Overview of Wells-Dawson Polyoxometalates: from structure and functionalization to application

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 519, P. 216091 - 216091

Published: July 30, 2024

Wells-Dawson polyoxometalates (WD POMs) are an important subgroup within the diverse family of POMs. In last two decades, there has been remarkable progress in structure modification and post-functionalization WD POMs, which unlocked their enormous potential across various domains, including energy materials, catalysis (photocatalysis, electrocatalysis), functional materials (sensors, optical electrochromic magnetic materials) or biology/medicine (anticancer antibacterial activities). What makes these systems particularly captivating is highly adaptable topological structure, combined with versatile functionalization methods consequently precise design control, transfers into a wide range applications. our comprehensive review, we focus on exploration intricate structural characteristics play pivotal role properties. Moreover, exciting promising applications POMs areas science disciplines highlighted. Our aim to shed light current state art, identify emerging trends, provide insights future directions POM research, still being expanded, especially given rapid development continuous novel subunit functionalities. By doing so, hope contribute better understanding inspire further innovation utilization.

Language: Английский

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Polyoxometalate-based materials in therapeutic and biomedical applications: current status and perspective

Dalton Transactions, Journal Year: 2025, Volume and Issue: unknown

Published: Jan. 1, 2025

Recent advances in polyoxometalate (POM)-based materials with biomedical applications indicate significant potential the therapeutic field. The scientific community aims to advance these enhance bioorthogonal chemistry of POMs.

Language: Английский

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GSH/pH dual-activated POM@MOF for tumor cell-specific synergistic photothermal and chemodynamic therapy

Inorganic Chemistry Frontiers, Journal Year: 2024, Volume and Issue: 11(14), P. 4439 - 4448

Published: Jan. 1, 2024

A tumor microenvironment-specifically activated POM@MOF was developed for PTT/CDT combination therapy against cells.

Language: Английский

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Catalytic efficiency and kinetic analysis of manganese Polyoxometalate Heterogenized in MIL-100-Fe for selective Olefin oxidation using H2O2

Molecular Catalysis, Journal Year: 2024, Volume and Issue: 567, P. 114456 - 114456

Published: Aug. 20, 2024

Language: Английский

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Versatile POMOF-based materials: Synthesis, mechanism, topology and catalytic applications

Coordination Chemistry Reviews, Journal Year: 2024, Volume and Issue: 524, P. 216304 - 216304

Published: Nov. 8, 2024

Language: Английский

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Bio-Based Industries and Their Products in the Global South

Published: Jan. 1, 2025

Language: Английский

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Cascade-enhanced based-polyoxometalates nanozyme for glutathione detection and tumor cell disruption

Talanta, Journal Year: 2025, Volume and Issue: 291, P. 127890 - 127890

Published: March 3, 2025

Language: Английский

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Polyoxometalates: Versatile nanomedicine candidates for precise cancer therapy

Chemical Engineering Journal, Journal Year: 2025, Volume and Issue: unknown, P. 162335 - 162335

Published: April 1, 2025

Language: Английский

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An injectable dual-layer chitosan-alginate nano-hydrogel incorporated Cu(I)-isopolymolybdate-based metal-organic framework tailored for three-in-one anti-cancer nanotherapy

International Journal of Biological Macromolecules, Journal Year: 2024, Volume and Issue: 282, P. 137381 - 137381

Published: Nov. 7, 2024

Language: Английский

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Monolacunary Wells-Dawson Polyoxometalate as a Novel Contrast Agent for Computed Tomography: A Comprehensive Study on In Vivo Toxicity and Biodistribution

International Journal of Molecular Sciences, Journal Year: 2024, Volume and Issue: 25(5), P. 2569 - 2569

Published: Feb. 22, 2024

Polyoxotungstate nanoclusters have recently emerged as promising contrast agents for computed tomography (CT). In order to evaluate their clinical potential, in this study, we evaluated the vitro CT imaging properties, potential toxic effects vivo, and tissue distribution of monolacunary Wells–Dawson polyoxometalate, α2-K10P2W17O61.20H2O (mono-WD POM). Mono-WD POM showed superior X-ray attenuation compared other tungsten-containing (its parent WD-POM Keggin POM) standard iodine-based agent (iohexol). The calculated linear slope mono-WD was significantly higher WD-POM, POM, iohexol (5.97 ± 0.14 vs. 4.84 0.05, 4.55 0.16, 4.30 0.09, respectively). Acute oral (maximum-administered dose (MAD) = 960 mg/kg) intravenous administration (1/10, 1/5, 1/3 MAD) did not induce unexpected changes rats’ general habits or mortality. Results blood gas analysis, CO-oximetry status, levels electrolytes, glucose, lactate, creatinine, BUN demonstrated a dose-dependent tendency 14 days after POM. most significant differences control were observed MAD, being approximately seventy times than typically used (0.015 mmol W/kg) tungsten-based agents. highest tungsten deposition found kidney (1/3 MAD—0.67 0.12; 1/5 MAD—0.59 0.07; 1/10 MAD—0.54 0.05), which corresponded detected morphological irregularities, electrolyte imbalance, increased levels.

Language: Английский

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