Biomass Conversion and Biorefinery,
Journal Year:
2022,
Volume and Issue:
14(5), P. 6567 - 6580
Published: May 5, 2022
Abstract
Biosynthesis
of
antioxidant
nanoparticles
using
plant
extracts
is
a
simple,
rapid,
environmentally
friendly,
and
cost-effective
approach.
In
this
study,
in
vitro
copper
mixed
oxide
(CuO/Cu
2
O)
were
prepared
from
the
alcoholic
extract
Phoenix
Dactylifera
L.
different
aqueous
concentrations
CuSO
4
·5H
O.
The
composition,
crystallinity,
morphology,
particle
size
CuO/Cu
O
NPs
tuned
by
increasing
concentration
to
10
mM.
Ultraviolet–visible
(UV–Vis)
Fourier-transform
infrared
(FTIR)
spectroscopy
confirmed
reduction
formation
NPs.
X-ray
diffraction
(XRD)
crystalline
nature
with
crystallite
varying
18
35
nm.
Scanning
electron
micrographs
(SEM)
showed
that
have
spherical
morphology
sizes
ranging
25
100
best
phase
ratio
about
1:1
half-maximal
inhibitory
(IC
50
)
0.39
mg/ml,
an
iron-containing
reducing
power
(FRAP)
432
mg
EFeSO
/100
NPs,
total
capacity
(TAC)
65
EAA/gNPs.
results
suggest
synthesized
are
excellent
antioxidants
for
therapeutic
applications.
Graphical
abstract
Journal of Nanobiotechnology,
Journal Year:
2022,
Volume and Issue:
20(1)
Published: Aug. 31, 2022
Abstract
The
rapid
advancement
of
nanomedicine
and
nanoparticle
(NP)
materials
presents
novel
solutions
potentially
capable
revolutionizing
health
care
by
improving
efficacy,
bioavailability,
drug
targeting,
safety.
NPs
are
intriguing
when
considering
medical
applications
because
their
essential
unique
qualities,
including
a
significantly
higher
surface
to
mass
ratio,
quantum
properties,
the
potential
adsorb
transport
drugs
other
compounds.
However,
must
overcome
or
navigate
several
biological
barriers
human
body
successfully
deliver
at
precise
locations.
Engineering
carrier
biointerface
can
help
main
optimize
delivery
in
more
personalized
manner.
This
review
discusses
significant
heterogeneous
how
engineering
promote
carriers
prevail
over
hurdles
manner,
thus
ushering
era
Precision
Medicine.
We
also
summarize
nanomedicines'
current
advantages
disadvantages
administration,
from
natural/synthetic
sources
clinical
applications.
Additionally,
we
explore
innovative
NP
designs
used
both
non-personalized
customized
as
well
they
attain
therapeutic
strategy.
Pharmaceuticals,
Journal Year:
2022,
Volume and Issue:
15(4), P. 455 - 455
Published: April 8, 2022
Nanoparticles
(NPs)
are
elements
derived
from
a
cluster
of
atoms
with
one
or
more
dimensions
in
the
nanometer
scale
range
1-100
nm.
The
bio
nanofabrication
metallic
NPs
is
now
an
important
dynamic
area
research,
major
significance
applied
research.
Biogenic
synthesis
desirable
than
physical
and
chemical
due
to
its
eco-friendliness,
non-toxicity,
lower
energy
consumption,
multifunctional
nature.
Plants
outperform
microorganisms
as
reducing
agents
they
contain
large
secondary
biomolecules
that
accelerate
reduction
stability
NPs.
produced
can
then
be
studied
spectroscopically
(UV-Visible,
XRD,
Raman,
IR,
etc.)
microscopically
(SEM,
TEM,
AFM,
etc.).
biological
ion
oxide
nanoparticle
quick,
simple,
may
scaled
up
at
room
temperature
pressure.
rise
multi-drug
resistant
(MDR)
microbes
immoderate
use
antibiotics
non-infected
patients
cause
morbidity
mortality
humans.
contemporary
development
new
class
different
mechanisms
action
kill
crucial.
Metals
their
oxides
extremely
toxic
unprecedentedly
low
concentrations.
In
addition,
prevailing
infections
plants
animals
raising
significant
concerns
across
globe.
NPs'
wide
bioactivity
makes
them
ideal
antimicrobial
agricultural
medical
fields.
present
review
outlines
botanicals,
which
enables
metals
stabilized
form
even
after
ionization.
It
also
presents
valuable
database
on
biofunctionalization
synthesized
for
further
drug
development.
Green Chemistry,
Journal Year:
2022,
Volume and Issue:
24(14), P. 5429 - 5459
Published: Jan. 1, 2022
Organic
waste
valorisation
into
biopolymers
and
nanofillers
potentially
lowers
the
pressure
on
non-renewable
resources,
avoids
generation
of
waste-streams
opens
new
opportunities
to
develop
multifunctional
bio-based
products.
Pharmaceuticals,
Journal Year:
2022,
Volume and Issue:
15(9), P. 1057 - 1057
Published: Aug. 26, 2022
We
aimed
to
synthesize
zinc
oxide
nanoparticles
(ZnO
NPs)
using
the
endophytic
fungal
extract
of
Aspergillus
niger.
The
prepared
ZnO
NPs
were
characterized,
and
their
in
vitro
vivo
antibacterial
activity
was
investigated.
Isolated
fungus
identification
carried
out
18S
rRNA.
A.
niger
employed
for
green
synthesis
NPs.
elucidated
against
Staphylococcus
aureus
broth
microdilution
method
quantitative
real-time
polymerase
chain
reaction
(qRT-PCR).
Additionally,
a
systemic
infection
model
mice.
biosynthesized
showed
maximum
optical
density
at
380
nm
with
characteristic
peaks
on
Fourier-transform
infrared
spectrum.
X-ray
diffraction
pattern
highly
matched
standard
platform
crystals.
Energy-dispersive
analysis
confirmed
that
main
composition
oxygen
atoms.
Scanning
transmission
electron
microscopies
spherical
geometry
smooth
surface.
Zeta
potential
measurements
(26.6
±
0.56
mV)
verified
adequate
stability
Minimum
inhibitory
concentrations
S.
isolates
ranged
from
8
128
µg/mL.
revealed
antibiofilm
activity,
resulting
downregulation
tested
biofilm
genes
29.17%
isolates.
Regarding
experiment,
reduced
congestion
fibrosis
liver
spleen
tissues.
They
also
improved
function,
increased
survival
rate,
significantly
decreased
inflammatory
markers
(p
<
0.05).
synthesized
by
promising
action
Results in Chemistry,
Journal Year:
2024,
Volume and Issue:
7, P. 101368 - 101368
Published: Jan. 1, 2024
Zinc
oxide
nanoparticles
(ZnO
NPs)
exhibit
distinctive
characteristics,
making
them
highly
sought-after
in
many
sectors.
Nevertheless,
conventional
techniques
for
producing
ZnO-NPs
are
linked
to
environmental
and
health
hazards
due
toxic
substances.
In
this
review,
we
study
zinc
synthesized
from
plant
extracts
their
subsequent
biomedical
uses
detail.
Research
shows
that
several
different
employed
manufacturing
ZnO
nanoparticles.
Leaves,
fruits,
seeds,
roots,
complete
plants
all
included
these
extracts.
Phytochemicals
such
as
phenolic
compounds,
alkaloids,
flavonoids,
terpenoids
a
part
of
biological
matrices.
compounds
show
bioreduction
mechanism,
act
stabilizing
reducing
agent.
The
attributes
(NPs),
including
size,
shape,
crystallinity,
may
be
altered
by
adjusting
the
extract
variety,
concentration,
synthesis
conditions.
Consequently,
formed
display
notable
diversity
physical
chemical
subsequently
impacting
functionality.
manufactured
using
green
methods
extensive,
beneficial
effects
antibacterial
activity
against
various
pathogens,
anti-inflammatory
possible
anticancer
activities.
Nanoparticles
have
been
integrated
into
wound
dressings,
used
carriers
medication
delivery,
utilized
biosensing
imaging
applications.
enhanced
biocompatibility
reduced
toxicity
green-processed
techniques,
comparison
those
made
approaches,
make
very
appealing
use
contexts.
Moreover,
paper
examines
mechanisms,
explicitly
focusing
on
involvement
phytochemicals
processes
reduction
stabilization.
Additionally,
emphasizes
difficulties
potential
future
directions
optimizing
processes,
increasing
capacity,
facilitating
therapeutic
