perspectives
challenges
be
addressed
potential
research
directions.
believe
that
will
helpful
readers
attract
more
scientists
join
topic
conversion.
Materials & Design,
Journal Year:
2023,
Volume and Issue:
233, P. 112231 - 112231
Published: Aug. 9, 2023
Bacterial
infection
continues
to
be
one
of
the
biggest
threats
human
health.
The
therapeutic
effect
is
significantly
reduced
as
a
result
development
super-bacteria-resistant
bacteria
due
overuse
antibiotics
for
conventional
antimicrobial
treatment.
emergence
drug-resistant
makes
it
necessary
develop
new
treatments.
Following
successful
application
photothermal
therapy
in
field
oncology
treatment,
more
and
researchers
are
applying
treatments
achieving
important
results,
especially
treatment
bacterial
infections.
As
non-invasive
anti-infection
method,
has
advantages
broad-spectrum
properties,
short
period,
low
systemic
impact.
In
PTT,
efficacy
strongly
depends
on
different
laser
properties
choice
agents
(PTAs).
purpose
this
review
discuss
most
recent
developments
nanomaterials
that
antibacterial.
We
will
delve
into
principles
spectrum
PTAs
provide
summary
current
synthesis,
classification,
structural
features,
physicochemical
antibacterial
performance
research.
challenges
future
prospects
enhanced
cytotoxicity
investigated.
Chemical Engineering Journal,
Journal Year:
2022,
Volume and Issue:
457, P. 141176 - 141176
Published: Dec. 30, 2022
The
appeal
of
metal–organic
frameworks
(MOFs)
in
wastewater
treatment
is
tempered
by
their
polycrystalline,
powdery
state,
and
challenges
associated
with
deployment.
In
the
case
UiO-66,
one
most
stable
widely-used
MOFs,
a
low
tendency
for
removing
some
organic
contaminants
has
been
observed
on
top
mentioned
issues.
To
address
these
challenges,
herein,
we
take
two
complementary
steps,
i.e.,
hybridization
UiO-66
nanodiamond
(ND)
followed
integration
hybrid
nanoparticles
electrospun
polymeric
nanofibers
based
chitosan/polyvinyl
alcohol
(PVA).
We
present
electrospinning
polymer/MOFs
as
promising
technique
to
fabricate
highly
efficient
adsorbents
water
remediation.
use
chitosan/PVA
(ECPN)
versatile
host
MOF
that
remove
cationic
methylene
blue
anionic
Congo
red
dyes.
Four
nanofiber
composites
containing
thermally
oxidized
(TOND),
ND,
[email
protected]
are
utilized
unravel
effect
type
loading
dye
adsorption
capacity.
It
shown
incorporation
small
ECPN
significantly
enhaces
maximum
More
importantly,
rationally
engineered
exhibit
best
performance
adsorption;
instance,
an
80
%
increase
capacity,
from
769
1429
mg/g,
recorded
loaded
compared
unfilled
ECPN.
On
that,
designed
adsorbent
showed
appreciable
regeneration
ability
after
6
adsorption–desorption
cycles.
All
all,
this
study
offers
new
generation
advanced
materials
emerging
streams.
Analytical and Bioanalytical Chemistry,
Journal Year:
2023,
Volume and Issue:
415(11), P. 2005 - 2023
Published: Jan. 4, 2023
Abstract
The
deployment
of
metal–organic
frameworks
(MOFs)
in
a
plethora
analytical
and
bioanalytical
applications
is
growing
research
area.
Their
unique
properties
such
as
high
but
tunable
porosity,
well-defined
channels
or
pores,
ease
post-synthetic
modification
to
incorporate
additional
functional
units
make
them
ideal
candidates
for
sensing
applications.
This
possible
because
the
interaction
analytes
with
MOF
often
results
change
its
structure,
eventually
leading
intrinsic
physicochemical
which
then
transduced
into
measurable
signal.
porosity
allows
adsorption
very
efficiently,
while
pore
sizes/nature
and/or
installation
specific
recognition
groups
allow
modulating
affinity
towards
different
classes
compounds,
turn
lead
good
sensor
sensitivity
selectivity,
respectively.
Some
figures
are
given
illustrate
potential
MOF-based
sensors
most
relevant
application
fields,
future
challenges
opportunities
their
translation
from
academia
(i.e.,
laboratory
testing
properties)
industry
real-world
devices)
critically
discussed.
Graphical
abstract
Advanced Functional Materials,
Journal Year:
2023,
Volume and Issue:
33(12)
Published: Jan. 12, 2023
Abstract
Gene
therapy
holds
great
promise
as
a
biomedicine
for
treating
cancer,
viral
infection,
and
recessive
gene
disorders,
while
genetic
detection
has
been
used
disease
diagnosis
prevention.
The
appropriate
carrier
is
crucial
to
improve
the
delivery
efficiency
of
nucleic
acids.
Although
nonviral
vectors
have
developed,
their
poor
acid
loading
efficiency,
off‐target
toxicity,
immunogenicity
significantly
hamper
use.
Metal‐organic
frameworks
(MOFs)
attracted
lot
attention
owing
high
surface
areas
tunable
structures.
Recently,
nanometric
MOFs
are
shown
be
promising
in
although
at
an
early
stage
development.
This
review
focuses
on
highlighting
current
status
breakthroughs
MOF
use
delivery,
including
siRNA,
miRNA
mRNA
DNA
transfection,
well
probes
expression.
study
will
help
promote
clinical
transformation
application
modulation,
that
can
offer.
Advanced Functional Materials,
Journal Year:
2023,
Volume and Issue:
34(43)
Published: Nov. 21, 2023
Abstract
Metal–organic
framework
(MOF)
materials
are
gaining
significant
interest
in
biomedical
research,
owing
to
their
high
porosity,
crystallinity,
and
structural
compositional
diversity.
Their
versatile
hybrid
organic/inorganic
chemistry
endows
MOFs
with
the
capacity
retain
organic
(drug)
molecules,
metals,
gases,
effectively
channel
electrons
photons,
survive
harsh
physiological
conditions
such
as
low
pH,
even
protect
sensitive
biomolecules.
Extensive
preclinical
research
has
been
carried
out
treat
several
pathologies
and,
recently,
integration
other
stents
implants
demonstrated
promising
performance
regenerative
medicine.
However,
there
remains
a
gap
between
MOF
translation
into
clinically
societally
relevant
medicinal
products.
Here,
intrinsic
features
of
outlined
suitability
specific
applications
detoxification,
drug
gas
delivery,
or
(combination)
therapy
platforms
is
discussed.
Furthermore,
examples
how
have
engineered
evaluated
different
medical
indications,
including
cancer,
microbial,
inflammatory
diseases
described.
Finally,
challenges
facing
clinic
critically
examined,
goal
establishing
directions
more
realistic
approaches
that
can
bridge
translational
MOF‐containing
(nano)materials.
