Alkaloids from Mackinlaya species and synthetic mackinazolinone derivatives: An overview DOI Creative Commons

Julie Jaouen,

Christian Bailly

Bioorganic & Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 117, P. 118018 - 118018

Published: Nov. 23, 2024

Language: Английский

Metal-free synthesis of carbamoylated dihydroquinolinones via cascade radical annulation of cinnamamides with oxamic acids DOI

Pallav Suman,

Kirti Tomar,

Chandra Shekhar Nishad

et al.

Organic & Biomolecular Chemistry, Journal Year: 2024, Volume and Issue: 22(9), P. 1821 - 1833

Published: Jan. 1, 2024

Metal-free synthesis of medicinally important carbamoylated dihydroquinolinones using readily available, cheap and environment-friendly materials with good to excellent yields.

Language: Английский

Citations

6
An Iron‐Catalyzed Three‐Component Radical Cascade Cyclization to Access Cyanoalkylsulfonyl Quinolino‐Quinazolinones DOI

Abuthayir Mohamathu Ghouse,

Uppalam Tarun,

Bathula Maheswari

et al.

Advanced Synthesis & Catalysis, Journal Year: 2024, Volume and Issue: 366(11), P. 2456 - 2460

Published: March 21, 2024

Abstract An iron(II)‐catalyzed cascade reaction, involving cyanoalkylsulfonylation and cyclization, has been devised to enable the synthesis of functionalized sulfonylated quinolino‐quinazolinone alkyl nitriles. This three‐component radical transformation exhibits excellent chemo‐ regioselectivity while functioning without need for external oxidizing or reducing agents. The cost‐effectiveness this catalytic system, together with its broad substrate application, which includes drug molecule derivatives, make approach efficient adaptable.

Language: Английский

Citations

4
Anthraquinone Sulfonates as Water‐Soluble Photocatalysts: Synthetic Applications and Perspectives DOI Creative Commons
D.M. Kolb, Andrey Fedulin, Burkhard Koenig

et al.

ChemPhotoChem, Journal Year: 2025, Volume and Issue: unknown

Published: May 4, 2025

Anthraquinone sulfonates are water‐soluble and cost‐effective photocatalysts that have been attracting increasing interest due to their unique features. Their sulfonate groups unlock the application of photoactive anthraquinone core in aqueous solution. Moreover, these readily available catalysts can engage with substrates through different activation modes, such as hydrogen atom transfer proton‐coupled electron events. However, date, reactivity has not fully explored further applications expected emerge. Herein, existing synthetic outlined future perspectives discussed.

Language: Английский

Citations

0
Visible-Light-Promoted Iron(II)/Lewis Base Catalysis for the Alkylation of Morita–Baylis–Hillman Acetates Using Carboxylic Acids DOI

Durga Golagani,

Kota Krishna Prakash,

Satyam Thapa

et al.

Organic Letters, Journal Year: 2024, Volume and Issue: unknown

Published: Oct. 1, 2024

A novel photoinduced Fe(OTf)

Language: Английский

Citations

3
Persulfate-Promoted Carbamoylation/Cyclization of Alkenes: Synthesis of Amide-Containing Quinazolinones DOI Creative Commons
Jia-Jun Tang, Mengyang Zhao,

Ying-Jun Lin

et al.

Molecules, Journal Year: 2024, Volume and Issue: 29(5), P. 997 - 997

Published: Feb. 25, 2024

The incorporation of amide groups into biologically active molecules has been proven to be an efficient strategy for drug design and discovery. In this study, we present a simple practical method the synthesis amide-containing quinazolin-4(3H)-ones under transition-metal-free conditions. This is achieved through carbamoyl-radical-triggered cascade cyclization N3-alkenyl-tethered quinazolinones. Notably, carbamoyl radical generated in situ from oxidative decarboxylative process oxamic acids presence (NH4)2S2O8.

Language: Английский

Citations

2
Visible-light-induced cascade radical cyclization for the synthesis of amide-functionalized fused quinazolinones DOI
Shenyuan Gao, Gang Xu, Jianhai Yang

et al.

Tetrahedron, Journal Year: 2024, Volume and Issue: 159, P. 134027 - 134027

Published: May 8, 2024

Language: Английский

Citations

2
Acid-catalyzed radical tandem alkylation/cyclization of unactivated alkenes with ketones: Access to ketoalkyl-substituted quinazolinone derivatives DOI

Jian-Li Wu,

Meng Yan,

Lulu Fan

et al.

Tetrahedron, Journal Year: 2024, Volume and Issue: 162, P. 134085 - 134085

Published: June 11, 2024

Language: Английский

Citations

2
Photocatalytic alkenes to ring-fused quinazolin-4(3H)-ones via proton-transfer shuttle using TFA DOI
Xianming Wang,

Xinhan Li,

Luqian Zou

et al.

Tetrahedron, Journal Year: 2024, Volume and Issue: 158, P. 133990 - 133990

Published: April 11, 2024

Language: Английский

Citations

1
Alkaloids from Mackinlaya species and synthetic mackinazolinone derivatives: An overview DOI Creative Commons

Julie Jaouen,

Christian Bailly

Bioorganic & Medicinal Chemistry, Journal Year: 2024, Volume and Issue: 117, P. 118018 - 118018

Published: Nov. 23, 2024

Language: Английский

Citations

0