Wound healing assay on a gravity-driven unidirectional perfusion microfluidic device DOI
Yi‐Rong Chen, Yuanyuan Xie, Wen Sun

et al.

Microchemical Journal, Journal Year: 2024, Volume and Issue: unknown, P. 112289 - 112289

Published: Nov. 1, 2024

Language: Английский

Developing natural polymers for skin wound healing DOI Creative Commons
Han Zhang,

Xiang Lin,

Xinyue Cao

et al.

Bioactive Materials, Journal Year: 2023, Volume and Issue: 33, P. 355 - 376

Published: Nov. 26, 2023

Natural polymers are complex organic molecules that occur in the natural environment and have not been subjected to artificial synthesis. They frequently encountered various creatures, including mammals, plants, microbes. The aforementioned commonly derived from renewable sources, possess a notable level of compatibility with living organisms, limited adverse effect on environment. As result, they hold considerable significance development sustainable environmentally friendly goods. In recent times, there has advancement investigation potential uses field biomedicine, specifically relation biomaterials exhibit antibacterial antioxidant characteristics. This review provides comprehensive overview prevalent utilized biomedical domain throughout preceding two decades. this paper, we present examination components typical methods for preparation based polymers. Furthermore, summarize application polymer materials each stage skin wound repair. Finally, key findings insights into limitations current elucidate prospects their future field.

Language: Английский

Citations

109

Recent developments and future perspectives of microfluidics and smart technologies in wearable devices DOI Open Access

Sasikala Apoorva,

Nam‐Trung Nguyen, Kamalalayam Rajan Sreejith

et al.

Lab on a Chip, Journal Year: 2024, Volume and Issue: 24(7), P. 1833 - 1866

Published: Jan. 1, 2024

Wearable devices are increasingly popular in health monitoring, diagnosis, and drug delivery. Advances allow real-time analysis of biofluids like sweat, tears, saliva, wound fluid, urine.

Language: Английский

Citations

27

Triboelectric Nanogenerators-Based Therapeutic Electrical Stimulation on Skin: from Fundamentals to Advanced Applications DOI
Weijiang Wang, Wentao Sun, Yanfeng Du

et al.

ACS Nano, Journal Year: 2023, Volume and Issue: 17(11), P. 9793 - 9825

Published: May 30, 2023

Discovery of the amazing and vital therapeutic roles electrical stimulation (ES) on skin has sparked tremendous efforts to investigate ES suppliers. Among them, triboelectric nanogenerators (TENGs), as a self-sustainable bioelectronic system, can generate self-powered biocompatible for achieving superior effects applications. Here, brief review application TENGs-based is presented, with specific discussions fundamentals its feasibility be applied adjusting physiological pathological processes skin. Then, comprehensive in-depth depiction emerging representative applications categorized reviewed, particular descriptions about antibacterial therapy, promoting wound healing, facilitating transdermal drug delivery. Finally, challenges perspectives further advancing toward more powerful versatile strategy are discussed, particularly regarding opportunities in fundamental multidisciplinary research biomedical

Language: Английский

Citations

35

Robust and Wet Adhesive Self-Gelling Powders for Rapid Hemostasis and Efficient Wound Healing DOI

Zhao Wenbin,

Wentao Sun, Weijiang Wang

et al.

ACS Applied Materials & Interfaces, Journal Year: 2024, Volume and Issue: 16(6), P. 6756 - 6771

Published: Jan. 31, 2024

Healing traumatic wounds is arduous, leaving miscellaneous demands for ideal wound dressings, such as rapid hemostasis, superior wet tissue adhesion, strong mechanical properties, and excellent antibacterial activity. Herein, we report a self-gelling, adhesive, stretchable (polyethylenimine/poly(dimethylammonium chloride)/(poly(acrylic acid)/poly(sodium styrenesulfonate)/alkylated chitosan)) ((PEI/PDDA)/(PAA/PSS)/ACS) powder new option. The self-gel utilizes noncovalent interactions among in situ formed PDDA/PSS nanoparticles PEI/PAA polymetric matrices to earn sensational properties tensile strength while incorporating ACS obtain fast hemostasis therapeutic capacities. can form hydrogel patch within 3 s upon liquid absorption, capable of resisting pressure higher than twice the blood pressure. Deposition self-gelling powders on various wounds, rat liver femoral artery stop bleeding 10 lessen amount 6-fold plus corresponding models. Furthermore, significantly advance chronic healing process by displaying high rate low inflammatory response promoting formation vessels regeneration. satisfactory sufficient ease usage, adaptability complex capacities (PEI/PDDA)/(PAA/PSS)/ACS render them profound dressing biomaterial.

Language: Английский

Citations

15

Micro-nano-fabrication of green functional materials by multiphase microfluidics for environmental and energy applications DOI Creative Commons
Qi Cheng, Tao Zhou, Xingjiang Wu

et al.

Green Energy & Environment, Journal Year: 2023, Volume and Issue: 9(8), P. 1199 - 1219

Published: June 8, 2023

Multiphase microfluidic has emerged as a powerful platform to produce novel materials with tailor-designed functionalities, fabrication provides precise controls over the size, component, and structure of resultant materials. Recently, functional well-defined micro-/nanostructures fabricated by microfluidics find important applications environmental energy This review first illustrated in detail how different structures or shapes droplet jet templates are formed typical configurations channel networks multiphase flow systems. Subsequently, recent progresses on several representative applications, such water purification, collecting storage, were overviewed. Finally, it is envisioned that integrating other will play increasing role contributing remediation storage near future.

Language: Английский

Citations

21

Recent advances in the microfluidic generation of shape-controllable hydrogel microparticles and their applications DOI Creative Commons
Yingzhe Liu, Zhuo Chen, Jianhong Xu

et al.

Green Chemical Engineering, Journal Year: 2023, Volume and Issue: 5(1), P. 16 - 30

Published: Feb. 28, 2023

Hydrogel microparticles, generally accepted as significant green materials, have been widely used in chemical, biological, and biomedical fields owing to their excellent biocompatibility, biodegradability, non-cytotoxicity. Among these, non-spherical hydrogel microparticles with diverse shape anisotropy great potential applications such drug delivery, cellular interaction, micromotors, etc. Benefiting from shapes, functionalities cannot be satisfied by the typical spherical types. Recently, microfluidics precise control domination of fluids at microflow sizes has emerged a powerful method for synthesizing shape-controllable good monodispersity unique morphology. In this review, we tried provide an overview production composed emphasizing microfluidic approaches. Furthermore, brief introduction current is also presented.

Language: Английский

Citations

19

Oxygen-releasing biomaterials for regenerative medicine DOI
Zhaojun Wang, T. Chen, Xin Li

et al.

Journal of Materials Chemistry B, Journal Year: 2023, Volume and Issue: 11(31), P. 7300 - 7320

Published: Jan. 1, 2023

This review provides a comprehensive overview of oxygen-releasing biomaterials for regenerative medicine.

Language: Английский

Citations

19

Advanced function, design and application of skin substitutes for skin regeneration DOI Creative Commons
Miao Zhang, Jiyao Xing, Yingjie Zhong

et al.

Materials Today Bio, Journal Year: 2023, Volume and Issue: 24, P. 100918 - 100918

Published: Dec. 20, 2023

The development of skin substitutes aims to replace, mimic, or improve the functions human skin, regenerate damaged tissue, and replace enhance function. This includes artificial scaffolds devices designed for treatment, imitation, improvement function in wounds injuries. Therefore, tremendous efforts have been made develop functional substitutes. However, there is still few reports systematically discuss relationship between advanced design requirements. In this paper, we review classification, functions, requirements Different manufacturing strategies such as hydrogels, 3D/4D printing, electrospinning, microfluidics are summarized. also introduces currently available clinical trials on market related regulatory Finally, prospects challenges field tissue engineering discussed.

Language: Английский

Citations

15

Microfluidic strategies for engineering oxygen-releasing biomaterials DOI
Zhiqiang Zhu, T. Chen, Yongqi Wu

et al.

Acta Biomaterialia, Journal Year: 2024, Volume and Issue: 179, P. 61 - 82

Published: April 1, 2024

Language: Английский

Citations

4

Progress and perspective of transition metal layered double hydroxides with oxygen vacancies for enhancing water splitting applications: A review DOI
Kai Chen, Dung Van Dao,

Sunny Yadav

et al.

Journal of environmental chemical engineering, Journal Year: 2024, Volume and Issue: 12(5), P. 113773 - 113773

Published: Aug. 6, 2024

Language: Английский

Citations

4