Recent Advances of Fe(III)/Fe(II)-MPNs in Biomedical Applications DOI Creative Commons
Weipeng Chen, Miao Liu,

Hanping Yang

et al.

Pharmaceutics, Journal Year: 2023, Volume and Issue: 15(5), P. 1323 - 1323

Published: April 23, 2023

Metal–phenolic networks (MPNs) are a new type of nanomaterial self-assembled by metal ions and polyphenols that have been developed rapidly in recent decades. They widely investigated, the biomedical field, for their environmental friendliness, high quality, good bio-adhesiveness, bio-compatibility, playing crucial role tumor treatment. As most common subclass MPNs family, Fe-based frequently used chemodynamic therapy (CDT) phototherapy (PTT), where they often as nanocoatings to encapsulate drugs, well Fenton reagents photosensitizers improve therapeutic efficiency substantially. In this review, strategies preparing various types first summarized. We highlight advantages under different species polyphenol ligands application treatments. Finally, some current problems challenges MPNs, along with future perspective on applications, discussed.

Language: Английский

Recent advances of cancer chemodynamic therapy based on Fenton/Fenton-like chemistry DOI Creative Commons

Changyu Cao,

Xiaorui Wang,

Nan Yang

et al.

Chemical Science, Journal Year: 2021, Volume and Issue: 13(4), P. 863 - 889

Published: Nov. 29, 2021

Applying Fenton chemistry in the tumor microenvironment (TME) for cancer therapy is most significant feature of chemodynamic (CDT). Owing to mild acid and overexpressed H2O2 TME, more cytotoxic hydroxyl radicals (˙OH) are generated cells via Fenton-like reactions. Without external stimulus drug resistance generation, reactive oxygen species (ROS)-mediated CDT exhibits a specific desirable anticancer effect has been seen as promising strategy therapy. However, optimizing treatment efficiency TME still challenging because limited catalytic agents strong antioxidant capacity TME. Hence, scientists trying their best design fabricate many with excellent activity remodeling optimal CDT. In this perspective, latest progress discussed, some representative examples presented. Consequently, strategies further guided by provided. Most importantly, several feasible ways developing future offered reference.

Language: Английский

Citations

198
Advances in tannic acid-incorporated biomaterials: Infection treatment, regenerative medicine, cancer therapy, and biosensing DOI
Ashkan Bigham, Vahid Rahimkhoei, Payam Abasian

et al.

Chemical Engineering Journal, Journal Year: 2021, Volume and Issue: 432, P. 134146 - 134146

Published: Dec. 29, 2021

Language: Английский

Citations

166
Pharmacological effects and mechanisms of tannic acid DOI Open Access
Jing Wang, Xiaolan Chen, Yu Chen

et al.

Biomedicine & Pharmacotherapy, Journal Year: 2022, Volume and Issue: 154, P. 113561 - 113561

Published: Aug. 24, 2022

In recent years, increasing attention has been paid to the pharmacological efficacy of tannins. Tannic acid (TA), simplest hydrolysable tannin that approved by FDA as a safe food additive, is one most important components these traditional medicines. Studies have shown TA displays wide range activities, such anti-inflammatory, neuroprotective, antitumor, cardioprotective, and anti-pathogenic effects. Here, we summarize known effects associated mechanisms TA. We focus on effect mechanism in various animal models inflammatory disease organ, brain, cardiovascular injury. Moreover, discuss possible molecular targets signaling pathways TA, addition TA-based nanoparticles combination with chemotherapeutic drugs.

Language: Английский

Citations

147
Polyphenol-based hydrogels: Pyramid evolution from crosslinked structures to biomedical applications and the reverse design DOI Creative Commons
Zimu Li, Zhidong Chen, Hongzhong Chen

et al.

Bioactive Materials, Journal Year: 2022, Volume and Issue: 17, P. 49 - 70

Published: Feb. 1, 2022

As a kind of nature-derived bioactive materials, polyphenol-based hydrogels possess many unique and outstanding properties such as adhesion, toughness, self-healing due to their specific crosslinking structures, which have been widely used in biomedical fields including wound healing, antitumor, treatment motor system injury, digestive disease, oculopathy, bioelectronics. In this review, starting with the classification common hydrogels, pyramid evolution process from structures derived then applications is elaborated, well efficient reverse design considerations hydrogel systems are proposed. Finally, existing problems development prospects these materials discussed. It hoped that perspective review can promote further innovation breakthroughs future.

Language: Английский

Citations

121
Recent progress in tannic acid-driven antibacterial/antifouling surface coating strategies DOI Open Access
Gnanasekar Sathishkumar,

Kasi Gopinath,

Kai Zhang

et al.

Journal of Materials Chemistry B, Journal Year: 2022, Volume and Issue: 10(14), P. 2296 - 2315

Published: Jan. 1, 2022

Tannic acid-based bioinspired coating strategies for tethering functional materials or molecules on different medical substrates resisting bacterial pathogens and fouling agents.

Language: Английский

Citations

100
Ultrastrong underwater adhesion on diverse substrates using non-canonical phenolic groups DOI Creative Commons
Bohan Cheng, Jinhong Yu, Toma Arisawa

et al.

Nature Communications, Journal Year: 2022, Volume and Issue: 13(1)

Published: April 13, 2022

Abstract Robust underwater adhesion is challenging because a hydration layer impedes the interaction between substrates and adhesives. Phenolic adhesives inspired by marine creatures such as mussels were extensively studied, but these have not reached strength substrate diversity of Man-made dry Here, we report class ultrastrong with molecular phenolic designs extending beyond what nature has produced. These non-canonical polymers show versatile on various materials, strengths exceeding 10 MPa metal. Incorporating even just small amount (<10%) groups into polymer sufficient for dramatically enhancing adhesion, suggesting that this new materials will be incorporated industrial systems in future.

Language: Английский

Citations

91
Tannic Acid–Iron Complex-Based Nanoparticles as a Novel Tool against Oxidative Stress DOI Creative Commons
Carlotta Pucci, Chiara Martinelli, Daniele De Pasquale

et al.

ACS Applied Materials & Interfaces, Journal Year: 2022, Volume and Issue: 14(14), P. 15927 - 15941

Published: March 30, 2022

Accumulation of reactive oxygen species in cells leads to oxidative stress, with consequent damage for cellular components and activation cell-death mechanisms. Oxidative stress is often associated age-related conditions, as well several neurodegenerative diseases. For this reason, antioxidant molecules have attracted a lot attention, especially those derived from natural sources─like polyphenols tannins. The main issue related the use antioxidants their inherent tendency be oxidized, quick enzymatic degradation biological fluids, poor bioavailability. Nanomedicine, sense, has helped finding new solutions deliver protect antioxidants; however, concentration encapsulated molecule conventional nanosystems could very low and, therefore, less effective. We propose exploit properties tannic acid, known plant-derived antioxidant, chelate iron ions, forming hydrophobic complexes that can coated biocompatible biodegradable phospholipid improve stability media. By combining nanoprecipitation hot sonication procedures, we obtained three-dimensional networks composed acid-iron hydrodynamic diameter ≈200 nm. These nanostructures show scavenging activity after induction an acute chemical pro-oxidant insult; moreover, they also demonstrated counteract induced by both vitro on vivo model organism (planarians).

Language: Английский

Citations

75
An injectable antibacterial chitosan-based cryogel with high absorbency and rapid shape recovery for noncompressible hemorrhage and wound healing DOI

Yingping Zhang,

Yue Wang, Lin Chen

et al.

Biomaterials, Journal Year: 2022, Volume and Issue: 285, P. 121546 - 121546

Published: April 29, 2022

Language: Английский

Citations

72
Bio-based tannic acid as a raw material for membrane surface modification DOI

Shiyu Zhou,

Yang Qu, Bowen Yang

et al.

Desalination, Journal Year: 2023, Volume and Issue: 555, P. 116535 - 116535

Published: March 11, 2023

Language: Английский

Citations

59
Research progress of polyphenols in nanoformulations for antibacterial application DOI Creative Commons
Chang Liu,

Shuhan Dong,

Xue Wang

et al.

Materials Today Bio, Journal Year: 2023, Volume and Issue: 21, P. 100729 - 100729

Published: July 11, 2023

Infectious disease is one of the top 10 causes death worldwide, especially in low-income countries. The extensive use antibiotics has led to an increase antibiotic resistance, which poses a critical threat human health globally. Natural products such as polyphenolic compounds and their derivatives have been shown positive therapeutic effects antibacterial therapy. However, inherent physicochemical properties limit pharmaceutical effects, short half-lives, chemical instability, low bioavailability, poor water solubility. Nanoformulations promising advantages improving activity by controlling release drugs enhancing bioavailability polyphenols. In this review, we listed classification mechanisms compounds. More importantly, nanoformulations for delivery polyphenols agent were summarized, including different types nanoparticles (NPs) polymer-based NPs, metal-based lipid-based nanoscaffolds nanogels, nanofibers, nanoemulsions. At same time, also presented potential biological applications nano-system enhance ability polyphenols, aiming provide new perspective antibiotic-free treatment infectious diseases.

Language: Английский

Citations

49