Asian Journal of Organic Chemistry,
Journal Year:
2023,
Volume and Issue:
13(4)
Published: Dec. 15, 2023
Abstract
A
Pd‐catalyzed
oxidative
dual
C−H
carbonylation
has
been
developed
starting
from
commercially
available
diarylamines,
in
which
the
Cr(CO)
6
served
as
a
safe
carbonyl
source.
This
method
provides
facile
and
atom‐economic
approach
toward
diversified
acridone
derivatives
moderate
to
good
yields,
features
with
functional
group
compatibility,
operational
safety
easy
scale‐up.
Organic Chemistry Frontiers,
Journal Year:
2024,
Volume and Issue:
11(12), P. 3491 - 3496
Published: Jan. 1, 2024
The
use
of
a
ligand
to
tune
palladium-catalyzed
intramolecular
Heck
gem
-difluorovinylation
and
carboxylation
is
reported.
Sodium
difluorochloroacetate
(ClCF
2
COONa)
acts
as
both
difluorocarbene
(:CF
)
carboxyl
source.
European Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
unknown
Published: July 2, 2024
Abstract
A
Pd‐catalyzed
carbonylative
Heck
reaction
of
2‐iodophenyl
alkenyl
ether
using
Mo(CO)
6
as
a
safe
CO
source
has
been
developed.
This
research
provides
an
atom‐economic
and
straightforward
route
for
the
efficient
construction
benzofuran‐3(2
H
)‐one
scaffolds
with
C2
quaternary
center
in
moderate
to
good
yields,
which
features
operational
safety,
functional
group
compatibility
easy
scale‐up.
ChemistrySelect,
Journal Year:
2023,
Volume and Issue:
8(6)
Published: Feb. 8, 2023
Abstract
This
review
aims
to
collect
and
analyze
recent
results
with
respect
the
use
of
varied
palladium
preparations
in
synthesis
five‐membered
nitrogen
heterocycles
including
condensed
derivatives.
Results
have
been
selected
focus
on
studies
last
three
years.
Furthermore,
a
common
feature
all
methods
treated
here
is
that
nitrogen‐containing
ring
formed
via
closing
appropriate
starting
materials.
Selected
examples
discussed
will
reveal
plethora
products
from
small
monocycles
multi‐ring
systems
can
be
successfully
accessed.
Major
features
are
wide
product
ranges,
high
yields
stereoselectivities
often
achieved
under
mild
reaction
conditions.
Organic Letters,
Journal Year:
2023,
Volume and Issue:
25(32), P. 5951 - 5956
Published: Aug. 3, 2023
A
Pd-catalyzed
carbonylative
dearomatization
via
an
acyl
Pd
complex
has
been
developed.
Diversified
carbonyl-containing
spirocyclic
indolenines
with
all-carbon
quaternary
center
were
constructed
in
efficient
and
straightforward
way
good
to
excellent
yields.
The
protocol
features
a
simple
catalytic
system,
operational
simplicity,
broad
substrate
scope,
easy
scale-up,
versatile
transformations.
In
addition,
the
asymmetric
reaction
was
initially
explored
moderate
enantioselectivity.
Angewandte Chemie,
Journal Year:
2022,
Volume and Issue:
134(17)
Published: Feb. 17, 2022
Abstract
Controllable
production
of
α‐keto
amides
and
from
the
same
substrates
is
an
attractive
goal
in
field
transition‐metal‐catalyzed
(double‐)carbonylation.
Herein,
a
novel
copper‐catalyzed
highly
selective
double
carbonylation
alkyl
bromides
has
been
developed.
Moderate
to
good
yields
were
obtained
as
only
products.
In
case
iodides,
double‐
mono‐carbonylation
can
be
achieved
controllably
under
different
conditions.
European Journal of Organic Chemistry,
Journal Year:
2024,
Volume and Issue:
27(31)
Published: June 6, 2024
Abstract
An
efficient
method
for
the
conversion
of
biphenyl
acrylamides
to
dibenzoazepinones
with
−SCF
3
incorporation
is
described.
This
operationally
simple
radical
cascade
reaction
employs
CAN
as
an
oxidant
and
exhibits
good
functional
group
tolerance.
Substrates
featuring
−OCH
,
−CH
−Br
or
−Cl
at
para
‐position
aromatic
ring
a
preference
ipso
‐cyclization
due
intervention
DMSO
in
reaction.
Density
theory
(DFT)
calculations
provide
valuable
insights
into
reaction's
energetics
product
selectivity.
Asian Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
11(5)
Published: April 4, 2022
Abstract
Synthesis
of
N‐
aryl
α
‐ketoamides,
‐ketoesters
and
‐ketothioesters
were
demonstrated
from
Ts
Boc
‐ketoamides
via
transamidation
transesterification
reactions.
The
reactions
proceeded
at
room
temperature
in
the
presence
DBU
provided
desired
products
good
to
excellent
yields
a
short
time.
A
regioselective
synthesis
biologically
relevant
quinoxalinones
was
achieved
nitration
followed
by
reduction
The Journal of Organic Chemistry,
Journal Year:
2022,
Volume and Issue:
88(8), P. 5226 - 5230
Published: Dec. 29, 2022
A
palladium-catalyzed
domino
Heck
cyclization/carbonylative
Hiyama-Denmark
cross-coupling
reaction
between
alkene-tethered
aryl
iodides
and
silylcarboxylic
acids
is
presented.
This
proceeds
well
without
toxic
carbon
monoxide
(CO)
gas
has
good
functional
group
tolerance,
providing
an
alternative
access
to
carbonyl-containing
oxindoles.
In
this
transformation,
play
a
dual
role
as
CO
source
nucleophile.
